Am J Transplant, Volume 18, Suppl 3 Archives - Page 79 of 211 - ATC Abstracts

2018 American Transplant Congress
Psychosocial Factors Affecting Recipients of Vascular Composite Allotransplantation
S. Rasmussen, M. Henderson, C. Cooney, J. Shores, W. Lee, D. Segev, G. Brandacher.
JHU, Baltimore.
Background: While vascularized composite allotransplantation (VCA) is an increasingly successful therapy, medication non-adherence appears to be an important cause of graft loss. Psychosocial factors predict…
2018 American Transplant Congress
Parathyroid Cell Xenotransplantation with Ultrapure Alginate Based Microencapsulation Technique
B. Goncu,¹ E. Yucesan,² H. Basoglu,³ M. Celikten,¹ O. Huseyinbas,¹ B. Ozdemir,¹ N. Ozten Kandas,⁴ F. Akbas,⁵ Y. Ersoy,⁶ E. Aysan.⁶
¹Bezmialem Vakif University, Experimental Research Center, Istanbul, Turkey; ²Bezmialem Vakif University, Institute of Life Sciences and Biotechnology, Istanbul, Turkey; ³Bezmialem Vakif University, Faculty of Medicine, Department of Biophysics, Istanbul, Turkey; ⁴Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey; ⁵Bezmialem Vakif University, Faculty of Medicine, Department of Medical Biology, Istanbul, Turkey; ⁶Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey.
Permanent hypoparathyroidism (PH) is a serious clinical condition and unique treatment option is parathyroid allotransplantation (PA). The most important obstacle for PA is an immune…
2018 American Transplant Congress
NKG2C+CD57+ NK (G2C+57+) Cells Expanded by CMV Infection Are Highly Responsive to Allo-Antibody (Ab)-Mediated NK Cell Stimulation
B. Shin,¹ D. Puliyanda,² H. Pizzo,² S. Jordan,² M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: Active CMV infection is known to be associated with risk for ABMR in allograft recipients. Ab-dependent cellular cytotoxicity (ADCC) primarily mediated by NK cells…
2018 American Transplant Congress
Genetic Risk Factors of Post-Transplant Thrombocytopenia in Kidney Allograft Recipients
D. Min,¹ Y. Chang,² T. Shah.³
¹College of Pharmacy, Western University of Health Sciences, Pomoma, CA; ²National Institute of Transplantation Foundation, Los Angeles, CA; ³Multiorgan Transplantation Center, St. Vincent Medical Center, Los Angeles, CA.
Background: Posttransplant thrombocytopenia is prevalent after renal transplantation, which is associated with increased risk of bleeding and other complications. The CXC motif chemokine 12 (CXCL12)…
2018 American Transplant Congress
Kidney Transplantation (KTx) Using Kidneys from Deceased Donors (DD) with Severe AKI Does Not Negatively Impact 1 Year Biopsy Chronic Changes
A. Kumar, A. Srinivasan, A. Mathur, J. Huskey, H. Khamash, M. Smith, A. Moss, K. Reddy, R. Heilman.
Mayo Clinic, Phoenix.
BackgroundDespite the persistent donor shortage, donor kidneys with an acute kidney injury are declined. The aim of this study to determine the difference in biopsy…
2018 American Transplant Congress
Late Conversion from Calcineurin Inhibitors to Belatacept is Associated with a Sustained Improvement in Kidney Allograft Function
S. Sethi, J. Choi, A. Vo, R. Najjar, A. Peng, S. Jordan, E. Huang.
Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.
Introduction: Belatacept was shown to have longer kidney graft survival and higher eGFR at 7 years than a calcineurin inhibitor (CNI)-based regimen in the BENEFIT…
2018 American Transplant Congress
Long-Term Effects of Ketoconazole in Rapid Tacrolimus Metabolizers Post-Renal Transplantation
J. Ching,¹ S. Anders,¹ M. Janusek,¹ L. Hutchinson,¹ A. Freeman,¹ U. Patel,¹ A. Mohammed,⁴ H. Bohorquez.^2,3
¹Department of Pharmacy, Ochsner Clinical Foundation, New Orleans, LA; ²Multi-Organ Transplant Institute, Ochsner Clinical Foundation, New Orleans, LA; ³The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA; ⁴Academic Center, Ochsner Clinical Foundation, New Orleans, LA.
Introduction: Genetic polymorphisms in cytochrome P-450 enzymes can cause variations in tacrolimus (tac) metabolism. Ketoconazole (keto), a potent CYP450 and P-glycoprotein inhibitor, can be used…
2018 American Transplant Congress
Clinical Significance of Tacrolimus Trough Level at the Early Period after Kidney Transplantation
W. Park,^1,2 S. Yeo,¹ S. Kang,^1,2 H. Park,¹ K. Jin,^1,2 S. Park,^1,2 S. Han.^1,2
¹Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea; ²Keimyung University Kidney Institute, Daegu, Republic of Korea.
Background:The stable immunosuppressant level at the early period after kidney transplantation (KT) is one of the most important factors to decide the prognosis of KT.…
2018 American Transplant Congress
Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study
Y. Kim,¹ Y. Chiang,² S. Kim,³ M. Kim,⁴ S. Park,⁵ S. Wu,⁶ K. Horita,⁷ Y. Nakashima,⁷ H. Jiang,⁸ D. Han.¹
¹Asan Medical Center, Seoul, Korea; ²Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; ³Samsung Medical Center, Seoul, Korea; ⁴Severance Hospital, Seoul, Korea; ⁵Dongsan Medical Center, Daegu, Korea; ⁶Tri-Service General Hospital, Taipei City, Taiwan; ⁷Astellas Pharma, Inc., Tokyo, Japan; ⁸Astellas Pharma, Inc., Maao, Singapore.
A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
2018 American Transplant Congress
Making Right Donor Nephrectomy Great Again: Evaluating Right Hand Assisted Retroperitoneal Donor Nephrectomy
H. Alahdal,¹ F. Alghamdi,¹ M. Shoukri,² J. Brockmann,¹ D. Broering.¹
¹Kidney and Pancreas Transplantation, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; ²Cell Biology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Background: Living kidney transplant offers ideal therapy of end stage renal disease patients. A variety of minimal invasive techniques for donor nephrectomy have been described…