Am J Transplant, Volume 19, Suppl 3 Archives - Page 124 of 214 - ATC Abstracts

2019 American Transplant Congress
Absence of Protective Innate Lymphoid Cell Type 3 (ILC3) and Persistence of Proinflammatory Innate Lymphoid Cell Subsets Immediately Post-Transplant Plays a Appreciable Role in Early Intestinal Barrier Dysfunction
J. Kang, L. Belyayev, K. Loh, P. Cha, S. Moturi, K. Khan, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer
Georgetown University, Washington, DC
*Purpose: Innate lymphoid cells (ILCs) , the most recently described family of lymphoid cells, play fundamental roles in mucosal barrier immunity, tissue homeostasis, and immune…
2019 American Transplant Congress
Assessment of the Global Practice of Pediatric Living Donor Liver Transplantation: Comparison of U.S. and International Programs
J. Emamaullee¹, M. Kim¹, C. Conrad¹, C. Lane¹, P. Singh¹, C. Niemann², L. Sher¹, Y. Genyk¹
¹University of Southern California, Los Angeles, CA, ²University of California-San Francisco, San Francisco, CA
*Purpose: As programs have become more experienced with living donor liver transplantation (LDLT), technical hurdles have been overcome and superior graft and patient survival has…
2019 American Transplant Congress
Social Loafing: Distribution of Kidneys with Multiple Renal Arteries in a National Paired Kidney Exchange Program
G. R. Roll¹, W. Irish², M. Cooper³, M. Ronin⁴, G. Hil⁴, A. D. Waterman⁵, D. B. Leeser²
¹UCSF, San Francisco, CA, ²ECU, Greenville, NC, ³Georgetown Univ, Washington, DC, ⁴NKR, Babylon, NY, ⁵UCLA and Terasaki Research Institute, Los Angeles, CA
*Purpose: To describe the distribution and outcomes after kidney transplantation of multiple renal artery kidneys (MRAK) in a national exchange program.*Methods: We retrospectively reviewed donor…
2019 American Transplant Congress
Impact Of Subclinical Bk Virus-associated Nephropathy In High-risk Recipients
M. E. Seifert, E. P. Kasik, M. Bernard, G. Agarwal, H. Fatima, R. Gaston, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, F. Rosenblum, G. Towns, R. B. Mannon
University of Alabama, Birmingham, AL
*Purpose: BK virus-associated nephropathy (BKVAN) is a major contributor to kidney transplant failure. Surveillance of serum and urine for the BKV genome has been incorporated…
2019 American Transplant Congress
Kidney Evaluation in Living Kidney Donors: Survey of US Transplant Centers 2018
N. Garg¹, K. L. Lentine², L. Inker³, A. X. Garg⁴, J. Rodrigue⁵, D. Segev⁶, D. A. Mandelbrot¹
¹UW Madison, Madison, WI, ²SLU, St. Louis, MO, ³Tufts, Boston, MA, ⁴Western University, London, ON, Canada, ⁵BIDMC, Boston, MA, ⁶JHU, Baltimore, MD
*Purpose: In recent years, a great deal of new data has emerged on outcomes after living donation. We surveyed US transplant centers to assess current…
2019 American Transplant Congress
Age-Related Effects on Thymic Output and Homeostatic T Cell Expansion Following Depletional Induction
H. Xu, H. Lee, A. Kirk
Surgery, Duke University, Durham, NC
*Purpose: Alemtuzumab induction leads to profound T cell depletion followed by a prolonged period of repopulation. Repopulation is thought to be influenced both by thymic…
2019 American Transplant Congress
Pre-Transplant Transcriptomic Signature in Peripheral Blood Predicts Early Acute Rejection after Kidney Transplant
