ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    A Novel Score for Predicting Mortality and Graft Failure after Kidney Transplant

    C. Parsons, F. Shamoun, S. Patel, S. Cha, R. Heilman, M. Keddis.

    Mayo Clinic, Scottsdale.

    Purpose:To develop a novel score for predicting mortality and graft failure after kidney transplant.Methods:We reviewed a cohort of 783 kidney transplant recipients and analyzed pertinent…
  • 2018 American Transplant Congress

    Development and Validation of FLF-Transplant Score to Predict Mortality of Status 1A Candidates

    Z. Guo, B. Chen, Q. Zhao, E. Xin, Z. Zhang, L. Wang, X. He, G. Chen.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Orthotopic liver transplantation (OLT) is the definitive treatment for patients with fulminant liver failure (Status 1A). We aimed to develop a prognostic model for prediction…
  • 2018 American Transplant Congress

    Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation. A Study of the United Kingdom Transplant Registry

    P. Yiannoullou,1,2 A. Summers,1,2 C. Fullwood,2 Z. Moinuddin,1,2 I. Shapey,1,2 H. Khambalia,1,2 T. Augustine,1,2 M. Rutter,1,2 D. van Dellen.1,2

    1Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom; 2University of Manchester, Manchester, United Kingdom.

    BackgroundPatients with type 1 diabetes mellitus (T1DM) and end-stage renal disease (ESRD) suffer increased cardiovascular morbidity and mortality. Simultaneous pancreas and kidney transplantation (SPKT) improves…
  • 2018 American Transplant Congress

    Trends and Policy Influences on Multiple Listing Practices for Kidney Transplantation between 2000 and 2017

    M. Decoteau,1 D. Stewart,2 A. Toll,2 J. Case,1 C. Marsh.1

    1Organ Transplantation, Scripps Green Hospital, La Jolla, CA; 2United Network for Organ Sharing, Richmond, VA.

    BACKGROUND: Organ allocation policies continually evolve to address long transplant wait times and a limited donor organ pool. Transplant candidates may list at multiple centers…
  • 2018 American Transplant Congress

    Donor Reactive Eomesderminhi CD8+ T Cells Are Significantly Upregulated Early after Transplant in Kidney Transplant Patients without Rejection

    A. Perez-Gutierrez,1,2 D. Metes,1 S. Hariharan,1 A. Thomson,1 M. Ezzelarab.1

    1Surgery, Thomas Starzl Transplantation Institute, Pittsburgh, PA; 2Surgery, Transplantation Institute, University of Chicago, Chicago, IL.

    IntroductionMemory T cell responses play a critical role in the outcome of allo-transplantation. While the role of the T-box transcription factor Eomesodermin (Eomes) in the…
  • 2018 American Transplant Congress

    Examples of the Observer Effect in Transplantation- Unintended Consequences of Regulation and Selected Outcome Metrics

    A. Rana, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss.

    Abdominal Transplantation, Baylor College of Medicine, Houston, TX.

    Introduction: The influence of an observer on the phenomena being observed is designated as the observer effect. It is our aim to demonstrate that an…
  • 2018 American Transplant Congress

    Development of Denovo DSA after One Year Post Kidney Transplant and Clinical Outcomes in Patient on Steroid Free Immunosupression

    A. Sharfuddin, M. Yaqub, D. Mishler, W. Goggins, T. Taber, O. Adebiyi.

    Division of Renal Disease and Hypertension, Indiana University Health Transplant Program, Indianapolis, IN.

    Background: Development of Denovo donor specific antibodies (DnDSA) has been associated with poor allograft outcomes in few studies. However, there is scarcity of data evaluating…
  • 2018 American Transplant Congress

    Unique Gene Expression Signatures in Urine Distinguish BK Virus Nephropathy from Acute Rejection in Kidney Transplant Patients with Graft Dysfunction

    K. Keslar,1 P. Gotwald,1 W. Xu,2 A. Zmijewska,3 J. Chen,3 K. Newell,4 P. Heeger,5 J. Bromberg,6 R. Mannon,3 R. Fairchild,1 The CTOT Consortium.

    1Cleveland Clinic, Cleveland, OH; 2Nanostring Technologies, Seattle, WA; 3University of Alabama at Birmingham, Birmingham, AL; 4Emory University, Atlanta, GA; 5Icahn School of Medicine at Mt. Sinai, New York, NY; 6University of Maryland, Baltimore, MD.

    Acute cellular rejection and BK virus nephropathy both cause deteriorating graft function that can lead to graft loss. Distinguishing the two conditions rapidly and accurately…
  • 2018 American Transplant Congress

    Are Deceased Donor Characteristics Associated with Liver Graft Failure among Low MELD Patients Receiving a Liver Transplant Changing

    K. Atiemo,1 A. Skaro,2 R. Craig-Schapiro,1 S. Montag,1 L. VanWagner,1 M. Abecassis,1 J. Levitsky,1 L. Zhao,1 D. Ladner.1

    1Nothwestern, Chicago; 2Western University, London, Canada.

    Intr Low MELD patients have less access to liver transplantation (LT) and increasingly receive 'marginal' organs with risk of graft failure (GF). Despite increased utilization…
  • 2018 American Transplant Congress

    Ten Year Follow-Up of Islet Recipients on Anti-LFA1 Therapy: Over-Immunosuppression Leads to Operational Tolerance?

    J. Gardner,1 A. Posselt,1 S. Wisel,1 U. Mashirani,2 G. Szot,1 V. Nguyen,1 K. Johnson,1 J. McElroy,1 Q. Tang,1 P. Stock.1

    1Surgery, University of California, San Francisco, San Francisco, CA; 2Endocrinology, University of California, San Francisco, San Francisco, CA.

    Introduction: Ten-year outcomes from a cohort of five pre-uremic islet transplant (txp) recipients treated with anti-leukocyte functional antigen-1 (LFA-1) antibody Efalizumab (EFA) revealed two patients…
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