Am J Transplant, Volume 19, Suppl 3 Archives - Page 114 of 214 - ATC Abstracts

2019 American Transplant Congress
ICOS⁺PD-1⁺ Circulating T Follicular Helper Cells Are a Biomarker of Humoral Alloreactivity and Predict Donor-Specific Antibody Generation Following Transplantation
G. M. La Muraglia II, M. E. Wagener, M. L. Ford, I. R. Badell
Emory Transplant Center, Atlanta, GA
*Purpose: Mounting evidence in kidney transplantation suggests that donor-specific antibodies (DSA) significantly contribute to renal allograft loss. However, biomarkers to guide clinical management of DSA…
2019 American Transplant Congress
Donor-Recipient HLA Mismatched Peptides Calculated by PIRCHE Algorithm Associate with De Novo Donor-Specific Cellular and Humoral Alloreactivity and Predicts Inferior Graft Outcome
M. Meneghini¹, E. Crespo², M. Niemann³, A. Torija², E. Melilli⁴, M. Jarque², N. Montero⁴, J. Cruzado¹, J. Grinyo¹, O. Bestard¹
¹Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, ²Experimental Nephrology Laboratory, IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, ³PIRCHE AG, Berlin, Germany, ⁴Kidney Transplantation Unit, Bellvitge University Hospital, L'Hospitalet de Llobregat. Barcelona, Spain
*Purpose: PIRCHE-II algorithm predicts mismatched donor-derived HLA peptides number presented on recipient HLAclass-II molecules to recipient T-cells (indirect pathway of allorecognition) and has been associated…
2019 American Transplant Congress
Association between Recipient Sex and Risk of Heart Graft Failure
A. Chackowicz¹, X. Zhang², M. Dahhou², R. Sapir-Pichhadze³, H. Cardinal⁴, B. Foster⁵
¹Faculty of Medicine, McGill University, Montreal, QC, Canada, ²Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³Dept. of Medicine, McGill University, Montreal, QC, Canada, ⁴Dept. of Medicine, Université de Montréal, Montreal, QC, Canada, ⁵Dept. of Pediatrics, McGill University, Montreal, QC, Canada
*Purpose: Previous studies of sex differences in heart transplant outcomes focused on interactions between donor and recipient sex, but did not consider the potentially modifying…
2019 American Transplant Congress
Anemia and Hemolysis on Dapsone Despite Normal Glucose-6-Phosphate Dehydrogenase Activity in Heart Transplant Recipients
K. Lor, E. Kransdorf, J. Patel, M. Kittleson, D. Chang, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Dapsone has been considered an acceptable alternative for pneumocystis jirovecii pneumonia (PCP) prophylaxis in sulfa-allergic or -intolerant transplant patients with normal glucose-6-phosphate dehydrogenase (G6PD)…
2019 American Transplant Congress
Cardioprotective Effects of Pre-Operative Cyclosporine in Patients Undergoing Heart Transplantation
Y. Hirase, M. Harris, M. Watson, H. Lee, C. Patel
Duke University Hospital, Durham, NC
*Purpose: The purpose of this study is to determine if pre-operative cyclosporine (Cya) decreases the rate of primary graft dysfunction (PGD) in patients undergoing orthotopic…
2019 American Transplant Congress
Kidney Donor Profile Index Significantly Correlates With Reperfusion Biopsy Findings
A. Perez-Gutierrez¹, P. Witkowski¹, J. Fung¹, D. N. Danz², R. Cummings¹, A. Chang³
¹Transplantation Institute, University of Chicago Medicine, Chicago, IL, ²Economics, University of Pittsburgh, Pittsburgh, PA, ³Pathology, University of Chicago Medicine, Chicago, IL
*Purpose: The kidney donor profile index (KDPI) includes donor factors that are associated with graft survival, and estimates the quality of the kidney graft. Suboptimal…
2019 American Transplant Congress
Renal Allograft Survival after Dual Kidney Transplantation is at Least as Favorable as Outcome after Expanded Criteria Donor Kidney Transplantation
A. Brar¹, M. Sattar¹, A. Gruessner¹, R. M. Jindal², R. Nee³, R. Gruessner¹, M. Salifu¹
¹SUNY Downstate Medical Center, Brooklyn, NY, ²Department of Surgery,, USU-Walter Reed Uniformed Services University, Bethesda, MD, ³USU-Walter Reed Uniformed Services University, Bethesda, MD
*Purpose: Dual kidney transplantation (DKT) is the implantation of two adult kidneys from a marginal donor into a single recipient. DKT may play an important…
2019 American Transplant Congress
Kidney Transplants Following Donation after Circulatory Death and Donation after Brain Death Have Similar Early Outcomes
M. Hobeika¹, D. Nguyen², E. Graviss², A. Gaber¹, H. Podder¹, S. Yi¹, S. Kuten³, S. Patel³, R. Knight¹
¹J.C. Walter, Jr. Transplant Center, Houston Methodist Hospital, Houston, TX, ²Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Houston, TX, ³Pharmacy, Houston Methodist Hospital, Houston, TX
*Purpose: Donation after circulatory death (DCD) is common in the US, comprising 18.3% of the deceased donor pool in 2017. Recipient outcomes following DCD kidney…
2019 American Transplant Congress
Desensitization Using Only Polyvalent Immunoglobulins (IVIG) for Kidney Transplantation with Living Donors (LD)
L. R. Ulisses, J. O. Paixão, P. S. Souza, G. Bezerra, H. Rodrigues, N. Panajatopoulos, F. J. De Paula, E. David-Neto, M. C. R Castro
Renal Transplant Service, Renal Transplant Service, Hospital das Clinicas and Laboratory of Immunology-LIM-19, Medical School of te University of São Paulo, São Paulo, Brazil, São Paulo, Brazil
*Purpose: HLA sensitization is a barrier for kidney transplantation. Sensitized patients stay longer on the waiting list and have higher mortality rate and complications while…
2019 American Transplant Congress
Thymoglobulin Versus Alemtuzumab Induction in High Immunologic Risk Kidney Transplants
J. Lockridge¹, J. Pryor¹, D. Norman¹, A. Olyaei²
¹OHSU, Portland, OR, ²Pharmacy, OHSU, Portland, OR
*Purpose: The optimal induction immunosuppressive therapy to prevent kidney transplant rejection remains controversial, specifically among high immunologic risk patients. Our aim was to compare the…