Am J Transplant, Volume 18, Suppl 3 Archives - Page 93 of 211 - ATC Abstracts

2018 American Transplant Congress
Metformin Use after Kidney Transplantation: A Safe Option in Carefully Selected Patients
F. Koraishy,¹ L. Vest,¹ Z. Zhang,¹ M. Schnitzler,¹ V. Dharnidharka,² D. Axelrod,³ R. Ouseph,¹ A. Naik,⁴ N. Lam,⁵ H. Randall,¹ T. Alhamad,² D. Segev,³ D. Brennan,³ B. Kasiske,⁶ G. Hess,⁷ K. Lentine.
¹Saint Louis Univ, St. Louis; ²Washington Univ, St. Louis; ³Lahey Clinic, Burlington; ⁴Univ Michigan, Ann Arbor; ⁵Univ Alberta, Edmonton; ⁶Johns Hopkins, Baltimore; ⁷Hennepin County, Minneapolis; ⁸Symphony Health, Conshohocken.
Recent guidelines support metformin as a therapeutic option in diabetic patients with mild to moderate renal insufficiency. The frequency and outcomes of metformin use in…
2018 American Transplant Congress
Development and Validation of a Socioeconomic Kidney Transplant Derailers Index (KTDI)
J. Peipert,^1,2 J. Beaumont,² M. Robbins,³ A. Paiva,³ C. Anderson,¹ A. Waterman.^1,2
¹UCLA, Los Angeles, CA; ²Terasaki Research Institute, Los Angeles, CA; ³Univ. of Rhode Island, Kingston, RI.
Transplant evaluation requires an assessment of socioeconomic challenges patients face that may derail them from obtaining a kidney transplant (KT). We developed and validated a…
2018 American Transplant Congress
High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant
X. Zhang,¹ E. Kransdorf,² J. Patel,² J. Kobashigawa.²
¹HLA and Immunogenetics Laboratory/ Comprehensive Transplant Center, Cedars-Sinai Health Systems, Los Angeles, CA; ²Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA.
Aim: Development of de novo donor specific antibodies (DSA) after heart transplant is associated with an increased risk of allograft failure. The aim of this…
2018 American Transplant Congress
T-Cell Depletion Does Not Increase the Risk of CMV Infection in Donor-Positive, Recipient-Negative Kidney Transplants Due to the Absence of Preformed CMV-Specific Cell-Mediated Immunity
M. Jarque,¹ H. Kaminski,² L. Couzi,² E. Crespo,¹ J. Déchanet-Merville,³ S. Luque,¹ N. Montero,⁴ M. Pascual,⁵ O. Manuel,^5,6 P. Merville,² O. Bestard.^1,4
¹Nephrology Lab, IDIBELL, Barcelona, Spain; ²Nephrology Dep, Hôpital Pellegrin, Bordeaux, France; ³National Center of Scientific Research, Bordeaux, France; ⁴Nephrology Dep, Bellvitge Hospital, Barcelona, Spain; ⁵Transplantation Center, Lausanne Hospital, Lausanne, Switzerland; ⁶Infectious Diseases Dep, Lausanne Hospital, Lausanne, Switzerland.
Kidney transplants (KT) with R-/D+ CMV serostatus receiving T-cell depletion induction are considered as the highest risk population for CMV infection and long-lasting prophylaxis therapy…
2018 American Transplant Congress
Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection – A Double-Blind Randomized Placebo-Controlled Trial (BORTEJECT Study)
F. Eskandary,¹ H. Regele,² G. Bond,¹ N. Kozakowski,² M. Wahrmann,¹ L. Hidalgo,³ H. Haslacher,⁴ C. Kaltenecker,¹ M-.B. Aretin,⁵ R. Oberbauer,¹ J. Reeve,⁶ P. Halloran,⁶ G. Böhmig.¹
¹Nephrology and Dialysis, Medical University Vienna, Viena, Austria; ²Institute of Clinical Pathology, Medical University Vienna, Vienna, Austria; ³Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; ⁴Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria; ⁵Pharmacy Department, General Hospital Vienna, AKH, Vienna, Austria; ⁶Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada.
Background. Antibody-mediated rejection (ABMR) is a leading cause of long-term kidney transplant loss. Optimal treatment of late ABMR is unclear, and our current knowledge is…
2018 American Transplant Congress
Trends, Patterns, and Recipient Outcomes of Kidney Transplants from Older (>60) Living Donors. A UNOS Database Analysis
A. Riaz, O. Adebiyi, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Backgroud: The selection of older donors (>60 years) has become more common. Our aim was to analyze the recent national trends of such donors and…
2018 American Transplant Congress
Comparison of BMI, Waist Circumference and Waist-to-Height Ratio for Identification of Cardiovascular Risk in Pediatric Kidney Transplant Recipients
K. Sgambat, S. Clauss, A. Moudgil.
Children's National, Washington DC.
Background: Children with kidney disease have altered body composition and short stature that may not be accurately assessed by standard methods. The measure of obesity…
2018 American Transplant Congress
Making Sense of Hepatitis B Reactivation Risk in Anti-HBc Antibody (Ab) Positive Liver Transplant Recipients
S. Leistman,¹ J. Melaragno,¹ M. Dokus,² B. Al-Judaibi,² T. Babu.³
¹Department of Pharmacy, University of Rochester Medical Center, Rochester, NY; ²Division of Transplantation, University of Rochester Medical Center, Rochester, NY; ³Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY.
Background: Limited data exists regarding the rates of reactivation of hepatitis B virus (HBV) in anti-HBc Ab positive orthotopic liver transplant (OLT) recipients. Protocols vary…
2018 American Transplant Congress
Basiliximab Induction in Simultaneous Liver-Kidney Transplant
C. Song, X. Luo, L. Pote, S. Strout, D. Segev, N. Desai, A. Gurakar, F. Navqi, J. Garonzik Wang.
The Johns Hopkins Hospital, Baltimore.
Rabbit anti-thymocyte globulin (rATG) is the most common induction agent in renal transplant recipients; however, induction agent selection for SLK recipients is not well described.…
2018 American Transplant Congress
Experience with Immunosuppressive Strategies in Vascularized Composite Allotransplantation of Face
R. Klasek,¹ B. Kollar,² S. Tasigiorgos,² B. Pomahac.²
¹Department of Pharmacy, Brigham and Women's Hospital, Boston, MA; ²Department of Surgery, Brigham and Women's Hospital, Boston, MA.
This retrospective review of the largest face transplant cohort aims to describe the evolution of immunosuppressive (IS) regimens used in face transplant recipients.All face transplants…