ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Opioid and Benzodiazepine Use in Lung Transplant Candidates: A National Survey of Policies and Practices

    H. Bruschwein1, V. Andersen1, H. Patel2, J. Fleming3, A. Shahane1, M. Weder1

    1University of Virginia, Charlottesville, VA, 2University of North Carolina, Chapel Hill, NC, 3Medical University of South Carolina, Charleston, SC

    *Purpose: The opioid epidemic has raised the question of how transplant teams should work with patients who are prescribed opioids. Benzodiazepine use has also received…
  • 2019 American Transplant Congress

    Butyrate-Producing Gut Bacteria and Future Development of Viral Infections in Kidney Transplant Recipients

    J. Lee1, J. Huang1, M. Magruder1, L. Zhang1, M. Lubetzky1, D. Dadhania1, E. Edusei1, E. Pamer2, M. Suthanthiran1

    1Weill Cornell Medicine, New York, NY, 2Memorial Sloan Kettering Cancer Center, New York, NY

    *Purpose: Recent studies suggest that the gut microbiome plays a critical role in protecting its host from infections beyond Clostridium difficile. Notably, butyrate-producing bacteria may…
  • 2019 American Transplant Congress

    Kidney Transplant Outcomes and Organ Acceptance Practice Patterns: Nationwide Analyses of the US and France

    O. Aubert1, P. P. Reese2, Y. Bouatou1, M. Raynaud1, C. Legendre1, D. Glotz1, C. Lefaucheur1, C. Jacquelinet3, A. Loupy1

    1Paris Translational Center for Organ Transplantation, Paris, France, 2Department of Medicine, Renal-Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA, 3Agence de la Biomédecine, Paris, France

    *Purpose: Approximately 3,500 donated kidneys are discarded in the US each year, drawing concern from Medicare and advocacy groups. We hypothesised that more aggressive organ…
  • 2019 American Transplant Congress

    Infectious Complications of Eculizumab Use in Abdominal Organ Transplant Recipients

    A. M. Nolan1, E. J. Fraser2, H. K. Grewal3, J. G. Timpone3

    1Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC, 2Georgetown University School of Medicine, Washington, DC, 3Division of Infectious Diseases and Travel Medicine, Medstar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study is to identify and characterize infections in abdominal organ transplant recipients related to treatment with eculizumab. Eculizumab (Soliris®) is…
  • 2019 American Transplant Congress

    Tertiary Lymphoid Organs in Renal Chronic Allograft Rejection

    K. Abou-Daya, D. Zhao, A. Williams, M. Oberbarnscheidt

    Starzl Transplantation Institute, Pittsburgh, PA

    *Purpose: Chronic allograft rejection remains a major obstacle to long-term allograft survival. Tertiary lymphoid organs (TLOs) are ectopic lymphoid structures that arise in non-lymphoid tissues…
  • 2019 American Transplant Congress

    CD46 Transgene Modification and Thrombosis in Neonatal Porcine Islet Xenotransplantation

    M. Song, K. Samy, Q. Gao, R. P. Davis, F. Leopard, Z. Fitch, C. Bennett, G. R. Devi, B. H. Collins, A. D. Kirk

    Surgery, Duke University, Durham, NC

    *Purpose: Vascular thrombosis activation is an important cause for early xeno-islet loss. To better understand the thrombosis process in islet xenotransplantation and the effect of…
  • 2019 American Transplant Congress

    The Collaborative Improvement and Innovation Network (COIIN): Impact on Deceased Donor Transplant Rates and Offer Acceptance Practices

    A. Wey1, S. Gustafson1, B. Carrico2, J. Foutz2, K. Sisaithong3, M. McBride2, D. Klassen2, D. Klassen2, N. Salkowski1, B. Kasiske1, A. Israni1, J. Snyder1

    1SRTR, Minneapolis, MN, 2OPTN, Richmond, VA, 3OPTN, Minneapolis, MN

    *Purpose: The Organ Procurement and Transplantation Network (OPTN) completed the Collaborative Improvement and Innovation Network (COIIN), a study to increase kidney transplants by reducing risk…
  • 2019 American Transplant Congress

    How Do We Choose? Predicting Utilization Of Cardiac Donors And The Effect Of Era

    D. A. Baran1, J. T. Lansinger2, A. Long2, J. Philpott3, H. Copeland4, W. Old3, G. Zeevi3, C. Barreiro3, C. Kemp3, B. H. Smith3, K. Stelling3, A. Ingemi3, P. Bourassa3, J. M. Herre3

    1Sentara Heart Hospital, Virginia Beach, VA, 2Eastern Virginia Medical School, Norfolk, VA, 3Sentara Heart Hospital, Norfolk, VA, 4University of Mississippi Medical Center, Jackson, MS

    *Purpose: The number of patients on the heart transplant waitlist continues to rise. However, the rate of organ acceptance is only about 1/3 of all…
  • 2019 American Transplant Congress

    Clazakizumab as an Agent to Reduce Donor Specific HLA Antibodies and Improve Outcomes in Patients with Chronic & Active Antibody-Mediated Rejection Post-Kidney Transplantation

    S. C. Jordan1, N. Ammerman1, M. Toyoda2, E. Huang1, C. C. Nast3, A. Peng1, S. Sethi1, R. Najjar1, I. Kim1, K. Lim1, J. Choi1, A. Vo1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Ctr, Los Angeles, CA, 2Transplant Immunology Lab, Cedars-Sinai Medical Ctr, Los Angeles, CA, 3Department of Pathology, Cedars-Sinai Medical Ctr, Los Angeles, CA

    *Purpose: Highly sensitized (HS) patients are at an increased risk for chronic antibody mediated rejection (cABMR) and graft loss due to persistent, deleterious DSA production.…
  • 2019 American Transplant Congress

    Letermovir For The Treatment And Secondary Prophylaxis Of Drug Resistant CMV In Solid Organ Transplant Recipients

    M. R. Pereira1, J. G. Aaron1, C. J. Kubin2

    1Medicine - Infectious Diseases, Columbia University Medical Center, New York, NY, 2Medicine - Infectious Diseases, NewYork Presbyterian Hospital, New York, NY

    *Purpose: Although only approved for primary prophylaxis of CMV among allogeneic stem cell transplant recipients, there is great interest in the use of letermovir (LET)…
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