ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Comparative Analysis of Alloantigen-Stimulated Gene Expression in HIV(+) Liver Transplant Rejectors versus Non-Rejectors

    S. Chu, K. Lee, C. Ward, P. Stock, Q. Tang.

    Surgery, University of California, San Francisco, San Francisco, CA.

    In a multi-center, prospective trial of solid-organ transplantation in persons with HIV, recipients had a 2-3x increased rejection rate when compared to historical data on…
  • 2018 American Transplant Congress

    Subnormothermic Machine Perfusion (SNMP) with Human Hemoglobin(Hb)-Based Oxygen Carriers (HBOCs)perfusate Decreased Hepatocellular Reperfusion Injury of Donation after Cardiac Death (DCD) Donor in Pig Model

    T. Shonaka,1 N. Matsuno,1 H. Obara,2 R. Yoshikawa,2 Y. Nishikawa,3 M. Gochi,1 M. Otani,1 H. Takahashi,1 H. Azuma,3 H. Sakai,4 H. Furukawa.1

    1Department of Surgery, Asahikawa Medical University, Asahikawa, Japan; 2Tokyo Metroporitan University, Tokyo, Japan; 3Asahikawa Medical University, Asahikawa, Japan; 4Nara Medical University, Nara, Japan.

    Subnormothermic machine perfusion (SNMP) alleviate hepatoceller injury during organ preservation. However more oxygen is required when perfusate SNMP. Some studies demonstrated that SNMP with hemoglobin-based…
  • 2018 American Transplant Congress

    Long-Term Success of Treatment for Cardiac Transplant AMR May Depend Upon Suppressing Class II Donor Specific Antibodies

    J. Hofmann,1 D. Weisshaar,2 D. Kiprov.3

    1Dept of Medicine, California Pacific Medical Center, San Francisco, CA; 2Dept of Medicine, Kaiser Permanente, Santa Clara, CA.

    Antibody mediated rejection (AMR) in cardiac transplant (tspt) patients (pts) is primarily mediated by donor specific antibodies (DSAs) and associated with reduced long-term graft survival.…
  • 2018 American Transplant Congress

    Is Renal Function after Heart Transplantation an Issue for Patients with Cardiac Amyloidosis?

    J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Cardiac amyloidosis (CA) (AL and ATTR) is an expanding indication for transplantation. Post-transplant renal function may be affected numerous factors including pre-transplant cardiorenal syndrome,…
  • 2018 American Transplant Congress

    The Renal Sparing Protocol after Heart Transplant That Keeps Giving

    M. Kittleson, J. Patel, E. Kransdorf, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, R. Sharoff, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Calcineurin inhibitors (CNI) such as cyclosporine and tacrolimus are known to cause chronic renal failure. As a result, programs have developed renal-sparing protocols (RSP)…
  • 2018 American Transplant Congress

    Kidney after Liver Transplant: A Matched Pair Analysis

    M. Eerhart, J. Reyes, J. Danobeitia, L. Zitur, P. Chlebeck, L. Fernandez.

    Surgery, University of Wisconsin, Madison, WI.

    Background: Kidney after liver (KAL) transplantation is the best therapeutic option for patients with ESRD after liver transplantation (OLT). Current allocation policies create a safety…
  • 2018 American Transplant Congress

    Many Highly Sensitized Candidates Still Waiting for Transplant Despite the Kidney Allocation System Change: Making the Case for Incompatible Transplantation

    C. Schinstock, B. Smith, A. Bentall, M. Stegall.

    Von Liebig Center for Transplantation and Clinical Regenerative Medicine, Mayo Clinic, Rochester, MN.

    Introduction: The rate of kidney transplantation in highly sensitized individuals has increased since the kidney allocation system (KAS) change, but it remains unclear who has…
  • 2018 American Transplant Congress

    ABO Incompatible Deceased Donor Kidney Transplantation – Time to Remove the Barrier

    J. Melancon,1 M. Nayebpour,2 K. Mahendran,1 H. Spivak,1 N. Koizumi.2

    1Transplant Institute and Division of Transplant Surgery, The George Washington University Hospital, Washington, DC; 2George Mason University, Washington, DC.

    Objective: To propose a new allocation system for deceased donor kidney transplants that would decrease cold ischemia time, increase HLA matching, decrease kidney discard rates…
  • 2018 American Transplant Congress

    Safety and Efficacy of Real-World Use of Everolimus for Kidney Transplant Patients: Post-Marketing Surveillance in Japan

    H. Harada,1 Y. Watarai,2 J. Uchida,3 O. Kamisawa.4

    1Sapporo City General Hospital, Sapporo, Japan; 2Nagoya Daini Red Cross Hospital, Nagaya, Japan; 3Osaka City University, Osaka, Japan; 4Novartis Pharma K.K., Tokyo, Japan.

    Background and purpose: After the approval of everolimus (EVR) in 2011 in Japan to prevent organ rejection in kidney transplant (KTx) patients, no data on…
  • 2018 American Transplant Congress

    The Impact of Marginal Factors on Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation

    T. Hiramitsu, K. Futamura, M. Okada, M. Tsujita, T. Ichimori, N. Goto, S. Narumi, Y. Watarai.

    Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.

    BackgroundRecently, complex living donors with marginal factors including hypertension, dyslipidemia, glucose intolerance, and obesity are increasing. Postoperative kidney function of living donors for kidney transplantation…
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