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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    High Prevalence of Hypertension and Alterations in Rhythmicity in Recipients of Pediatric Transplants

    N. Memaran,1 M. Kirchner,2 R. Blöte,1 B. Maecker-Kolhoff,3 I. Goldschmidt,1 C. Müller,4 J. Epping,5 R. Sugianto,1 B. Borchert,1 B. Schmidt,6 E. Wühl,7 A. Melk.1

    1Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Med. School, Hanover, Germany; 2Department of Medical Biometry, University of Heidelberg, Heidelberg, Germany; 3Department of Pediatric Hematology and Oncology, Hannover Med. School, Hanover, Germany; 4Department of Pediatric Pulmonology, Allergology, and Neonatology, Hannover Med. School, Hanover, Germany; 5Department of Medical Sociology, Hannover Med. School, Hanover, Germany; 6Department of Nephrology and Hypertension, Hannover Med. School, Hanover, Germany; 7Division of Pediatric Nephrology, University Children's Hospital, Heidelberg, Germany.

    Hypertension (HTN) is a major issue after transplantation (Tx). Ambulatory blood pressure (BP) monitoring (ABPM) permits the diagnosis of masked HTN and nocturnal HTN. Fourier…
  • 2018 American Transplant Congress

    Cost Analysis of Biliary Strictures Following Orthotopic Liver Transplantation in the United States

    J. Jones,1 N. Bhutiani,1 D. Wei,2 L. Goldstein,3 R. Martin,1 C. Jones,1 R. Cannon.1

    1Surgery, University of Louisville, Louisville, KY; 2Real-world Data Analytics and Research, Johnson & Johnson, New Brunswick, NJ; 3Health Economics and Market Access, Ethicon, Inc., Somerville, NJ.

    Introduction: While previous studies have evaluated risk factors, management, and outcomes in patients who develop biliary strictures (BS) after undergoing orthotopic liver transplantation (OLT), none…
  • 2018 American Transplant Congress

    Providing Transplant Candidates with Patient-Specific Public Reports about Programs That Transplant Patients Like Them

    C. Schaffhausen,1,4 M. Bruin,3 S. Chu,3 A. Matas,5 J. Lake,6 W. Kim,7,4 S. Biggins,8 J. Snyder,2,4 B. Kasiske,1,4 A. Israni.1,2

    1Department of Medicine, Hennepin County Medical Center (HCMC), University of Minnesota (UMN), Minneapolis, MN; 2Department of Epidemiology and Community Health, UMN, Minneapolis, MN; 3College of Design, UMN, Minneapolis, MN; 4Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; 5Department of Surgery, UMN, Minneapolis, MN; 6Division of Gastroenterology, Hepatology, and Nutrition, UMN, Minneapolis, MN; 7Division of Gastroenterology and Hepatology, Stanford University, Palo Alto, CA; 8Division of Hepatology, University of Washington, Seattle, WA.

    The Scientific Registry of Transplant Recipients (SRTR) provides federally mandated program-specific reports (PSR) to the public. Previous patient feedback indicated interest in tailoring search information…
  • 2018 American Transplant Congress

    The Effect of Pre-Transplant Insomnia and Post-Transplant Insomnia on Survival among Solid Organ Recipients

    K-.F. Lee,2 Y. Tsai,1 C. Lin,1 C-.B. Hsieh,3,5 S. Wu,4 T. Chen,5 Y-.C. Lin,1 W-.H. Lee,6,7 F. Lin,8 C. Tsai.1,9,10

    1Cardiovascular Surgery, Tri-Service General Hospital, Taipei, Taiwan; 2Biobank Management Center, Tri-Service General Hospital, Taipei, Taiwan; 3General Surgery, Hualien Armed Forces General Hospital, Hualien County, Taiwan; 4Urology, Tri-Service General Hospital, Taipei, Taiwan; 5General Surgery, Tri-Service General Hospital, Taipei, Taiwan; 6Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 7Pathology, Taipei Medical University-Shuang Ho Hospital, New Taipei, Taiwan; 8Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 9Cardiovascular Surgery, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan; 10Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, Taiwan.

