Am J Transplant, Volume 19, Suppl 3 Archives - Page 12 of 214 - ATC Abstracts

2019 American Transplant Congress
Pre-emptive Ivig For Dsa Positive Living Donor Kidney Transplant Recipients
B. Abdalla¹, D. Kellner², A. Diaz², Y. Zheng³, E. Reed⁴, Q. J. Zhang⁴
¹Medicine, Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ²David Geffen School of Medicine at UCLA, Los Angeles, CA, ³UCLA Immunogenetics Center, Los Angeles, CA, ⁴Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: Intravenous immunoglobulin (IVIG) is used in desensitization regimens to modulate anti-human leukocyte antigen (HLA) donor-specific antibody (DSA) to facilitate transplantation of sensitized patients, however,…
2019 American Transplant Congress
Policy Changes in Liver Graft Allocation for Hepatocellular Carcinoma in the USA: Improved Survival for African American Recipients
M. Molinari¹, D. Jorgensen¹, A. Tevar¹, C. Hughes¹, A. Humar¹, N. Jonassaint²
¹Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, ²Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA
*Purpose: To evaluate the effect of policy changes in liver graft allocation for hepatocellular carcinoma (HCC) on the overall survival of patients of different ethnicities…
2019 American Transplant Congress
Karnofsky Performance Score as a Predictor of Acute Cellular Rejection Post Liver Transplantation
N. Kapila¹, K. Al Khalloufi², F. Salomon³, K. Kapila⁴, A. Gupta³, X. B. Zervos²
¹Gastroenterology and Hepatology, Cleveland Clinic Florida, Weston, FL, ²Transplant, Cleveland Clinic Florida, Weston, FL, ³Internal Medicine, Cleveland Clinic Florida, Weston, FL, ⁴Internal Medicine, University of Miami/JFK Medical Center, Atlantis, FL
*Purpose: The incidence of acute cellular rejection (ACR) following liver transplantation (LT) ranges from 20-40%. Development of ACR is associated with increased risk of graft…
2019 American Transplant Congress
CD4 T Cell is Essential in an Innate-Immune Driven Ischemia-Reperfusion Injury in Mouse and Human
S. Kageyama¹, K. Kadono¹, H. Hirao¹, K. Nakamura¹, T. Ito², K. J. Dery¹, D. Oncel¹, R. A. Sosa³, E. F. Reed³, F. M. Kaldas², R. W. Busuttil², J. W. Kupiec-Weglinski¹, Y. Zhai¹
¹Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA, ²Surgery, Ronald Reagan UCLA Medical Center, Los Angeles, CA, ³Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA
*Purpose: Although CD4 T cells are critical in the mechanism of allograft rejection, little is known about their role in the innate immune-driven ischemia-reperfusion injury…
2019 American Transplant Congress
Prolonged Cold Ischemic Storage Induces Allograft Necro-Inflammation That Increases Graft Susceptibility to T Cell Mediated Rejection
N. Chun¹, R. Ang¹, J. Horwitz¹, R. Fairchild², W. Baldwin III², A. Ting¹, P. S. Heeger¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²Cleveland Clinic, Cleveland, OH
*Purpose: Prolonged cold ischemic storage (CIS) of murine cardiac allografts causes complement dependent, CTLA4Ig-resistant rejection that is associated with 48h post-transplant elevations in serum levels…
2019 American Transplant Congress
Variations in Recipient and Donor Clinical Characteristics between Kidney Transplant Centers
W. T. McKinney¹, M. Bruin², S. Chu², D. Schladt³, J. Snyder³, A. Matas⁴, B. Kasiske⁵, A. K. Israni³
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²College of Design, University of Minnesota, St. Paul, MN, ³Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN, ⁵Department of Medicine, Hennepin Healthcare, Minneapolis, MN
*Purpose: When a patient can choose at which kidney transplant program to establish care, prior knowledge of program acceptance practices (of candidates and donors) can…
2019 American Transplant Congress
How Much Does Graft Function Cost Us? A Financial Analysis of Delayed Graft Function in Kidney Transplant Recipients
A. Yaldo, I. Bajjoka, C. Crombez, M. Abouljoud
Henry Ford Transplant Institute, Detroit, MI
*Purpose: Kidney transplant recipients (KTR) who receive dialysis post-transplant experience worse outcomes during the first year post-transplant. Whether KTR discharged with elevated levels of serum…
2019 American Transplant Congress
Clinical Utility of a Pharmacogenomic Testing Tool among Kidney Transplant Recipients
S. LeCorchick, L. Lindberg, W. Stapley, S. Anand, D. Morris, T. Srinivas
Kidney/Pancreas Transplant Program, Intermountain Medical Center, Murray, UT
*Purpose: Therapeutic drug monitoring (TDM) for tacrolimus (Tac) is the cornerstone of clinical workflow in the transplant clinic. We report on the clinical implementation of,…
2019 American Transplant Congress
A Pilot Study of Organ Donor Registration among Persons Living with HIV (PLWH)
D. Bhamidipati¹, P. Veldkamp², L. Despines¹, C. Sullivan³, S. Stuart³, D. McMahon², G. Haidar²
¹UPMC, Pittsburgh, PA, ²Division of Infectious Diseases, UPMC, Pittsburgh, PA, ³Center for Organ Recovery and Education, Pittsburgh, PA
*Purpose: Under the HIV Organ Policy Equity Act (HOPE Act), persons living with HIV (PLWH) may receive organ transplants from HIV-infected donors. However, awareness of…
2019 American Transplant Congress
Excellent Success with Safety and Efficacy of Direct-Acting Anti-Viral HCV Drugs in Kidney Transplant Recipients Using an Evolving Regimen. A Single Institution Experience
A. Sharfuddin, S. A. Hussain, T. Taber, D. Mishler, O. Adebiyi, M. S. Yaqub
Indiana University School of Medicine, Indianapolis, IN
*Purpose: Chronic Hepatitis C Virus (HCV) infection has a negative impact on graft survival. Prior treatments were poorly tolerated and had minimal cure rates. We…