ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    End Stage Kidney Disease Risk Profile in Living Kidney Donors for Pediatric versus Adult Kidney Transplant Recipients in Australia and New Zealand

    D. Lee,1,2 J. Whitlam,2 N. Cook,2 A. Walker,3 F. Ierino,4 M. Roberts,1 J. Kausman.3

    1Department of Renal Medicine, Eastern Health, Melbourne, VIC, Australia; 2Department of Nephrology, Austin Health, Melbourne, VIC, Australia; 3Department of Nephrology, Royal Children's Hospital, Melbourne, VIC, Australia; 4Department of Nephrology, St Vincent's Hospital, Melbourne, VIC, Australia.

    Background: Living kidney donors (LKD) for pediatric kidney transplant recipients (KTR) have a high motivation to donate due to the clear benefits to the KTR…
  • 2018 American Transplant Congress

    Multivariate Cox Proportional Hazards Model for Estimating Long-Term Risk of Aging Kidney Transplant Recipients

    A. Yaldo, I. Bajjoka, X. Han, C. Crombez, M. Abouljoud.

    Henry Ford Transplant Institute, Detroit, MI.

    Purpose: The growing number of elderly kidney transplant recipients (KTR) presents an opportunity to analyze and predict long-term outcomes and risk in this aging population.Methods:…
  • 2018 American Transplant Congress

    Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?

    D. Kollmann,1 S. Neong,1 R. Rosales,1 G. Sapisochin,1 M. Bhat,1 M. Cattral,1 P. Greig,1 L. Lilly,1 D. McGilvray,1 A. Ghanekar,1 D. Grant,1 M. Selzner,1 F. Wong,2 N. Selzner.1

    1Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; 2Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.

    Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…
  • 2018 American Transplant Congress

    Living Liver Donation: The Role of Facebook in Directed Donation

    A. Lai, J. Steel, S. Ganesh, O. Ola, S. Shen, N. Zharichenko, S. Nawaz, A. Tevar, A. Humar.

    Surgery, University of Pittsburgh, Pittsburgh, PA.

    Background: The aims of this study were to understand the number and type of directed living liver donors who contacted the transplant team after learning…
  • 2018 American Transplant Congress

    Renal and Bone Safety in Post Liver Transplant Patients with Chronic Kidney Disease Receiving Tenofovir Alafenamide for HBV Prophylaxis

    E. Gane,1 B. George,1 S. Munn,1 H. Wang,2 V. Suri,2 A. Gaggar.2

    1Auckland City Hospital, Auckland, New Zealand; 2Gilead Sciences, Foster City, CA.

    Background and Aims: Chronic Hepatitis B (CHB) remains a leading indication for orthotopic liver transplantation (OLT) globally. Common complications following OLT include renal dysfunction secondary…
  • 2018 American Transplant Congress

    Incisional Hernia after Orthotropic Liver Transplantation: A Systematic Review and Meta-Analysis

    J. Butler, D. O'Brien, J. Kays, C. Kubal, B. Ekser, J. Fridell, R. Mangus, J. Powelson.

    Transplant Surgery, Indiana University, Indianapolis, IN.

    Background: Incisional hernia is a well-known complication of orthotopic liver transplantation. Despite wide recognition of the impact of this problem, the incidence remains imprecisely known.Methods…
  • 2018 American Transplant Congress

    Variation in Hypothermic Machine Perfusion Utilization and Clinical Outcomes for Deceased-Donor Kidneys

    V. Krishnamoorthy,1 S. Wunsch,2 K. O'Connor,2 M. Souter.3

    1Anesthesiology, Duke University, Durham, NC; 2LifeCenter Northwest, Bellevue, WA; 3Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.

    Introduction:Hypothermic machine perfusion (HMP) has been shown to be an effective method for preserving kidney allografts from deceased donors (1), but data suggests that low-risk…
  • 2018 American Transplant Congress

    Living-Donor Preemptive Kidney Transplant Timing Calculator: An Online Decision Support Tool

    M. Barah,1 M. Kurt,2 A. Khojandi,1 B. Tanriover.3

    1Industrial and Systems Engineering, Univeristy of Tennessee, Knoxville, TN; 2Economic and Data Sciences, Merck Research Labs, North Wales, PA; 3Division of Nephrology, UT Southwestern Medical Center, Dallas, TX.

    Purpose: Optimal glomerular filtration rate (GFR) and timing for living preemptive kidney transplantation (PKT) is not well studied.Method: We developed an online engine to calculate…
  • 2018 American Transplant Congress

    Glycolytic Bias in mTORC2-Deficient Dendritic Cells Potentiates Antigen-Specific Immunity and Accelerates Graft Rejection

    A. Watson,1 H. Dai,1 J. Diaz-Perez,2 A. Menk,3 M. Killeen,2 G. Delgoffe,3 A. Mathers,2 A. Thomson.1

    1Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; 2Dermatology, University of Pittsburgh, Pittsburgh, PA; 3Cancer Institute, University of Pittsburgh, Pittsburgh, PA.

    The mechanistic target of rapamycin (mTOR) is known to function in two complexes: mTOR complex 1 (mTORC1) and mTORC2. While the function of mTORC1 in…
  • 2018 American Transplant Congress

    mRNA Transcript Profiles of 14 Genes in Plasma Exosome Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts

    H. Zhang,1 E. Huang,2 C. Nast,3 J. Kahwaji,2 A. Vo,2 S. Jordan,2 M. Toyoda.1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 3Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Previously we reported that mRNA transcript profiles of 4 genes (gp130, SH2D1B, TNFα and CCL4) in plasma exosome could predict the risk of ABMR,…
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