2018 American Transplant Congress
Implementing Mobile Health Technology for Living Kidney Donor Follow-Up: Transplant Provider Perspectives
Transplant hospitals are required to collect and report living kidney donor (LKD) follow-up data at 6-months, 1-year, and 2-years, but fewer than 50% of hospitals…2018 American Transplant Congress
Biomaterial-Based Localized and Controlled Delivery of Tofacitinib to Actuate Enhanced Costimulation Blockade and Promote Long-Term Transplant Survival
Complications from long-term use of calcineurin inhibitors remain a major issue for transplant patients and alternative therapies are highly needed. We investigated two innovative drug…2018 American Transplant Congress
T Cell Immunomonitoring Including Donor Specific Treg Expansion Prospectively Predicts Renal Allograft Tolerance Induced by Transient Mixed Chimerism
Center for Transplant Science, Massachusetts General Hospital, Boston, MA.
Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…2018 American Transplant Congress
NOS2 Deficiency Limits Long Term Survival of Murine Kidney Allografts
Nitric oxide (NO) is a small molecule derived from L-arginine that governs a myriad of physiologic processes including the antimicrobial and tumoricidal responses. Although NO…2018 American Transplant Congress
Reduction in Circulating CD19+CD24+CD27+ Regulatory B Cell Frequency Predicts Acute Rejection in Liver Transplant Patients
Liver Transplant Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Background: Accumulating evidence suggests that regulatory B cells (Bregs) play an important role in modulating inflammation and autoimmune diseases. However, whether Bregs regulate acute liver…2018 American Transplant Congress
Human Urine-Derived Stem Cells Protect Renal Function by Releasing miR-129-5p Which Targets High-Mobility Group Box-1 (HMGB1) in Rat Ischemia Reperfusion Injury Model
Objective: This study investigated the protective effect of human urine-derived stem cells (USCs) on renal ischemia reperfusion injury (IRI) in rats. Methods: Human USCs was…2018 American Transplant Congress
Geographic Variation in the Treatment of Adult Heart Transplant Candidates in the US
1University of Chicago, Chicago, IL; 2Northwestern University, Chicago, IL.
The current priority ranking system for US heart transplant candidates is based on treatment intensity which may encourage the overtreatment of relatively stable candidates. We…2018 American Transplant Congress
Lymphocyte Proportions Post Thymectomy Are Associated with Allergic Disorders in Heart Transplanted Children
Background: Allergic disorders are more common in pediatric heart transplant (HTx) recipients than non-transplanted children, with young age at HTx and thymectomy being risk factors.…2018 American Transplant Congress
Combined Heart–Kidney Compared to Isolated Heart Transplant in Patients with Chronic Kidney Disease – A Single Center Experience
Tufts University School of Medicine, Boston, MA.
Background: Severe irreversible renal dysfunction has been a contraindication for heart transplant (HTx); however, combined heart-kidney transplant (HKTx) is an accepted therapeutic option for concomitant…2018 American Transplant Congress
Analysis of Human Islet Damage during In Vitro Culture Using miRNA 375
BackgroundIslet culture prior to transplantation has been shown to facilitate recovery, reduce immunogenicity, suppress exocrine contamination and provides flexibility for evaluation of islets and preparation…
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