ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Discard Patterns in Donors with Non Alcoholic Fatty Liver Disease

    M. MacConmara1, A. Mufti2, S. Hanish1, P. Vagefi1, S. Tujius2, C. Hwang1

    1Surgery (Division of Surgical Transplantation), UT Southwestern Medical Center, Dallas, TX, 2Medicine (Transplant Hepatology), UT Southwestern Medical Center, Dallas, TX

    *Purpose: Obesity and nonalcoholic fatty liver disease (NAFLD) are major health issues affecting 20-50% of the US adult population and are increasingly prevalent in potential…
  • 2019 American Transplant Congress

    Association of Tacrolimus-Level Variance with De Novo DSA within the First 2 Years after Renal Transplantation

    M. J. Everly1, I. Purnajo1, K. P. Briley2, J. L. Beaumont1, P. Bolin2, S. A. Kendrick3, H. Jones3, K. McLawhorn3, A. Q. Maldonado4, D. Leeser2, C. E. Haisch2, L. M. Rebellato2

    1Terasaki Research Institute, Los Angeles, CA, 2East Carolina University, Greenville, NC, 3Eastern Nephrology Associates, Greenville, NC, 4Vidant Medical Center, Greenville, NC

    *Purpose: Patients that receive an HLA-mismatched kidney transplant (KT) have an increased likelihood to develop de novo DSA (dnDSA). Ideally, immunosuppression is properly adjusted and…
  • 2019 American Transplant Congress

    Prophylactic Use of Eculizumab in Patients at High Risk of Post-Transplant aHUS Recurrence Improves Graft Outcomes

    J. Zuber, S. Caillard, M. Frimat, N. Kamar, P. Gatault, F. Petitprez, M. Louis, V. Chatelet, A. Thierry, D. Bertrand, R. Gaisne, L. Couzi, L. Albano, N. Jourde-Chiche, M. Matignon, J. Bamoulid, C. Pouteil-Noble, M. Peraldi, C. Legendre, E. Rondeau, M. Le Quintrec, V. Frémeaux-Bacchi

    On behalf of the French aHUS Group, France, France

    *Purpose: Eculizumab has revolutionized the management of atypical Hemolytic Uremic Syndrome (aHUS). In 2012, the French aHUS Study Group issued recommendations to advocate the prophylactic…
  • 2019 American Transplant Congress

    Impact of Early Borderline Histological Changes on Subsequent Events in Renal Transplant Recipients

    R. Mehta, S. Tandukar, D. Jorgensen, I. Owoyemi, N. Shah, C. Puttarajappa, C. Wu, S. Hariharan

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The significance of borderline changes suspicious for rejection noted on early renal allograft biopsies on subsequent events in renal transplant recipients is unclear.*Methods: Between…
  • 2019 American Transplant Congress

    Center-Level Variation in HLA-Incompatible Living Donor Kidney Transplantation Outcomes

    K. Jackson1, J. Long1, K. Covarrubias1, J. Motter1, M. Bowring1, J. Chen1, M. Waldram1, B. Orandi2, N. Desai1, A. Massie1, D. Segev1, J. Garonzik-Wang1

    1Johns Hopkins University, Baltimore, MD, 2University of Alabama School of Medicine, Birmingham, AL

    *Purpose: Desensitization protocols for HLA-incompatible living donor kidney transplantation (ILDKT) vary across centers. The impact of these variations, as well as other practice variations, on…
  • 2019 American Transplant Congress

    Vaccine Response as a Predictor of Kidney Transplant Rejection and Serious Infection

    A. Ta'eed, K. R. Polkinghorne, W. R. Mulley

    Department of Nephrology, Monash Health, Clayton, Australia

    *Purpose: Vaccination generates immune memory, including antibodies against harmful pathogens. Transplant immunosuppression prevents similar processes occurring against alloantigens. Transplant recipients have significantly reduced seroresponses to…
  • 2019 American Transplant Congress

    The Impact of Transplant Hospital Organ Procurement on Medicare Cost Report Reimbursement

    E. Y. Zavala1, J. Rogers2

    1Transplant Center, Vanderbilt University Medical Center, Nashville, TN, 2Transplant Management Group, San Diego, CA

    *Purpose: Medicare organ acquisition reimbursement from the Medicare Cost Report includes costs associated with transplant hospitals acquiring an organ for Medicare transplant patients and the…
  • 2019 American Transplant Congress

    Use of Marginal Liver Donors in Pediatric Transplantation: Diverse Profiles of Use in Major Transplant Centers

    C. S. Hwang1, A. Aqul2, A. Mufti3, S. Hanish1, D. Desai1, P. Vagefi1, M. MacConmara1

    1Surgery, UT Southwestern, Dallas, TX, 2Pediatrics, UT Southwestern, Dallas, TX, 3Medicine, UT Southwestern, Dallas, TX

    *Purpose: Pediatric liver transplantation is highly specialized only a small number of centers have consistent large volume experience. We tested the hypothesis that large volume…
  • 2019 American Transplant Congress

    Compatible Pairs in Paired Kidney Exchange – Are There Winners and Loosers?

    V. Chipman1, B. Lee1, M. Cooper2, M. C. Cuffy3, M. Ronin4, G. Hil4, S. Flechner5, A. Thomas6, D. A. Mandelbrot7, A. D. Waterman8, C. E. Freise1, G. R. Roll1

    1UCSF, San Francisco, CA, 2Georgetown Univ, Washington, DC, 3UC Hospital, Cincinnati, OH, 4NKR, Babylon, NY, 5Cleavland Clinic, Cleavland, OH, 6Johns Hopkins, Baltimore, MD, 7Univ of Wisconsin, Madison, WI, 8UCLA and Terasaki Research Institute, Los Angeles, CA

    *Purpose: To understand patterns of participation for compatible pairs and their impact in increasing paired donation in a national registry.*Methods: Favorable pairs (FP) are defined…
  • 2019 American Transplant Congress

    Patient Centered AUC-Monitoring of Tacrolimus Using Capillary Microsampling

    M. T. Gustavsen, K. Midtvedt, N. Vethe, S. Bergan, A. Åsberg

    Oslo University Hospital, Rikshospitalet, Oslo, Norway

    *Purpose: To reduce unwanted side effects of Tacrolimus (Tac), improvement of dosing is warranted. Therapeutic drug monitoring (TDM) of Tac based on trough concentrations (C0)…
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