ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Incidence of Autoresuscitation in Donation after Cardiac Death Donors

    C. W. Koo1, R. A. Helmick1, K. Van Frank2, K. Gilley2, J. D. Eason1

    1UTHSC / Methodist University Hospital Transplant Institute, Memphis, TN, 2Mid South Transplant Foundation, Memphis, TN

    *Purpose: Donation after cardiac death (DCD) donors are subject to an observation period after asystole to monitor for cardiopulmonary autoresuscitation (AR). Periods vary between and…
  • 2019 American Transplant Congress

    Tacrolimus Pharmacokinetics in Young, Middle Age and Older Renal Transplant Recipients- Impact of CYP3A5*3*6*7 Metabolic Composite

    K. Tornatore1, K. Attwood2, D. Brazeau3, R. Venuto4

    1University at Buffalo; School of Pharmacy, Buffalo, NY, 2Biostatistics, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 3Marshall University; School of Medicine, Huntington, WV, 4University at Buffalo; School of Medicine, Buffalo, NY

    *Purpose: In spite of increased renal transplantation in patients over 60 years and the need for age-adjusted tacrolimus maintenance immunosuppression, limited pharmacokinetic comparisons between young,…
  • 2019 American Transplant Congress

    Impact of Functional Delayed Graft Function in the Modern Era of Kidney Transplantation

    D. Cucchiari, A. Molina-Andujar, E. Montagud-Marrahi, J. Rovira, F. Diekmann

    Renal Transplant Unit, Hospital Clínic, Barcelona, Spain

    *Purpose: the classical definition of Delayed Graft Function (DGF) (i.e. need of dialysis during the first week after kidney transplant) depends on the physician attitude…
  • 2019 American Transplant Congress

    Predicted Indirectly Recognizable H L A Epitopes Are Associated with T-cell Mediated Rejection among Kidney Transplant Recipients with Preformed and De Novo Donor-Reactive T-cells

    T. Schachtner1, M. Stein2, N. M. Otto3, P. M. Reinke2

    1Nephrology, University Hospital Zurich, Zurich, Switzerland, 2Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany, 3Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berin, Germany

    *Purpose: Very recently Predicted Indirectly ReCognizable HLA Epitopes (PIRCHE) have been suggested to demonstrate early and late effects on kidney allograft outcomes. The association between…
  • 2019 American Transplant Congress

    Access To The Kidney Transplant Waitlist For Patients With Hiv And End-stage Renal Disease

    A. A. Shaffer1, H. Ying2, N. Chu1, A. G. Thomas3, C. Haugen2, S. Norman4, D. L. Segev1, M. A. McAdams-DeMarco1

    1Surgery & Epidemiology, Johns Hopkins University, Baltimore, MD, 2Surgery, Johns Hopkins University, Baltimore, MD, 3Epidemiology, University of North Carolina, Chapel Hill, NC, 4Surgery, University of Michigan, Ann Arbor, MI

    *Purpose: Patients with HIV and end-stage renal disease (ESRD) experience higher mortality on dialysis than those without HIV. These HIV+ dialysis patients may face barriers…
  • 2019 American Transplant Congress

    Quantifying Differential Infection Risks in HLA- and/or ABO- Incompatible Kidney Transplant Recipients

    R. Avery1, R. Montgomery2, J. Motter1, A. Massie1, E. Kraus1, K. Marr1, B. Lonze2, N. Alachkar1, K. Jackson1, M. Holechek1, D. Ostrander1, N. Desai1, M. Waldram1, S. Shoham1, S. Mehta1, J. Hiller1, J. Langlee1, S. Young1, D. Segev1, J. Garonzik Wang1

    1Johns Hopkins, Baltimore, MD, 2New York University, New York, NY

    *Purpose: Desensitization has enabled kidney transplantation across HLA-and/or ABO barriers and has conferred survival benefit to patients who lack compatible living donors (CLDKT). However, due…
  • 2019 American Transplant Congress

    Incorporating Tangible Benefits into the Risk-Benefit Analysis of Living Organ Donation Decisions

    M. Robin1, S. Rasmussen2, A. Saha2, A. Eno2, M. Waldram2, D. Segev2, M. Henderson2

    1University of Maryland, Baltimore, MD, 2Johns Hopkins University, Baltimore, MD

    *Purpose: The risk-benefit framework currently used in living organ donation presumes all benefit is afforded to the recipient, whereas the donor only assumes risks. However,…
  • 2019 American Transplant Congress

    Tissue Resident Memory T Cells in Murine Renal Transplantation

    K. Abou-Daya, D. Zhao, R. Tieu, A. Williams, M. Oberbarnscheidt, F. Lakkis

    Starzl Transplantation Institute, Pittsburgh, PA

    *Purpose: The newly identified tissue resident subset of memory T cells (TRM) provides immune surveillance in the tissue and first response against infections. They are…
  • 2019 American Transplant Congress

    Multicenter Cohort Study of Frailty and Access to Kidney Transplantation

    C. Haugen1, N. Chu1, H. Ying1, N. Desai1, S. Norman2, J. Garonzik-Wang1, A. Bingaman3, D. Segev1, M. McAdams-DeMarco1

    1JHU, Baltimore, MD, 2MIchigan, Ann Arbor, MI, 3Methodist, San Antonio, TX

    *Purpose: Frailty, a syndrome distinct from comorbidity and disability, is clinically manifested as a decreased resistance to stressors and is present in up to 35%…
  • 2019 American Transplant Congress

    Ten Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients

    J. Leventhal1, J. Galvin1, L. Gallon1, D. Stare1, K. Ravindra2, M. Horwitz2, M. Abecassis1, S. Ildstad3

    1Northwestern U, Chicago, IL, 2Duke U, Durham, NC, 3U Louisville, Louisville, KY

    *Purpose: 37 subjects have been transplanted in a phase 2 protocol to induce tolerance in recipients of living donor renal allografts (KTx) based upon tolerogenic…
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