ATC Abstracts

American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Human Mesenchymal Stem Cells Inhibits Hypoxia-Induced Islets Apoptosis via Regulation of Autophagy

    R. Pengfei, X. Yuzhi

    The Third Xiang Ya Hospital,Central South University, ChangSha, China

    *Purpose: Xenotransplantation of porcine islets has been an emerging and effective option for clinicians to treat type 1 diabetes recently. Comparing with other damage, hypoxic…
  • 2019 American Transplant Congress

    Clinical, Aging, Morphometric Measures & Adverse Outcomes in Kidney Transplant Recipients

    A. Muzaale1, N. Chu1, H. Ying1, B. Ross2, D. Segev1, M. McAdams-Demarco1

    1JHU, Baltimore, MD, 2UM, Ann Habor, MI

    *Purpose: Sarcopenia is a hallmark of frailty, a geriatric phenotype which is common among kidney transplant (KT) candidates and recipients. Sarcopenic-obesity is a high-risk state…
  • 2019 American Transplant Congress

    The Combination of 3-Month Estimated Glomerular Filtration Rate and Proteinuria is a Valuable Tool for Evaluating Long-Term Kidney Graft Survival

    C. Mottola1, N. Girerd2, K. Duarte3, A. Aarnink4, M. Kessler5, L. Frimat6, S. Girerd6

    1Nephrology and Kidney Transplant Unit, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 2Clinical Investigation Center 1433, INSERM U1116, INI-CRCT, F-CRIN, Lorraine University, Vandoeuvre-lès-Nancy, France, 3Clinical Investigation Center 1433, INSERM 1116, INI-CRCT, F-CRIN, Lorraine Univeristy, Vandoeuvre-lès-Nancy, France, 4Laboratoire d’Histocompatibilité, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 5Nephrology and kidney transplant unit, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France, 6Nephrology and kidney transplant unit, INI-CRCT, F-CRIN, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France

    *Purpose: Estimated glomerular filtration rate (eGFR) measured at 1 year is the usual outcome used to predict the long-term graft survival in the field of…
  • 2019 American Transplant Congress

    Absolute Quantification of Micro RNA and Messenger RNA Using a Customized Amplicon in Real Time Quantitative Polymerase Chain Reaction Assays

    C. Li, C. Snopkowski, M. Cassidy, B. Botticelli, S. Albakry, J. R. Lee, M. Lubetzky, D. Dadhania, H. Yang, R. Ding, T. Muthukumar, M. Suthanthiran

    WCMC, New York, NY

    *Purpose: Transcript abundance in biological specimens quantified by RT-PCR assay is typically expressed as fold change between groups. Absolute quantification is preferable to relative quantification…
  • 2019 American Transplant Congress

    Molecular Phenotype of Proliferative Arteriopathy in Kidney Grafts

    A. Perkowska-Ptasinska1, M. Ciszek1, D. Deborska-Materkowska1, A. Debska-Slizien2, P. F. Halloran3, M. Myslak4

    1Warsaw Medical University, Warsaw, Poland, 2Gdansk Medical University, Gdansk, Poland, 3University of Alberta, Edmonton AB, AB, Canada, 4Pomeranian Medical University, Szczecin, Poland

    *Purpose: Proliferative arteriopathy (PA) is a lesion characterized by a fibrotic tissue in the arterial intima. The phenomenon is marked by the lack of elastic…
  • 2019 American Transplant Congress

    Should Kidney Retransplants Be Performed From Either Extended Criteria Donor Or Donation After Cardio Circulatory Death Donors?

    D. Harriman, V. Gurram, A. Farney, J. Rogers, G. Orlando, C. Jay, A. Reeves-Daniel, A. Mena-Gutierrez, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta

    Wake Forest Baptist Medical Center, Winston-Salem, NC

    *Purpose: Donation after brain death expanded criteria donors (ECD) and donation after cardiocirculatory death (DCD) standard criteria donors (DCD/SCD) increase the donor organ pool but…
  • 2019 American Transplant Congress

    Reevaluating Cut-Off Points for the Expansion of Deceased Donor Criteria for Kidney Transplantation in Japan

    Y. NAKAGAWA1, M. Masahiro2, M. Tasaki2, K. Saito3, K. Takahashi4

    1Department of Urology,, Uonuma Kikan Hospital, Niigata, Japan, 2Department of Regenerative and Transplant Medicine, Niigata University, Niigata, Japan, 3Department of Urology,, Niigata University, Niigata, Japan, 4Department of Urology,, Otsukadai Clinic, Tokyo, Japan

    *Purpose: A shortage of donors poses a serious problem for organ transplantation around the world. In response, the concept of the Expanded Criteria Donor (ECD)…
  • 2019 American Transplant Congress

    The Effect Of Tacrolimus Trough Variability On Kidney Transplant Outcomes

    S. Heeney1, K. R. Szempruch1, R. Lee1, A. Mintz2, P. Serrano1, R. Detwiler1, C. Doligalski1

    1University of North Carolina Medical Center, Chapel Hill, NC, 2University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC

    *Purpose: High variability in tacrolimus as assessed by tacrolimus coefficient of variability (TCV) in trough levels of kidney transplant recipients (KTRs) has been associated with…
  • 2019 American Transplant Congress

    Belatacept Conversion for Calcineurin Inhibitor-Associated Thrombotic Microangiopathy in Kidney Transplant Recipients

    S. A. Muhsin, K. Safa, H. M. Gilligan, E. C. Heher, W. W. Williams, D. M. Wojciechowski

    Nephrology Division, MGH, Boston, MA

    *Purpose: Thrombotic Microangiopathy (TMA) in kidney transplant recipients is a serious complication that can cause graft loss. It can be associated with immunosuppressive medications such…
  • 2019 American Transplant Congress

    Chloroquine’s Effect on T cell Proliferation

    R. Muschalek1, P. Jindra2, R. Kerman2, M. Kueht2, W. Etheridge2, M. Cusick2

    1Baylor College of Medicine, Houston, TX, 2Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: An anti-malarial agent, Chloroquine (CQ), has been widely used for the treatment of rheumatoid arthritis and lupus. Although the precise mechanisms of CQ are…
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