Am J Transplant, Volume 19, Suppl 3 Archives - Page 132 of 214 - ATC Abstracts

2019 American Transplant Congress
Early T Cell Infiltration is Modulated by PD-1/PD-L1 Interactions in Kidney Graft
Y. Shim, R. Fan, N. Dvorina, W. Baldwin
Inflammation and Immunity, Lerner Research Institute, Cleveland, OH
*Purpose: Allogeneic transplants elicit dynamic T cell responses that are modulated by positive and negative co-stimulatory receptors. We have investigated the impact of PD-1, a…
2019 American Transplant Congress
Excellent Outcomes in Liver Transplantation under Charity Care: An Opportunity to Mitigate Socio-Economic Disparities in Access to Transplantation
F. Paterno¹, J. Rosado¹, R. Olivo², S. Gavzy¹, L. Brown¹, D. Wilson¹, B. Koneru¹, N. Pyrsopoulos², J. V. Guarrera¹
¹Department of Surgery, Division of Transplant and Hepatobiliary Surgery, Rutgers New Jersey Medical School, Newark, NJ, ²Department of Medicine, Division of Hepatology, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Lack of health insurance is a major barrier in the access to health care even in the case of life-threatening conditions like end-stage liver…
2019 American Transplant Congress
The Centennial Allograft? Observation Of Greater Than 100-year Allograft Survival Is More Common Among Liver Allograft Recipients Than Renal Allograft Recipients.
J. F. Renz, A. C. Gruessner, R. C. Misawa, A. Masi, R. W. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: We investigated the occurrence of deceased-donor liver (DDOLT), deceased-donor renal (DDRT), and living-donor renal allografts (LDRT) that have achieved 100 years or more of…
2019 American Transplant Congress
CURATE.AI: Personalized Liver Transplant Tacrolimus Dosing
A. Zarrinpar¹, T. Kee², P. Wang³, J. Khong³, U. Kim¹, J. Chong², J. B. Jeong³, A. T. Truong², S. Tan², B. K. Betzler², W. Ng², C. Ho³, D. Ho²
¹Surgery, University of Florida, Gainesville, FL, ²National University of Singapore, Singapore, Singapore, ³UCLA, Los Angeles, CA
*Purpose: Transplant immunosuppressive regimens include multiple drugs with varying pharmacokinetics, metabolic pathways, and drug-drug interactions. This study aimed to use CURATE.AI, an artificial intelligence platform,…
2019 American Transplant Congress
Lower Alcohol Taxes Are Associated with Increased Liver Transplant Listing
N. T. Shen¹, M. Raver¹, N. Hutchison¹, A. Jesudian¹, J. Bray², B. Schackman³, R. S. Brown¹
¹Medicine; Division of Gastroenterology and Hepatology, New York Presbyterian Hospital - Weill Cornell, New York, NY, ²Economics, University of North Carolina at Greensboro, Greensboro, NC, Greensboro, NC, ³Healthcare Policy and Research, Weill Cornell Medicine, New York, NY
*Purpose: Alcoholic liver disease (ALD) is a leading indication for liver transplantation worldwide with rising prevalence. Whether relationships exist between transplant listing for ALD and…
2019 American Transplant Congress
Redox State of HMGB1 Drives Ischemia-Reperfusion Injury in Human Liver Transplantation
R. A. Sosa¹, A. Q. Terry¹, J. Nevarez-Mejia¹, M. Rossetti¹, B. V. Naini¹, V. M. Groysberg¹, F. M. Kaldas², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski², E. F. Reed¹
¹Pathology & Laboratory Medicine, UCLA, Los Angeles, CA, ²Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor of acute and chronic graft rejection in orthotopic liver transplantation (OLT) involving a complex interplay between…
2019 American Transplant Congress
Obese Simultaneous Pancreas And Kidney Transplant Recipients In Type 2 Diabetes Have Similar Risks Of Pancreas Failure As Non-obese
T. Alhamad¹, K. Espinoza¹, J. R. Wellen¹, S. Chang¹, D. C. Brennan², K. L. Lentine³
¹Washinton University in St. Louis, St. Louis, MO, ²Johns Hopkins University, Baltimore, MD, ³Saint Louis University, St. Louis, MO
*Purpose: In October 2014, United Network for Organ Sharing (UNOS) implemented criteria for simultaneous pancreas and kidney transplant (SPKT) in patients with c-peptide 2 >…
2019 American Transplant Congress
Pancreas Allograft Importation Should Be Fostered by Any Transplant Center Challenged by Excessively Long Waitlist Times
J. Torabi, J. P. Rocca, L. Lirano, Y. Azzizi, M. Ajaimy, C. Pynadath, E. Akalin, M. Kinkhabwala, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: Pancreas transplantation is a durable option for patients with insulin dependent diabetes. However, geographic inequity has created a supply side problem for our region.…
2019 American Transplant Congress
Pre-Operative C-Peptide Predicts Weight Gain after Pancreas Transplantation
J. Torabi, J. P. Rocca, E. Kestenbaum, M. Ajaimy, M. Kinkhabwala, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: Transplant recipients are susceptible to metabolic syndrome as typified by hyperglycemia, central obesity and increased insulin resistance after transplant, which may precede the onset…
2019 American Transplant Congress
Prevalence of Non-Adherence to Immunosuppressive Medications in Kidney Transplant Recipients, Barriers and Predictors
S. Taj¹, H. Baghaffar², D. Alnajjar², N. Almashabi³, S. Ismail⁴
¹King Saud Bin Abdulaziz University For Health Sciences, Jeddah, Saudi Arabia, ²Ibn Sina College, Jeddah, Saudi Arabia, ³Umm Al-Qura University, Makkah, Saudi Arabia, ⁴Pharmaceutical Care Department, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
*Purpose: Non-adherence to immunosuppressant therapy (IST) is one of the major factors leading to graft rejection. To our knowledge, limited data exist on the prevalence…