2018 American Transplant Congress
Hispanics' Perceptions of a Culturally Targeted Transplant Program: A Mixed Methods Study
1Northwestern University, Chicago, IL; 2Baylor University Medical Center, Dallas, TX.
Background: Although Hispanics have a disproportionally higher prevalence of end-stage renal disease than non-Hispanic whites, fewer waitlisted Hispanics receive living donor kidney transplants (LDKTs). Northwestern…2018 American Transplant Congress
A Single Center Transition of Care Model from Pediatric Heart Recipients to Adult Services Ongoing Study Model
Heart Transplant, Vanderbilt Medical Center, Nashville, TN.
This is an ongoing look at designing a pediatric to adult transition model and lessons learned over time. It has been shown that the first…2018 American Transplant Congress
Provision of Highly Specialized Aftercare by the Transplant Center Strongly Improves Patient, Pancreas and Kidney Allograft Survival in Long-Term Follow-Up after Simultaneous Pancreas-Kidney Transplantation
Despite rapid medical advancements in the field of transplantation, mean allograft survival remained at a standstill. If and to what extent a highly specialized and…2018 American Transplant Congress
Pancreas Transplant for Type 2 Diabetes is Associated with Preserved Function, but Impaired Glucose Tolerance: A Comparative Analysis
Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.
Background: The indications and outcomes of pancreas transplantation for type 2 diabetes mellitus (T2DM) remains controversial. The aim of this study was to compare the…2018 American Transplant Congress
Hypoxia Results in Endoplasmic Reticulum Stress and Activation of the Unfolded Protein Response in Isolated Human Islets and Human Donor Pancreases
Imperial College London, London, United Kingdom.
Background: The Unfolded Protein Response (UPR) is activated as an adaptive response to endoplasmic reticulum (ER) stress, however if ER stress is not resolved, UPR…2018 American Transplant Congress
Resident Perceptions and Evaluations of a Fellow-Led Transplant Service versus Resident-Led Surgical Services
Department of Surgery, University of Michigan, Ann Arbor, MI.
Background: Transplant rotations as a core requirement for surgical training have been questioned. However, surgical resident perceptions of a fellow-led transplant service have not been…2018 American Transplant Congress
Tomotherapy and Donor Hematopoietic Cells for Tolerance to Kidney Transplants in Rhesus Macaques
The goal of this project was to develop a tolerance induction protocol for MHC 1-haplotype mismatched kidney transplants (txs) in a rhesus macaque model. The…2018 American Transplant Congress
Long Noncoding RNA NEAT1 Induces Tolerogenic Dendritic Cells in Heart Transplantation
Purpose: Tolerogenic dendritic cells have been gaining interest as an efficient means of promoting antigen-specific tolerance in organ transplantation. Long noncoding RNA NEAT1 plays an…2018 American Transplant Congress
Anti-Thymocyte Globulin Directly Binds and Functionally Inhibits Allo-Regulatory Myeloid Derived Suppressor Cells
Surgery and Immunology, University of Maryland, Baltimore, MD.
BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of naturally occurring, immunosuppressive cells that may be exploitable in transplantation.There are only a few incomplete…2018 American Transplant Congress
p40 Homodimer Induced Proliferation of Endogenous Donor-Reactive Memory CD8 T Cells within High Risk Allografts Requires Memory CD8 T Cell Expression of CD122
Immunology, Cleveland Clinic, Cleveland, OH.
Increasing the duration of cold ischemic storage (CIS) from 0.5 to 8 hrs prior to transplant induces the increased proliferation of endogenous donor-reactive CD4 and…
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