ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Long-Term Exposure to Particulate Matter Air Pollution and the Risk of Graft Failure and Mortality in Kidney Transplant Recipients

    Y. Kim1, S. Kwon1, J. Park2, J. Lee3

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea, Republic of, 3Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea, Republic of

    *Purpose: Elevated levels of fine particulate matter, 10 μm in aerodynamic diameter (PM10) are associated with increased risk of cardiovascular outcomes and death, but their…
  • 2019 American Transplant Congress

    Broadly Profiling the Activation Status of Circulating Immune Cells in Chronic Active Antibody Mediated Rejetion Reveals Increased CD38 and CD16 Expression on Monocytes and NK Cells

    K. Sablik, N. Litjens, M. Klepper, M. Betjes

    Erasmus MC, Rotterdam, Netherlands

    *Purpose: Chronic-active antibody mediated rejection (c-aABMR) contributes significantly to late renal allograft failure. Non-invasive biomarkers of c-aABMR are currently not available but could be valuable…
  • 2019 American Transplant Congress

    HuR Dictates HO-1 Expression, Modulates Inflammation and Influences Recipient Outcomes in Liver Transplant Patients

    K. J. Dery, K. Nakamura, K. Kadono, H. Hirao, S. Kageyama, T. Ito, J. Aziz, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski

    Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA

    *Purpose: Liver ischemia-reperfusion injury, an innate-immune dominated hepatocellular damage, is a risk factor of early graft dysfunction and rejection in liver transplantation (LT). HuR, an…
  • 2019 American Transplant Congress

    Combined Pre-Transplant Anti-Donor T-Cell Sensitization with Single Nucleotid Polimorphisms (SNPs) for CYP3A4 Tacrolimus Metabolism Identifies Kidney Transplant Patients at High Risk of Allograft Rejection

    E. Crespo1, A. Vidal1, A. Sefrin2, P. Fontova1, M. Stein2, H. Volk2, J. Grinyó3, P. Reinke2, N. Lloberas1, O. Bestard3

    1Experimental Nephrology Laboratory, IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, 2Nephrology, Charité Campus Virchow-Klinikum, Berlin, Germany, 3Kidney Transplant Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain

    *Purpose: Preformed donor-specific (d-sp) T-cell alloimmunity has been associated to high risk of acute rejection (BPAR). Since the individual susceptibility related to specific single nucleotide…
  • 2019 American Transplant Congress

    3-year Outcome Of Heart Transplantation In Patients With Amyloidosis

    J. Patel, M. Kittleson, D. H. Chang, R. Levine, S. Dimbil, L. Czer, F. Esmailian, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid are expanding indications for heart transplantation (HTx). In the past, AL amyloid, in particular,…
  • 2019 American Transplant Congress

    Slowed Progression of Maximal Intimal Thickening by Intravascular Ultrasound after Initiation of Sirolimus

    A. Putschoegl1, K. Campbell1, M. Everitt1, S. Miyamoto1, B. Pietra2, S. Auerbach1

    1Children's Hospital Colorado, Aurora, CO, 2University of Florida Health, Gainesville, FL

    *Purpose: Evidence in adult heart transplant (HT) patients (pt) shows that initiating sirolimus (SRL) slows progression of cardiac allograft vasculopathy (CAV) measured by intravascular ultrasound…
  • 2019 American Transplant Congress

    Impact of Donor Acute Kidney Injury on GFR at 1 Year

    R. Heilman, A. Kumar, A. Srinivasan, M. Smith, J. Huskey, H. Khamash, A. Mathur, C. Jadlowiec, A. Moss, K. S. Reddy

    Mayo Clinic, Phoenix, AZ

    *Purpose: GFR 1-year after kidney transplantation is a marker for long term graft survival. The aim of this study is to determine the impact of…
  • 2019 American Transplant Congress

    Racial Differences in Acute Kidney Injury Occurrence among Deceased Kidney Donors

    M. Doshi1, I. Hall2, S. Mohan3, C. Liu4, H. Philbrook4, P. Reese5, S. Mansour6, F. Weng7, E. Akalin8, J. Bromberg9, M. Harhay10, T. Muthukumar11, B. Schroeppel12, P. Singh13, C. Parikh4

    1University of Michigan, Ann Arbor, MI, 2University of Utah, Salt Lake City, UT, 3Columbia, New York, NY, 4Johns Hopkins, Baltimore, MD, 5University of Pennsylvania, Philadelphia, PA, 6Yale University, New Haven, CT, 7St. Barnabas, Livingston, NJ, 8Mount Sinai, New York, NY, 9University of Maryland, Baltimore, MD, 10Drexel, Philadelphia, PA, 11Cornell, New York, NY, 12University of Ulm, Ulm, Germany, 13Jefferson, Philadelphia, PA

    *Purpose: Kidneys from African American (AA) deceased donors have lower graft survival than kidneys from white donors, regardless of recipient race. We hypothesized that kidneys…
  • 2019 American Transplant Congress

    A Retrospective Analysis Evaluating Various Tissue Biopsy Scoring Systems in Predicting Recipient Outcomes Following Transplantation of Extended Criteria Donor Kidneys

    A. Hijazi1, D. Nap1, M. Gabril2, M. Moussa2, V. Ibrahim3, M. A. Levine4, M. Madruah4, P. Luke4, A. Sener4

    1Schulich School of Medicine and Dentistry, London, ON, Canada, 2Pathology, London Health Sciences Center, London, ON, Canada, 3Western University, London, ON, Canada, 4Urology, London Health Sciences Center, London, ON, Canada

    *Purpose: Organ selectivity for transplantation can be quite challenging, especially for marginal kidneys. We examined the prognostic utility of the Maryland Aggregate Pathology Index (MAPI)…
  • 2019 American Transplant Congress

    Successful Use of Nonantigen Specific Immunoadsorption In ABO-Incompatible Desensitization and Humoral Rejection Treatment in Kidney Transplantation

    E. Montagud-Marrahi

    Servei de Nefrologia i Trasplantament Renal, Hospital Clínic de Barcelona, Barcelona, Spain

    *Purpose: : Immunoadsorption (IA) is an apheresis procedure that has been shown to be effective in the ABO incompatible living donor kidney transplantation (ABOi LDKT)…
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