2018 American Transplant Congress
Challenges in Cultural and Linguistic Discordance in Caring for Somali Kidney Transplant Recipients at a Large-Volume Transplant Center
OBJECTIVE: Kidney Transplantation (KT) demands navigation of a complex healthcare system and adherence to lifelong immunosuppression therapy. Cultural and linguistic discordance between patients and providers…2018 American Transplant Congress
Decline in Pancreas Transplantation Numbers is Accompanied with Lower Publication Rates
Introduction: After several years of growth in many pancreas transplant (PTx) programs, the United Network for Organ Sharing (UNOS) reports a decline in PTx numbers…2018 American Transplant Congress
Pancreas and Kidney Co-Transplantation in Type II Diabetes: A Single Center Experience
Background: Diabetic CKD patients present increased morbidity and mortality due to cardiovascular complications. Pancreas transplantation can restore insulin independence in patients with type I diabetes…2018 American Transplant Congress
Trends in Safety Reporting to UNOS by Event Type
The UNOS Operations and Safety Committee is charged with reviewing reported patient safety situations, identifying safety gaps, addressing high frequency and high impact events, and…2018 American Transplant Congress
Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control
1Quality Assurance, LABS, Inc., Centennial, CO; 2Infectious Disease, LABS, Inc., Philadelphia, PA.
Background: Our STAT donor-screening lab implemented a new LIMS that is used to manage patient orders, testing and reporting. We intentionally customized the LIMS to…2018 American Transplant Congress
The Regulatory Role of Plasma Cells (as Bregs) is Counterbalanced by a NOVEL Inflammatory Role in Murine Transplant and Autoimmune Models
Plasma Cells (PCs; B220lowCD138hiBlimp1+Ig+) in LN and spleen were shown to be the major source of B cell lineage IL-10, and absence of PCs worsens…2018 American Transplant Congress
CD4+CD25bright Regulatory T Cells Prevent Acute Xenogeneic GVHD
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
Graft-versus-host disease (GVHD) is a major complication and limitation to the broad application of hematopoietic stem cell transplantation. Cell therapy has emerged as a promising…2018 American Transplant Congress
Galangin Promotes Treg Development and Function
Introduction: FoxP3+ Treg cells are central in controlling immune responses and transplant tolerance. CD73 (ecto-5'-nucleotidase), which serves to convert AMP to adenosine, is essential for…2018 American Transplant Congress
Comparative Analysis of Alloantigen-Stimulated Gene Expression in HIV(+) Liver Transplant Rejectors versus Non-Rejectors
Surgery, University of California, San Francisco, San Francisco, CA.
In a multi-center, prospective trial of solid-organ transplantation in persons with HIV, recipients had a 2-3x increased rejection rate when compared to historical data on…2018 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) with Human Hemoglobin(Hb)-Based Oxygen Carriers (HBOCs)perfusate Decreased Hepatocellular Reperfusion Injury of Donation after Cardiac Death (DCD) Donor in Pig Model
Subnormothermic machine perfusion (SNMP) alleviate hepatoceller injury during organ preservation. However more oxygen is required when perfusate SNMP. Some studies demonstrated that SNMP with hemoglobin-based…
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