ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Challenges in Cultural and Linguistic Discordance in Caring for Somali Kidney Transplant Recipients at a Large-Volume Transplant Center

    K. Peterson,1 O. Serrano,1 M. Odegard,1 S. Mongin,2 D. Berglund,3 D. Vock,4 S. Chinnakotla,1 T. Dunn,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas.1

    1Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN; 2Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN; 3Informatics Services for Research and Reporting, Fairview Health Services, Minneapolis, MN; 4Division of Biostatistics, University of Minnesota, Minneapolis, MN.

    OBJECTIVE: Kidney Transplantation (KT) demands navigation of a complex healthcare system and adherence to lifelong immunosuppression therapy. Cultural and linguistic discordance between patients and providers…
  • 2018 American Transplant Congress

    Decline in Pancreas Transplantation Numbers is Accompanied with Lower Publication Rates

    S. Benjamens,1 C. Margreiter,2 E. de Koning,3 H. Leuvenink,1 R. Pol.1

    1University Medical Center Groningen, Groningen, Netherlands; 2Medical University Innsbruck, Innsbruck, Austria; 3Leiden University Medical Center, Leiden, Netherlands.

    Introduction: After several years of growth in many pancreas transplant (PTx) programs, the United Network for Organ Sharing (UNOS) reports a decline in PTx numbers…
  • 2018 American Transplant Congress

    Pancreas and Kidney Co-Transplantation in Type II Diabetes: A Single Center Experience

    J. Choi, J. Jung, H. Kwon, S. Shin, Y. Kim, D. Han.

    Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University Ulsan College of Medicine, Seoul, Korea.

    Background: Diabetic CKD patients present increased morbidity and mortality due to cardiovascular complications. Pancreas transplantation can restore insulin independence in patients with type I diabetes…
  • 2018 American Transplant Congress

    Trends in Safety Reporting to UNOS by Event Type

    A. Doyle,1 S. Tlusty,2 R. Urban,2 M. Marvin,3 E. Hollinger,5 D. Marshman,4 M. Green.5

    1Medicine, University of Virginia, Charlottesville, VA; 2UNOS, Ichmond, VA; 3Surgery, Geisinger, Davville, PA; 4LifeLink Foundation, Norcross, GA; 5Surgery, University of Pittsbugh, Pittsburgh, PA; 6Surgery, Rush Medical Center, Chicago, IL.

    The UNOS Operations and Safety Committee is charged with reviewing reported patient safety situations, identifying safety gaps, addressing high frequency and high impact events, and…
  • 2018 American Transplant Congress

    Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control

    S. Dionne,2 K. Klama,2 H. Rashid,2 A. Niedzinski.2

    1Quality Assurance, LABS, Inc., Centennial, CO; 2Infectious Disease, LABS, Inc., Philadelphia, PA.

    Background: Our STAT donor-screening lab implemented a new LIMS that is used to manage patient orders, testing and reporting. We intentionally customized the LIMS to…
  • 2018 American Transplant Congress

    The Regulatory Role of Plasma Cells (as Bregs) is Counterbalanced by a NOVEL Inflammatory Role in Murine Transplant and Autoimmune Models

    Z. Song,1,2 Y. Zhou,2 Q. Ding,1 D. Rothstein.1

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh; 2School of Medicine, Tsinghua University, Beijing, China.

    Plasma Cells (PCs; B220lowCD138hiBlimp1+Ig+) in LN and spleen were shown to be the major source of B cell lineage IL-10, and absence of PCs worsens…
  • 2018 American Transplant Congress

    CD4+CD25bright Regulatory T Cells Prevent Acute Xenogeneic GVHD

    Y. Huang, A. Merchak, H. Xu, A. Chhabra, A. Khalil, Y. Wen, M. Binion, M. Badder, L. Kahn, S. Ildstad.

    Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.

    Graft-versus-host disease (GVHD) is a major complication and limitation to the broad application of hematopoietic stem cell transplantation. Cell therapy has emerged as a promising…
  • 2018 American Transplant Congress

    Galangin Promotes Treg Development and Function

    F. Liang,1 H. Fang,1 R. Zhang,1 Q. Chen,2 J. Ochando,3 Y. Ding,1 J. Xu.1

    1Department of Immunology, Capital Medical University, Beijing, China; 2Department of Thoracic Surgery, Chaoyang Hospital, Beijing, China; 3Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

    Introduction: FoxP3+ Treg cells are central in controlling immune responses and transplant tolerance. CD73 (ecto-5'-nucleotidase), which serves to convert AMP to adenosine, is essential for…
  • 2018 American Transplant Congress

    Comparative Analysis of Alloantigen-Stimulated Gene Expression in HIV(+) Liver Transplant Rejectors versus Non-Rejectors

    S. Chu, K. Lee, C. Ward, P. Stock, Q. Tang.

    Surgery, University of California, San Francisco, San Francisco, CA.

    In a multi-center, prospective trial of solid-organ transplantation in persons with HIV, recipients had a 2-3x increased rejection rate when compared to historical data on…
  • 2018 American Transplant Congress

    Subnormothermic Machine Perfusion (SNMP) with Human Hemoglobin(Hb)-Based Oxygen Carriers (HBOCs)perfusate Decreased Hepatocellular Reperfusion Injury of Donation after Cardiac Death (DCD) Donor in Pig Model

    T. Shonaka,1 N. Matsuno,1 H. Obara,2 R. Yoshikawa,2 Y. Nishikawa,3 M. Gochi,1 M. Otani,1 H. Takahashi,1 H. Azuma,3 H. Sakai,4 H. Furukawa.1

    1Department of Surgery, Asahikawa Medical University, Asahikawa, Japan; 2Tokyo Metroporitan University, Tokyo, Japan; 3Asahikawa Medical University, Asahikawa, Japan; 4Nara Medical University, Nara, Japan.

    Subnormothermic machine perfusion (SNMP) alleviate hepatoceller injury during organ preservation. However more oxygen is required when perfusate SNMP. Some studies demonstrated that SNMP with hemoglobin-based…
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