Am J Transplant, Volume 19, Suppl 3 Archives - Page 121 of 214 - ATC Abstracts

2019 American Transplant Congress
Poor Outcomes in Kidney Transplant Candidates & Recipients with History of Falls
N. Chu¹, H. Ying¹, Z. Shi¹, C. Haugen¹, S. Norman², D. Segev¹, M. McAdams-DeMarco¹
¹Johns Hopkins, Baltimore, MD, ²Michigan Medical Center, Ann Arbor, MI
*Purpose: In patients with ESRD, serious fall injuries (e.g. fractures) are associated with decreased chance of listing or transplantation. It is likely that KT candidates…
2019 American Transplant Congress
Impact of Donor Hepatitis C Virus Infection on Kidney Transplant Outcomes in the Direct Acting Antiretroviral Era: Time to Revise the KDPI?
R. M. Cannon, E. G. Davis, L. Mackelaite, H. Dave, M. Eng, C. M. Jones
University of Louisville, Louisville, KY
*Purpose: The kidney donor risk index (KDRI), upon which the kidney donor profile index (KDPI) used for renal allocation is based, was derived before the…
2019 American Transplant Congress
Eight-Year Outcomes Following ABO-Incompatible Kidney Transplantation Performed after Desensitization by Antigen-Unspecific Immunoadsorption Devices
C. Speer¹, F. Kälble¹, L. Pego da Silva¹, C. Nusshag¹, M. Schaier¹, C. Süsal², C. Sommerer¹, M. Zeier¹, C. Morath¹
¹Nephrology, University of Heidelberg, Heidelberg, Germany, ²Immunology, University of Heidelberg, Heidelberg, Germany
*Purpose: Owing to the unmet need of available kidney grafts, ABO-incompatible kidney transplantation (KTX) has been established to enlarge the possible donor pool. The current…
2019 American Transplant Congress
Risk Factors for 1-5 Year De Novo Cancers after Kidney Transplant (KTx) with First-Year Immunosuppression (IS) Data: An Analysis of the Choosing Immune Suppression by Efficacy and Morbidity (CISTEM) Study
V. Dharnidharka¹, D. Axelrod², Z. Zhang³, M. Schnitzler³, K. Lentine³, B. Kasiske⁴
¹Washington Univ, St. Louis, MO, ²Univ of Iowa, Iowa City, IA, ³Saint Louis Univ, St. Louis, MO, ⁴SRTR, Minneapolis, MN
*Purpose: From our CISTEM study of linked national registries, we published data on risk factors for within-3-years post-KTx non-melanoma skin cancer (NMSC) and viral-driven cancers…
2019 American Transplant Congress
Microparticle Delivery to Lymph Nodes Induces Specific Suppression to Prolong Islet Survival
Y. Xiong¹, L. Tostanoski², C. Jewell³, J. Bromberg¹
¹Surgery, U. Maryland, Baltimore, MD, ²U.Maryland, Baltimore, MD, ³U. Maryland, College Park, MD
*Purpose: Microparticles (MP) loaded with peptide antigen plus other immune signals and delivered directly into lymph nodes (LN) can result in either proinflammatory or antiinflammatory…
2019 American Transplant Congress
Minimizing Kidney Ischemia Reperfusion Injury by Transferring Exogenous Mitochondria
A. Bajwa¹, V. Bontha¹, J. Eason², D. Maluf³, V. Mas⁴
¹UT, Memphis, TN, ²Director of Transplant Institute. UTHSC, Memphis, TN, ³UTHSC, Memphis, TN, ⁴Director of Transplant Research Institute. UTHSC, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics with increased mitochondrial swelling and reactive oxygen species (ROS) and ultimately degradation of cellular function. Ischemia followed by reperfusion (IRI)…
2019 American Transplant Congress
Multi-Omics Approach to Accurately Assess Early Graft Injury in Liver Transplantation
D. Maluf¹, V. Sai Bontha¹, A. Bajwa¹, R. Helmick¹, P. J. Horton¹, C. Eymard¹, J. Eason², V. Mas³
¹UTHSC, Memphis, TN, ²UTHSC. Director of Transplant Institute, Memphis, TN, ³UTHSC Director Transplant Research Institute, Memphis, TN
*Purpose: We investigated global DNA methylation (DNAm) patterns during ischemia reperfusion (I/R) injury in liver transplant (LT) patients, and their role on regulating gene expression…
2019 American Transplant Congress
The Role of Neutrophil Extracellular Traps in Kidney Acute Antibody-Mediated Rejection
R. Villca-Gonzales¹, J. Torres-Ruiz², D. Gomez-Martin², L. Morales-Buenrostro¹, J. Alberu³
¹Nephrology, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, Mexico, Mexico, ²Immunology, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, Mexico, Mexico, ³Transplantation, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, Mexico, Mexico
*Purpose: Previously our group assessed the spontaneous and lipopolysaccharide-induced NETosis with confocal microscopy in kidney transplant recipients (KTR). We found an enhanced spontaneous NETosis regardless…
2019 American Transplant Congress
Potential Living Kidney Donors’ Interest in Kidney Paired and Non-Directed Donation
D. R. Helfer¹, A. D. Love¹, J. M. Konel¹, J. Stanton², M. G. Bowring¹, K. Kumar¹, S. R. Weeks¹, M. L. Henderson¹, D. L. Segev¹, A. M. Cameron¹, J. M. Garonzik Wang¹
¹Johns Hopkins University, Baltimore, MD, ²East Carolina University, Greenville, NC
*Purpose: Kidney Paired (KPD) and Non-Directed Donation (NDD) are avenues to increase living donation and address organ shortage. We investigated interest in KPD and NDD…
2019 American Transplant Congress
DOME: A New Strategy for Prioritizing Hepatocellular Carcinoma Patients on the Liver Transplant Waitlist
C. Rickert¹, M. Akan², Z. Leung³, J. F. Markmann¹, S. Tayur², H. Zhao³, H. Yeh¹
¹Massachusetts General Hospital, Boston, MA, ²Tepper School of Business, Carnegie Mellon University, Pittsburgh, PA, ³City University of Hong Kong, Hong Kong, China
*Purpose: Currently, adult HCC patients are prioritized for liver transplantation by receiving MELD exception points, determined primarily by time on waitlist without regard to actual…