ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Pre-Existing Renal Cell Carcinomas in Patients with Polycystic Kidney Disease Undergoing Simultaneous Native Nephrectomy and Living Donor Kidney Transplantation

    M. Aull,1 J. Del Pizzo,2 A. Watkins,1 S. Kapur.1

    1Surgery, Weill Cornell Medical College, New York, NY; 2Urology, Weill Cornell Medical College, New York, NY.

    Due to the structural changes to the kidney that occur in polycystic kidney disease (PKD), imaging tests may not pick up pre-transplant renal cancers in…
  • 2018 American Transplant Congress

    Long Term Outcomes of Renal Allografts with De Novo DSA in the Setting of Stable Graft Function versus Acute Rejection

    R. Knight,1 D. Nguyen,2 E. Graviss,2 T. Eagar,2 S. Kuten,3 S. Patel,3 L. Moore,1 A. Gaber.1

    1Surgery, Houston Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX; 3Pharmacy, Houston Methodist, Houston, TX.

    We sought to compare the long-term outcome of renal allograft recipients with de novo DSA (dnDSA) in the setting of stable allograft function versus dnDSA…
  • 2018 American Transplant Congress

    Central Role of Mef2 Transcription Factors in Regulation of Foxp3 Expression and Treg Function

    A. Samanta,1 L. Wang,1 R. Han,1 W. Hancock.1,2

    1CHOP, Philadelphia; 2UPenn, Philadelphia.

    Foxp3+ Tregs express 4 class IIa Hdac enzymes (Hdac4, 5, 7 & 9) with little or no catalytic activity and yet when deleted, at least…
  • 2018 American Transplant Congress

    Incisional Hernia Repair after Abdominal Solid Organ Transplant and Living Kidney Donation: A Single Institution Experience

    C. Kensinger,1 S. Phillips,2 D. Hale,2 D. Shaffer,2 B. Poulose,2 R. Baucom.3

    1University of Wisconsin, Madision; 2Vanderbilt Medical Center, Nashville; 3Baylor University Medical Center, Dallas.

    Purpose: The incidence of incisional hernias (IH) requiring operative repair in live kidney donors and abdominal transplant recipients is not well-defined. Therefore, we examined the…
  • 2018 American Transplant Congress

    Brincidofovir Was Used to Successfully Treat Adenovirus Infections in Solid Organ Transplant Recipients and Other Immunocompromised Patients

    D. Florescu,1 M. Grimley,2 G. Papanicolaou,3 V. Prasad,4 E. Vainorius,5 G. Chittick,5 T. Brundage,5 G. Nichols.5

    1Univ Nebraska Med Center, Omaha; 2Cincinnati Children's Hosp Center, Cincinnati; 3Memorial-Sloan Kettering Cancer Center, New York; 4Pediatric BMT, Duke Univ Med Center, Durham, NC; 5Chimerix, Inc., Durham.

    Background: Adenovirus (AdV) infections cause significant morbidity and mortality in immunocompromised patients. Brincidofovir (BCV) is an investigational antiviral drug with high in vitro potency against…
  • 2018 American Transplant Congress

    Identifying the Specific Causes of Kidney Allograft Loss: A Population Based Study

    C. Loheac, O. Aubert, D. VIglietti, N. Kamar, M. Delahousse, C. Lefaucheur, A. Loupy.

    Paris Translational Research Center for Organ Transplantation, Paris, France.

    Understanding the specific causes of kidney allograft loss is mandatory to improve the longevity of kidney allografts. However, the current literature is limited by the…
  • 2018 American Transplant Congress

    Mortality and ESRD in Older Live Kidney Donors with Hypertension

    F. Al Ammary,1 X. Luo,1 A. Muzaale,1 A. Massie,1 D. Brennan,1 A. Wiseman,2 J. Snyder,3 D. Segev.1

    1Johns Hopkins, Baltimore; 2University of Colorado, Aurora; 3SRTR, Minneapolis.

    Hypertension in otherwise healthy screened older kidney donor candidates is viewed as relatively benign, yet the long-term outcome of older donors with hypertension is unclear.…
  • 2018 American Transplant Congress

    Use of Surgically Placed Transversus Abdominis Plane (TAP) Block Catheter with Local Anesthetic Infusion in Renal Transplantation

    M. Dib,1 S. Borden,2 T. Schell,1 P. Stahler,1 T. Al-Qaoud,1 E. Martinez,1 E. Grodstein,1 A. D'Alessandro,1 J. Odorico,1 L. Fernandez,1 J. Mezrich,1 R. Redfield,1 D. Foley,1 D. Al-Adra,1 D. Kaufman.1

    1Surgery, University of Wisconsin-Madison, Madison, WI; 2Anesthesia, University of Wisconsin-Madison, Madison, WI.

    BackgroundRenal transplant recipients have limitations in pain management, given the nephrotoxicity of NSAIDS and contraindications to regional neuroaxial techniques. Although opioids are widely used post-transplant,…
  • 2018 American Transplant Congress

    T Cell Exhaustion Contributes to Operational Tolerance of Liver Allografts in Pediatric Liver Transplant Recipients

    B. Ramaswami,1 M. Marrari,2 O. Yoshida,5 X. Guo,3 W. Hoffman,3 C. Bentlejewski,2 D. Metes,1 A. Demetris,1,2 A. Zeevi,2 A. Thomson,1 G. Mazariegos,4 G. Chalasani.1,3

    1Surgery, Starzl Transplantation Institute, Pittsburgh, PA; 2Pathology, University of Pittsburgh, Pittsburgh, PA; 3Medicine, University of Pittsburgh, Pittsburgh, PA; 4Children's Hospital, University of Pittsburgh, Pittsburgh, PA; 5Gastroenterology, Ehime University Graduate School of Medicine, Toon-shi, Ehime-ken, Japan.

    Operational tolerance in the absence of immunosuppression can be successfully attained in pediatric liver transplant recipients. Although DSA are observed in a proportion of operationally…
  • 2018 American Transplant Congress

    Medication Adherence: Does Where You Live Matter?

    S. Wadhwani,1 S. Taylor,1 C. Brokamp,1 W. Guo,1 E. Shemesh,2 J. Bucuvalas.1

    1Cincinnati Children's Hospital Medical Center, Cincinnati; 2Mount Sinai School of Medicine, New York.

    Background & Objectives: Medication non-adherence remains problematic in pediatric liver transplant (LT)[mdash]estimates suggest that up to 53% of adolescents are non-adherent. We leveraged data from…
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