Am J Transplant, Volume 19, Suppl 3 Archives - Page 118 of 214 - ATC Abstracts

2019 American Transplant Congress
Comparison of Initial Sirolimus (SRL) and Everolimus (EVR) Exposure Patterns in Kidney Transplant Recipients
C. Rosso Felipe, L. Viana, M. Pontello Cristelli, M. Nakamura, L. Ramagnoli, S. Braga, V. Lima, A. Carnevalle, D. Casarini, J. Medina Pestana, H. Tedesco Silva Junior
Hospital do Rim, Nephrology Division, EPM - UNIFESP, São Paulo, Brazil
*Purpose: Despite distinct pharmacokinetic properties, SRL and EVR bind to the same intracellular target protein, suggesting that equivalent blood concentrations may exert similar pharmacodynamic effect.*Methods:…
2019 American Transplant Congress
Illustration of Renal Recovery in SLK with Utilization of Most Recent Allocation Criteria
B. Patel, R. Prashar, A. Babu
Henry Ford Hospital Detroit, Detroit, MI
*Purpose: Single Center review of Renal recovery in Simultaneous Liver Kidney Transplantation (SLKT) in patients who were approved for SLK based on the recent UNOS…
2019 American Transplant Congress
Comparable Outcomes of Deceased Donor Liver Transplant Outcomes in Recipients with Previous Abdominal Surgery (PAS) after Pre Listing Surgical Categorization. A Propensity-Score Matched Pair Analysis
H. Sharma, H. Bohorquez, D. Oganesyan, D. Bruce, E. Bugeaud, I. Carmody, A. Cohen, J. Seal, D. Sonnier, G. Loss
Department of Transplant Surgery, Ochsner Medical Center, New Orleans, LA
*Purpose: Few studies have evaluated the impact of previous abdominal surgery (PAS) on deceased donor liver transplantation-(DDLT). Furthermore, there is no evidence of impact of…
2019 American Transplant Congress
Use of a CMV Specific T Cell Immunity Assay in Late-Onset CMV Infection
O. Beaird¹, M. Carlson¹, P. Gaynor¹, D. Nanayakkara¹, B. Abdalla², S. Bunnapradist², J. Schaenman¹
¹Department of Internal Medicine - Division Infectious Diseases, UCLA, Los Angeles, CA, ²Department of Internal Medicine - Division Nephrology, UCLA, Los Angeles, CA
*Purpose: To describe our clinical experience using a CMV Specific Cell Mediated Immunity (CMI) assay in solid organ transplant (SOT) recipients with late-onset CMV, defined…
2019 American Transplant Congress
Profile of Invasive Fungal Disease after Kidney Transplantation in a Single Brazilian Center
S. C. Miranda, G. M. Pereira Junior, C. A. Felipe, A. S. Alvarenga, P. A. Macedo Souza, C. Ribeiro, S. C. Cantini
Nephrology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil
*Purpose: This study sought to describe the epidemiology of Invasive fungal disease at a brazilian kidney transplant center.*Methods: We retrospectively evaluated the diagnoses of invasive…
2019 American Transplant Congress
Treatment of Pseudomonas Infection with Beta-Lactams Including Ceftolozane-Tazobactam in Solid Organ Transplant Recipients
M. Henry¹, J. Puvvula², J. John Schoen¹, L. Puzniak³, J. Raddatz⁴, T. Van Schooneveld², S. Bergman¹
¹Nebraska Medicine, Omaha, NE, ²University of Nebraska Medical Center, Omaha, NE, ³Merck & Co., Inc, Kenilworth, NJ, ⁴Merck & Co., Inc, Kenilworth, NJ, NJ
*Purpose: Ceftolozane/Tazobactam (CT) is a potent anti-pseudomonal agent with broad gram-negative activity. Our academic medical center recommends the use of CT for patients with a…
2019 American Transplant Congress
Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation
H. Zheng, Y. Su, C. Zhu, V. Veramkovich, X. Zheng
Pathology, University of Western Ontario, London, ON, Canada
*Purpose: This study aims to discover new molecular mechanisms involved in and to develop new treatment for preventing ischemia reperfusion injury in heart transplantation.*Methods: The…
2019 American Transplant Congress
Stabilization of Cell Junctions Ameliorates the Effects of Brain Death Induced Acute Lung Injury Post-Transplantation
D. P. Allen¹, Z. Tu¹, C. Wallace¹, C. Li¹, J. Kilkenny¹, K. J. Patel¹, D. Nord², S. N. Nadig¹, C. Atkinson²
¹Surgery, Medical University of South Carolina, CHARLESTON, SC, ²Microbiology & Immunology, Medical University of South Carolina, CHARLESTON, SC
*Purpose: Donor Brain death (BD) induces acute lung injury (BD-ALI), characterized by the breakdown of endo/epithelial barrier functions. These injuries are further exacerbated by ischemia…
2019 American Transplant Congress
A Robust and Portable Protocol for RNA Isolation from Urinary Cells for Noninvasive Monitoring of Kidney Allograft Recipients
B. Botticelli, S. Albakry, E. Edusei, H. Yang, M. Cassidy, C. Li, C. Snopkowski, M. Lubetzky, J. Lee, D. Dadhania, T. Muthukumar, M. Suthanthiran
Weill Cornell, New York, NY
*Purpose: Urinary cell mRNA abundance, assessed by RT-qPCR assay, is a robust monitoring tool. In the CTOT-04 study, urine processed by 5 transplant sites were…
2019 American Transplant Congress
Development of De Novo DSA after Kidney Transplant Correlates with Low Quantity of Peripheral Blood “Antibody-Suppressor” CD8⁺T Cells
J. Zimmerer¹, M. Basinger¹, B. Ringwald¹, R. Pelletier¹, A. Rajab¹, A. El-Hinnawi¹, M. Abdel-Rousoul², H. Parekh³, K. Washburn¹, G. Bumgardner¹
¹Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, ²Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, OH, ³Clinical Histocompatibility Laboratory, The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: It is well known that CD4+ T cells provide “help” for antibody production in vivo. Our group discovered a novel subset of murine antibody-suppressor…