ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Estimated vs. Actual Graft Failure and Patient Survival after Kidney Transplantation

    J. Buggs1, T. Thigpen2, E. Rogers1, A. Kumar3, V. Bowers1

    1Tampa General Hospital, Tampa, FL, 2Wesleyan College, Macon, GA, 3University of South Florida, Tampa, FL

    *Purpose: The purpose of this study was to examine the difference between the estimated and actual values of graft survival and patient survival in kidney…
  • 2019 American Transplant Congress

    The Effect of a Novel Dosing Protocol for the De Novo Use of LCP Tacrolimus in Kidney Transplant Recipients Managed on a Steroid-Free Maintenance Immunosuppression Regimen

    R. Wolff1, A. Nasstrom1, C. Borscheid1, C. Martin1, A. Temelie1, R. Spong2, D. Keys2, T. B. Dunn3

    1School of Pharmacy, MHealth U of MN Medical Center-Fairview, Mpls, MN, 2Medicine, MHealth U of MN Medical Center-Fairview, Mpls, MN, 3Surgery, U of Pennsylvania, Phila, PA

    *Purpose: It is not known if an extended release formulation of tacrolimus (LCPT, Envarsus XR®) can be successfully dosed to achieve an early therapeutic trough…
  • 2019 American Transplant Congress

    Assessment of Proteinuria Reported as Adverse Events in De Novo Renal Transplant Recipients Receiving an Everolimus-Based Regimen: 24-Month Results from TRANSFORM

    C. Legendre1, S. Berger1, F. Oppenheimer1, A. Wiseman1, S. Steinberg1, O. Viklicky1, G. Russ1, R. Danguilan1, N. Basic-Jukic1, E. Mor1, P. Narvekar2, M. P. Hernandez Gutierrez2, P. Bernhardt2, C. Sommerer1

    1TRANSFORM Study Group, Basel, Switzerland, 2Novartis Pharma AG, Basel, Switzerland

    *Purpose: mTOR inhibitors (eg, everolimus [EVR]), are thought to increase the risk of post-transplant (Tx) proteinuria (PU). Here, we assess PU onset and outcomes in…
  • 2019 American Transplant Congress

    Comparison of Initial Sirolimus (SRL) and Everolimus (EVR) Exposure Patterns in Kidney Transplant Recipients

    C. Rosso Felipe, L. Viana, M. Pontello Cristelli, M. Nakamura, L. Ramagnoli, S. Braga, V. Lima, A. Carnevalle, D. Casarini, J. Medina Pestana, H. Tedesco Silva Junior

    Hospital do Rim, Nephrology Division, EPM - UNIFESP, São Paulo, Brazil

    *Purpose: Despite distinct pharmacokinetic properties, SRL and EVR bind to the same intracellular target protein, suggesting that equivalent blood concentrations may exert similar pharmacodynamic effect.*Methods:…
  • 2019 American Transplant Congress

    Illustration of Renal Recovery in SLK with Utilization of Most Recent Allocation Criteria

    B. Patel, R. Prashar, A. Babu

    Henry Ford Hospital Detroit, Detroit, MI

    *Purpose: Single Center review of Renal recovery in Simultaneous Liver Kidney Transplantation (SLKT) in patients who were approved for SLK based on the recent UNOS…
  • 2019 American Transplant Congress

    Comparable Outcomes of Deceased Donor Liver Transplant Outcomes in Recipients with Previous Abdominal Surgery (PAS) after Pre Listing Surgical Categorization. A Propensity-Score Matched Pair Analysis

    H. Sharma, H. Bohorquez, D. Oganesyan, D. Bruce, E. Bugeaud, I. Carmody, A. Cohen, J. Seal, D. Sonnier, G. Loss

    Department of Transplant Surgery, Ochsner Medical Center, New Orleans, LA

    *Purpose: Few studies have evaluated the impact of previous abdominal surgery (PAS) on deceased donor liver transplantation-(DDLT). Furthermore, there is no evidence of impact of…
  • 2019 American Transplant Congress

    Use of a CMV Specific T Cell Immunity Assay in Late-Onset CMV Infection

    O. Beaird1, M. Carlson1, P. Gaynor1, D. Nanayakkara1, B. Abdalla2, S. Bunnapradist2, J. Schaenman1

    1Department of Internal Medicine - Division Infectious Diseases, UCLA, Los Angeles, CA, 2Department of Internal Medicine - Division Nephrology, UCLA, Los Angeles, CA

    *Purpose: To describe our clinical experience using a CMV Specific Cell Mediated Immunity (CMI) assay in solid organ transplant (SOT) recipients with late-onset CMV, defined…
  • 2019 American Transplant Congress

    Profile of Invasive Fungal Disease after Kidney Transplantation in a Single Brazilian Center

    S. C. Miranda, G. M. Pereira Junior, C. A. Felipe, A. S. Alvarenga, P. A. Macedo Souza, C. Ribeiro, S. C. Cantini

    Nephrology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

    *Purpose: This study sought to describe the epidemiology of Invasive fungal disease at a brazilian kidney transplant center.*Methods: We retrospectively evaluated the diagnoses of invasive…
  • 2019 American Transplant Congress

    Treatment of Pseudomonas Infection with Beta-Lactams Including Ceftolozane-Tazobactam in Solid Organ Transplant Recipients

    M. Henry1, J. Puvvula2, J. John Schoen1, L. Puzniak3, J. Raddatz4, T. Van Schooneveld2, S. Bergman1

    1Nebraska Medicine, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3Merck & Co., Inc, Kenilworth, NJ, 4Merck & Co., Inc, Kenilworth, NJ, NJ

    *Purpose: Ceftolozane/Tazobactam (CT) is a potent anti-pseudomonal agent with broad gram-negative activity. Our academic medical center recommends the use of CT for patients with a…
  • 2019 American Transplant Congress

    Erk-elk1-mir-711 Signalling In Cardiac Ischemia Reperfusion Injury In Heart Transplantation

    H. Zheng, Y. Su, C. Zhu, V. Veramkovich, X. Zheng

    Pathology, University of Western Ontario, London, ON, Canada

    *Purpose: This study aims to discover new molecular mechanisms involved in and to develop new treatment for preventing ischemia reperfusion injury in heart transplantation.*Methods: The…
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