Am J Transplant, Volume 19, Suppl 3 Archives - Page 12 of 214 - ATC Abstracts

2019 American Transplant Congress
Daratumumab for Treatment of Antibody-Mediated Rejection in a Kidney Transplant Recipient
S. C. Jordan¹, R. Vescio², M. Toyoda³, N. Ammerman¹, E. Huang¹, A. Peng¹, S. Sethi¹, R. Najjar¹, K. Lim¹, A. Vo¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Ctr, Los Angeles, CA, ²Cedars-Sinai Medical Ctr, Los Angeles, CA, ³Transplant Immunology Lab, Cedars-Sinai Medical Ctr, Los Angeles, CA
*Purpose: Antibody-Mediated Rejection (ABMR) is a severe form of rejection mediated by B-cells, plasma cells and antibodies. The consequences to the patients with ABMR are…
2019 American Transplant Congress
Induction Therapy Modulated by the Absence of Preformed Donor-Specific Antibodies (DSAS) Regardless of the Level of Sensitization
M. Cristelli, K. Linhares, R. de Marco, L. Viana, C. Felipe, M. Gaspar, C. Peixoto, G. Marcelo Gomes, J. Toniato Rezende, K. Nunes Ficher, L. Alfaro Villanueva, V. Lima, M. Gerbase de Lima, J. Medina Pestana, H. Tedesco Silva Junior
Núcleo de Ensino e Pesquisa, Hospital do Rim, São Paulo, Brazil
*Purpose: We hypothesized that sensitized patients with preformed DSAs other than anti-HLA A, B, DR could receive less intensive induction therapy.*Methods: Single center retrospective cohort…
2019 American Transplant Congress
Immunologic Impact Of Native Kidney Function On Liver Transplant Patients
M. Mujtaba, S. Merwat, J. Fair, M. Bilal, A. Chatila, R. Kulkarni, J. Zou, S. Hussain, A. Gamilla-Crudo
Univ. of Texas Medical Branch, Galveston, TX
*Purpose: Renal failure in the setting of liver transplantation (LTx) is common and has an adverse impact on short and long-term graft and patient survival.…
2019 American Transplant Congress
Peripheral Blood Regulatory T Cells In The Folow In The Kidney-transplant Patients
M. A. Carmona-Escamilla¹, G. Queipo², L. A. Garcia-Mosqueda³, R. Lascurain⁴
¹Nephrology, Pemex, CDMX, Mexico, ²Genetics, Hospital General, CDMX, Mexico, ³UNAM, CDMX, Mexico, ⁴Inmunologia, UNAM, CDMX, Mexico
*Purpose: Investigate the peripheral blood levels of CD4+CD25+FOXP3p3+ regulatory T cells (Tregs) in patients with kidney transplant at least one year after kidney transplantation and…
2019 American Transplant Congress
In Vivo Treg Expansion under Costimulation Blockade Targets Early Rejection and Improves Long-Term Outcome
C. Schwarz¹, B. Mahr², L. Unger¹, N. Pilat², H. Regele³, T. Wekerle²
¹Dept. of Surg. / Div. of Transplantation, Medical University Vienna, Vienna, Austria, ²Dept. of Surg. / Section of Transplantation Immunology, Medical University Vienna, Vienna, Austria, ³Clinical Institute of Pathology, Medical University Vienna, Vienna, Austria
*Purpose: Early rejection episodes are a major problem under CTLA4Ig/belatacept-based immunosuppression. We have previously shown that CTLA4Ig therapy is dependent on Tregs at low (LD)…
2019 American Transplant Congress
Patterns of Emergency Department (ED) Utilization between Transplant and Non-Transplant Centers and Impact on Clinical Outcomes in Kidney Recipients
H. Perkins, N. Patel, V. Rohan, Z. Su, D. DuBay, J. McGillicuddy, D. Taber
MUSC, Charleston, SC
*Purpose: There is a high rate of ED utilization in kidney recipients post-transplant (txp); ED visits are associated with readmission rates and lower 3-yr survival…
2019 American Transplant Congress
The Changing Paradigm of Ethics in Uterus Transplantation: A Systematic Review
L. M. Ngaage¹, S. Ike², A. Elegbede³, S. Gebran⁴, C. J. Vercler⁵, F. Liang⁴, E. M. Rada¹, C. Cooney³, R. J. Redett³, Y. M. Rasko¹
¹Division of Plastic Surgery, University of Maryland Medical Center, Baltimore, MD, ²London North West University Healthcare Trust, London, United Kingdom, ³Department of Plastic & Reconstructive Surgery, Johns Hopkins Hospital / University of Maryland Medical Center, Baltimore, MD, ⁴Division of Plastic & Reconstructive Surgery, R Adams Cowley Shock Trauma Center, Baltimore, MD, ⁵Plastic Surgery Section, University of Michigan, Ann Arbor, MI
*Purpose: The first uterus transplantation (UTx) was performed in 2000 and sparked ethical debate. As key milestones are reached (successful human UTx in 2011, and…
2019 American Transplant Congress
Evaluation of Mycophenolate Mofetil Exposure in Renal Transplant Recipients
M. C. Ott¹, S. Mietz², S. Chang³
¹Department of Pharmaceutical Services, Erie County Medical Center, Buffalo, NY, ²Department of Pharmacy, Indiana University Health, Indianapolis, IN, ³Department of Medicine, Jacobs School of Medicine & Biomedical Sciencess, Buffalo, NY
*Purpose: Mycophenolate mofetil (MMF) is the most commonly prescribed immunosuppressant following transplantation in the United States. However, the occurrence of MMF therapy-related adverse events including…
2019 American Transplant Congress
Modeling the Effect of Presumed Consent on Waitlist Candidate Quantities
L. DeRoos¹, W. Marrero¹, M. Lavieri¹, D. Hutton², N. Parikh³
¹Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, ²School of Public Health, University of Michigan, Ann Arbor, MI, ³Department of Internal Medicine, University of Michigan, Ann Arbor, MI
*Purpose: Organ transplantation is a life-saving and cost-effective treatment for patients with end-organ failure. However, the current supply of donors is unable to match demand,…
2019 American Transplant Congress
Evaluating Hepatitis C Treatment after Solid Organ Transplantation
A. J. Burgos¹, R. Yau¹, C. Tunwar², J. A. Goss³, S. Khaderi³, N. L. Sussman⁴
¹Pharmacy, CHI St. Luke's Health-Baylor St. Luke's Medical Center, Houston, TX, ²CHI St. Luke's Health-Baylor St. Luke's Medical Center, Houston, TX, ³Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, ⁴Abdominal Transplant & Liver Disease, Baylor College of Medicine, Houston, TX
*Purpose: There is limited data on the use of direct acting antivirals for hepatitis C virus (HCV) in the solid organ transplant (SOT) population. The…