    BackgroundBecause studies about insomnia among organ recipients were scarce, we used National Health Insurance Research Database (NHIRD) between 2001 and 2012 to understand how pre-transplant…
  • 2018 American Transplant Congress

    Pretransplant Use of Rituximab is Associated with Posttransplant Malignancies Events and Death by Neoplasia in Incompatibility Living Donor Kidney Transplants

    I. Revuelta,1,2,3,4 V. Tubita,2 D. Cucchiari,1,2 E. De Sousa,1 P. Piselli,5 M. Lozano,6 J. Cid,6 E. Palou,7 J. Martorell,7 F. Oppenheimer,1,2,3,4 F. Diekmann,1,2,3,4 J. Campistol.1,2,3,4

    1Renal Transplant Unit. Department of Nephrology and Kidney Transplant. Hospital Clinic, Barcelona, Spain; 2Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; 3REDINREN, Madrid, Spain; 4Barcelona University, Barcelona, Spain; 5Dipartamento di Epidemiologia e Ricerca Pre-Clinica. IRCCC, Roma, Italy; 6Department of Apheresis. Hospital Clinic, Barcelona, Spain; 7Department of Immunology. Hospital Clinic, Barcelona, Spain.

    Introduction: Incompatibilities is a challenge in kidney transplantation. Potent immunosuppression approach based on desensitization protocols (DS) are usually needed; However, controversies in results and lack…
  • 2018 American Transplant Congress

    Rapamycin Therapy Impairs Treg Expression of CXCR3 and Limits Treg-Dependent Survival of Vascularized Composite Allotransplants

    H. Xu,1 Z. Chen,2 W. Hancock,3,4 S. Levin,5 Y. Zhang.1

    1Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Medicine School of Shanghai Jiaotong University, Shanghai, China; 2Institute of Immunology, University of Pennsylvania, Philadelphia; 3Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia; 4Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia; 5Orthopaedic Surgery and Plastic Surgery, Hospital of the University of Pennsylvania, Philadelphia.

    Vascularized Composite Allotransplantation (VCA) is a procedure to restore limb function or facial appearance. Rapamycin is used in efforts to preserve host Treg function and…
  • 2018 American Transplant Congress

    Influence of Dendritic Cell Subsets on Enhancing Oral Tolerance in Cardiac Transplantation Model

    G. Gu, T. Lu, N. Xu, Q. Xia.

    Department of Liver Surgery, Renji Hospital, Affiliated by Shanghai Jiaotong University Medical School, Shanghai, China.

    Oral tolerance has been implicated in the protection of transplant rejection in the animal models. Antigen presenting cells (APCs) are responsible for sampling their environment…
  • 2018 American Transplant Congress

    Pre-Transplant versus De Novo Donor Specific Antibodies: Differences in Clinical Outcomes and Antibody Mediated Rejection

    M. Ajaimy, N. Hayde, A. Colovai, E. Akalin.

    Montefiore-Einstein Transplant Center, Montefiore-Einstein Transplant Center, Bronx.

    Background: Antibody mediated rejection (ABMR) can occur through pre-transplant(tx) vs. de novo donor specific antibodies (DSA). Clinical outcomes, allograft injury and dynamics of DSAs have…
  • 2018 American Transplant Congress

    Timing of Treatment for Chronic Hepatitis C Infection in Patients with End-Stage Renal Disease Awaiting Transplantation

    M. Eckman,1 E. Woodle,2 C. Thakar,1 F. Paterno,2 K. Sherman.1

    1Medicine, University of Cincinnati, Cincinnati, OH; 2Surgery, University of Cincinnati, Cincinnati, OH.

    BackgroundIt is unclear whether patients with chronic hepatitis C virus (HCV) infection and end-stage renal disease (ESRD) should be treated for HCV before transplant or…
  • 2018 American Transplant Congress

    Time-Effect of Donor and Recipient Characteristics on Graft Survival after Kidney Transplantation

    E. Molmenti,1 J. Yang,3 C. Molmenti,2 E. Grodstein,1 H. Rilo,1 L. Teperman.1

    1Surgery, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; 2Feinstein Institute, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; 3Epidemiology, Mailman Schoool of Public Health, Columbia University, New York, NY.

    BackgroundThe current kidney allocation system (KAS) is based on the Kidney Donor Profile Index (KDPI) and the Estimated Post-Transplant Survival (EPTS), quality-based “longevity matching” strategies…
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