2018 American Transplant Congress
Recipient HO-1 Deficiency Decreases Post-Transplant Graft HO-1 Expression and Exacerbates Liver Transplant Damage
1Surgery, Liver Transplantation, UCLA, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.
Many preclinical studies on protective functions of heme oxygenase-1 (HO-1; hsp32) in orthotopic liver transplantation (OLT) have encouraged application of HO-1 inducing regimens in clinical…2018 American Transplant Congress
Alemtuzumab is Associated with Higher Rates of De Novo Donor Specific Antibody (DSA) in Patients with No Pre-Transplant DSA
Surgery, University of Wisconsin, Madison, WI.
Introduction: Basiliximab, alemtuzumab, and thymoglobulin are the most commonly used induction agents in the US. While many centers use depleting antibody induction therapy in patients…2018 American Transplant Congress
Modifiable Causes of Racial Disparities in Living Donor Kidney Transplant
Racial disparities between White and non-White patients in receiving living donor kidney transplants (LDKT) are large and widespread. Yet, the causes of this disparity are…2018 American Transplant Congress
Outcomes of Pregnancies in Female Liver Transplant Recipients
The purpose of this study is to describe 544 pregnancies in 278 liver transplant recipients reporting to the Transplant Pregnancy Registry International (TPR) from 1991…2018 American Transplant Congress
Enrichment of Endogenous Donor-Reactive Tregs in the Spleen and Graft during Transplantation Tolerance is the Result of Treg Proliferation and Conversion from Tconv
Surgery and Medicine, University of Chicago, Chicago, IL.
Foxp3+ regulatory T cells (Tregs) are critical mediators of immune tolerance and are absolutely required for allograft tolerance in animal models. In addition, clinical trials…2018 American Transplant Congress
Cancer Incidence after Kidney Transplantation in Saudi Arabia, Comparing Different Induction Agents
Kidney and Pancreas Transplantation, King Faisal Specialist Hospital, Riyadh, Saudi Arabia.
Cancer incidence varies among different induction agents and different population. We aim to compare the incidence of cancer post kidney transplantation among different induction agents…2018 American Transplant Congress
De Novo DSA against Third Party Extension Vessels Used in Kidney and Pancreas Transplantation
University of Wisconsin, Madison.
Third party ABO-compatible vessel allografts (VA) are sometimes used as extension vessels for kidney and pancreas transplants (TX). The frequency and implications of de novo…2018 American Transplant Congress
Early Evolution and Pathologic Characteristics of Treg-Rich Organized Lymphoid Structures (TOLS) Associated with Immunological Tolerance in Accepted Mouse Kidney Allografts
Introduction: The kidney is pro-tolerogenic by mechanisms as yet unknown. In mice, tolerance of kidney allografts can occur spontaneously in certain strain combinations, such as…2018 American Transplant Congress
Post Reperfusion Portal Flow Rate Impacts Liver Allograft and Patient Survival in Patients with Pre Transplant Portal Vein Thrombosis
Henry Ford Transplant Institute, Henry Ford Health System, Detroit, MI.
Background: Pre-transplant (pretx) portal vein thrombosis (PVT) not only makes the technical aspect of liver transplantation more challenging, it also is known to affect outcomes.…2018 American Transplant Congress
Apoptotic Exosome-Like Vesicles Induce Endothelial Cell Plasticity
Acute vascular rejection of renal allografts is associated with increased endothelial apoptosis which contributes to the development of transplant vasculopathy. We previously showed that apoptotic…
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