ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Tissue Resident Memory T Cells in Murine Renal Transplantation

    K. Abou-Daya, D. Zhao, R. Tieu, A. Williams, M. Oberbarnscheidt, F. Lakkis

    Starzl Transplantation Institute, Pittsburgh, PA

    *Purpose: The newly identified tissue resident subset of memory T cells (TRM) provides immune surveillance in the tissue and first response against infections. They are…
  • 2019 American Transplant Congress

    Multicenter Cohort Study of Frailty and Access to Kidney Transplantation

    C. Haugen1, N. Chu1, H. Ying1, N. Desai1, S. Norman2, J. Garonzik-Wang1, A. Bingaman3, D. Segev1, M. McAdams-DeMarco1

    1JHU, Baltimore, MD, 2MIchigan, Ann Arbor, MI, 3Methodist, San Antonio, TX

    *Purpose: Frailty, a syndrome distinct from comorbidity and disability, is clinically manifested as a decreased resistance to stressors and is present in up to 35%…
  • 2019 American Transplant Congress

    Ten Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients

    J. Leventhal1, J. Galvin1, L. Gallon1, D. Stare1, K. Ravindra2, M. Horwitz2, M. Abecassis1, S. Ildstad3

    1Northwestern U, Chicago, IL, 2Duke U, Durham, NC, 3U Louisville, Louisville, KY

    *Purpose: 37 subjects have been transplanted in a phase 2 protocol to induce tolerance in recipients of living donor renal allografts (KTx) based upon tolerogenic…
  • 2019 American Transplant Congress

    Aorto-Iliac Calcification is a Risk Factor for Inferior Patient and Graft Survival in Kidney Transplant Recipients; A Systematic Review and Meta-Analysis

    A. A. Rijkse, J. L. van Dam, H. J. Kimenai, J. N. IJzermans, R. C. Minnee

    HPB/Transplant surgery, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: While the incidence of transplanting a kidney onto atherosclerotic iliac arteries is becoming more common, little is known about the clinical outcome. We performed…
  • 2019 American Transplant Congress

    The Use of Native Kidney Biopsy to Predict Renal Dysfunction Following Liver Transplantation

    D. O. Walls1, L. Muraveika1, M. B. Palmer2, D. L. Sawinski3, B. J. Keating1, P. L. Abt1

    1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Pathology, Hospital of the University of Pennsylvania, Philadelphia, PA, 3Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Acute and chronic kidney injury are a common occurrence for patients with end-stage liver disease and are associated with significant morbidity and mortality. We…
  • 2019 American Transplant Congress

    Single Nucleotide Polymorphisms in NFACT1 rs2290154 Associated with the Risk of T Cell-Mediated Rejection of Recipients Following Kidney Transplantation

    Z. Wang, S. Fei, H. Chen, L. Sun, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu

    No.300 Guangzhou Road of Nanjing, Nanjing, China

    *Purpose: Our study was to investigate the potential associations between the single nucleotide polymorphisms (SNPs) in NFATC1 and the risk of T cell-mediated rejection (TCMR)…
  • 2019 American Transplant Congress

    Hepatitis C Treatment and Transplant Outcomes in Liver Transplant Recipients with Hepatitis C Positive Donors

    I. Booth, J. Clark, J. C. LaMattina, A. Haririan, R. N. Barth, B. Ravichandran

    University of Maryland Medical Center, Baltimore, MD

    *Purpose: With direct-acting antivirals for hepatitis C virus (HCV), transplant centers have expanded the donor pool with positive short term outcomes with early HCV treatment.…
  • 2019 American Transplant Congress

    Ex Vivo Normothermic Perfusion Of Discarded Human Kidneys Reveals Cold-storage-induced Renal Fibrinogen And Provides A Platform For Therapeutic Repair

    J. DiRito1, S. A. Hosgood2, M. Reschke3, M. L. Nicholson2, G. T. Tietjen4

    1Surgery, Yale University & University of Cambridge, New Haven, CT, 2Surgery, University of Cambridge, Cambridge, United Kingdom, 3Biomedical Engineering, Yale University, New Haven, CT, 4Surgery - Transplantation, Yale University, New Haven, CT

    *Purpose: The purpose of this study was to: 1) determine the cause of microvascular obstructions that arise during ex vivo normothermic perfusion (NMP) of human…
  • 2019 American Transplant Congress

    Racial Disparity in Pre-Kidney Transplant Work-Up

    J. Buggs1, H. Mohamed2, C. Myer3, S. Lloyd4, E. Rogers1, H. Pearson1, J. Clement1, D. Zunick1, A. Kumar2, V. Bowers1

    1Tampa General Hospital, Tampa, FL, 2University of South Florida, Tampa, FL, 3University of Tampa, Tampa, FL, 4University of Florida, Gainesville, FL

    *Purpose: The purpose of this study was to evaluate the disparity, by race, for pre-kidney transplant work-up completion rates of referred patients.*Methods: We conducted a…
  • 2019 American Transplant Congress

    RNA Sequencing Guided Identification of Shared mRNAs in Human Kidney Allograft Recipients with Acute T Cell Mediated Rejection or Active Antibody Mediated Rejection

    B. Dooley1, A. Verma2, R. Ding1, C. Li1, C. Snopkowski1, H. Yang1, B. Botticelli1, S. Albakry1, E. Edusei1, T. Muthukumar1, M. Lubetzky1, D. Dadhania1, J. Lee1, O. Elemento2, M. Suthanthiran1

    1Transplantation Medicine, Weill Cornell Medical College, New York, NY, 2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY

    *Purpose: T cell help is essential for B cell production of antibodies to donor organ HLA. Because T cell-B cell interactions contribute to anti-allograft immunity,…
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