Am J Transplant, Volume 19, Suppl 3 Archives - Page 13 of 214 - ATC Abstracts

2019 American Transplant Congress
Sequestration of PLIN2 Regulates High-Fat Diet Induced Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in a Mouse Model of Ischemia Reperfusion Injury
K. Loh¹, X. Liu¹, L. Belyayev¹, C. Albanese², W. Cui¹, T. M. Fishbein¹, K. M. Khan¹, A. Kroemer¹
¹Transplant, MedStar Georgetown Transplant Institute, Washington, DC, ²Oncology, Georgetown University, Washington, DC
*Purpose: This study aimed to define characteristics and mechanisms leading to nonalcoholic fatty liver disease and metabolic syndrome in a fatty liver mouse model that…
2019 American Transplant Congress
Immunobiogram, a New IVD Immunoassay to Test the Sensitivity Profile of Kidney Transplant Recipients to Immunosuppressive Drugs: Further Results from BH-Pilot Study
C. Jimenez¹, J. M. Portoles², D. Blánquez³, L. Arribas³, A. Ortega⁴, T. Diez⁵, I. Portero⁶
¹Nephrology Department, La Paz Hospital, Madrid, Spain, ²Nephrology Department, Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, ³Adamas Engineering Consulting, Madrid, Spain, ⁴I+D, Biohope, Madrid, Spain, ⁵Medical, Biohope, Madrid, Spain, ⁶CEO, Biohope, Madrid, Spain
*Purpose: IMBG is an immunoassay developed by Biohope to measure in vitro PBMC sensitivity/resistance profile to a panel of immunosuppressive drugs (IS) in Kidney Transplant…
2019 American Transplant Congress
Pharmacological Enhancement of Bile Duct Preservation and Function during Ex-Situ Normothermic Machine Perfusion
Y. L. Boteon, J. Attard, A. P. Boteon, L. Wallace, G. Reynolds, D. Mirza, H. Mergental, R. Bhogal, S. Afford
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: Whilst ex-situ normothermic machine perfusion (NMP) of the liver limits the ischaemic injury to the organ, benefits for biliary complications post-transplantation are not yet…
2019 American Transplant Congress
Absence of Non Alcoholic Fatty Liver Disease in Allografts from Morbidly Obese Donors: A Marker for Success?
M. MacConmara, A. Mufti, S. Hanish, T. Kerr, P. Vagefi, C. Hwang
Surgery (Division of Surgical Transplantation), UT Southwestern, Dallas, TX
*Purpose: Livers from African-American, morbidly obese donors are less likely to be discarded. We examined the utility of pre-recovery liver biopsy as a predictive biomarker…
2019 American Transplant Congress
Increasing Doses of Pain Medications Pre-Heart Transplant as a Risk Factor for Outcomes after Transplant
K. Shah, D. H. Chang, J. Patel, R. J. Levine, S. Dimbil, E. Passano, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Chronic pain syndromes prior to heart transplantation (HTx) are not uncommon. However, the use of morphine equivalents in higher doses may be indicative of…
2019 American Transplant Congress
First Experience For Cold Storage Of Donor Hearts With Paragonix SherpaPak
L. Stastny¹, M. Kofler¹, D. Höfer¹, G. Pölzl², R. Breitkopf³, M. Grimm¹, H. Antretter¹, J. Dumfarth¹
¹Cardiac Surgery, Medical University Innsbruck, Innsbruck, Austria, ²Internal Medicine, Medical University Innsbruck, Innsbruck, Austria, ³Intensive Care Unit, Medical University Innsbruck, Innsbruck, Austria
*Purpose: Preservation of donor organs is a crucial component for the maintenance of viability after explantation. The current standard for transporting a donor organ includes…
2019 American Transplant Congress
What is the Post-Heart Transplant Risk of Infectious Complications from Pre-Transplant Desensitization Therapy?
E. Kransdorf, J. Patel, S. Dimbil, R. Levine, D. H. Chang, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Sensitization or the detection of circulating antibodies in heart transplant candidates appears to be increasing due to the growing use of mechanical circulatory support…
2019 American Transplant Congress
Temporal Trends Following Uncontrolled Donation after Cardiac Death Kidney Transplantation: Implications for Normothermic Regional Perfusion?
R. A. Choudhury, K. Prins, D. Yoeli, H. B. Moore, T. L. Nydam
Transplant Surgery, University of Colorado, Aurora, CO
*Purpose: Kidney transplantation following uncontrolled donation after cardiac (uDCD) remains an underutilized resource in the United States when compared to controlled DCD (cDCD) which has…
2019 American Transplant Congress
The Kidney Donor Profile Index (KDPI) Predicts the Risk of Graft Loss in Patients with a Kidney Transplant from Maastricht Type III Asystolic Donors
V. Lopez Jimenez, C. Casas, P. Ruiz-Esteban, M. Cabello, E. Sola, P. Hidalgo, J. Alonso, M. González-Molina, D. Hernandez
Nephrology, H.R.U Carlos Haya, Málaga, Spain
*Purpose: Recent years have seen an increase in the number of kidney transplants (KT) from Maastricht type III asystolic donors, resulting in the acceptance criteria…
2019 American Transplant Congress
Outcomes of Renal Transplantation in Elderly Patients Older Than 60 Years of Age
R. Yemini¹, E. Nesher², R. Rahamimov³, S. Eizner², V. Mazhybovsky², V. Tennak², M. Gurevich², R. Ghinea², E. Mor²
¹Department of Surgery, Assuta Ashdod Medical Center, Ashdod, Israel, ²Department of Transplant Surgery, Beilinson Medical Center, Petach-Tikva, Israel, ³Department of Nephrology, Beilinson Medical Center, Petach-Tikva, Israel
*Purpose: Patients ≥ 60 years are the largest growing age group which comprise 40% of all patients with ESRD. Kidney transplantation has been shown to…