W. Zhang¹, Z. Yi¹, C. Wei¹, K. Keung², Z. Sun¹, C. Xi¹, C. Woytovich¹, S. Farouk¹, L. Gallon³, M. Menon¹, C. Magee⁴, N. Najafian⁴, M. Samaniego⁵, A. Djamali⁶, S. Alexander², I. Rosales⁷, R. Smith⁷, P. O'Connell², R. Colvin⁷, P. Cravedi¹, B. Murphy¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²The University of Sydney, Sydney, Australia, ³Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Brigham and Women's Hospital, Boston, MA, ⁵Henry Ford Hospital, Detroit, MI, ⁶University of Wisconsin, Madison, WI, ⁷Massachusetts General Hospital, Boston, MA
*Purpose: Early development of acute rejection after kidney transplantation is associated with diminished long-term graft survival. Predicting early acute rejection (EAR) at the time of…
2019 American Transplant Congress
Differences of Gut Microbiota Composition between Donor and Recipient May Predict 1-Year Graft Function
J. Kim¹, H. Cho², J. Park³, J. Jeong¹, M. Kwak⁴, B. Kim⁴, D. Kim¹, J. Lee⁵, B. Kim⁶, Y. Kim¹, H. Lee¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Chungbuk National University Hospital, Cheongju, Korea, Republic of, ³Kangwon National University Hospital, Seoul, Korea, Republic of, ⁴Chunlab Inc., Seoul, Korea, Republic of, ⁵Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Hallym University, Chuncheon, Korea, Republic of
*Purpose: Signals derived from gut microbiota are critical for the development and maintenance of the human immune system. In view of kidney transplantation (KT), allograft…
2019 American Transplant Congress
Using an Electronic Medical Record Tool to Document Transplant Option Discussions among Patients with EGFR ≤ 20 mL/min/1.73m²
A. Yishak¹, R. R. Brentari², R. M. Love La Londe³, E. Clark⁴, E. Clark⁴, J. Sun⁵, S. Vupputuri⁶
¹Nephrology, MAPMG, Mc Lean, VA, ²KP National Transplant Service, Oakland, CA, ³KP National Transplant Services, Oakland, CA, ⁴KP National Transplant Services, silver spring, MD, ⁵KP, Rockville, MD, ⁶MAPRI, MAPMG, Rockville, MD
*Purpose: The purpose of this study, in a large integrated health system, was to improve: 1) the documentation of transplant option discussions by providers among…
2019 American Transplant Congress
CNI-Free Therapy with Iscalimab (anti-CD40 mAb) Preserves Allograft Histology Compared to Standard of Care after Kidney Transplantation
E. Farkash¹, A. Naik¹, H. Tedesco-Silva², B. Nashan³, O. Witzke⁴, M. van den Hoogen⁵, S. Berger⁶, D. M. Cibrik⁷, S. Mulgaonkar⁸, D. B. Leeser⁹, R. Alloway¹⁰, A. Patel¹¹, J. Pratchke¹², C. Sommerer¹³, A. Wiseman¹⁴, A. Van Zuilen¹⁵, U. Laessing¹⁶, J. Rush¹⁶, B. Haraldsson¹⁶
¹Univ of Michigan, Ann Arbor, MI, ²Hospital do Rim, São Paulo, Brazil, ³Univ. Hamburg, Hamburg, Germany, ⁴Univ Essen, Essen, Germany, ⁵Erasmus MC, Rotterdam, Netherlands, ⁶UMC Groningen, Gröningen, Netherlands, ⁷Univ of Kansas, Kansas City, KS, ⁸Saint Barnabas MC, Livingston, NJ, ⁹East Carolina Univ, Greenville, NC, ¹⁰Univ of Cincinnati, Cincinnati, OH, ¹¹Henry Ford Hosp, Detroit, MI, ¹²Charité Univ, Berlin, Germany, ¹³Univ Heidelberg, Heidelberg, Germany, ¹⁴Univ of Colorado SM, Denver, CO, ¹⁵Univ MC, Utrecht, Netherlands, ¹⁶Novartis, Basel, Switzerland
*Purpose: To assess if calcineurin (CNI)-free therapy with iscalimab preserves the quality of transplanted kidney grafts.*Methods: Iscalimab (CFZ533) is a new, fully human, Fc-silenced, non-depleting,…