Am J Transplant, Volume 18, Suppl 3 Archives - Page 58 of 211 - ATC Abstracts

2018 American Transplant Congress
Long-Term Outcomes and Predictors of Survival after Liver Transplantation for Wilson Disease (WD)
P. Jalal, S. May, A. Rana.
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Background/Aims: Orthotopic liver transplantation (OLT) is life-saving for patients with liver failure from Wilson Disease (WD). Our goal was to evaluate patient and graft survival…
2018 American Transplant Congress
Associations of Poor Physical and Cognitive Performance and Kidney Transplant Waiting List Denial
M. Harhay,¹ K. Ranganna,¹ F. Michie,¹ C. Selinski,¹ T. Bajakian,¹ L. Levin Mizrahi,¹ J. Lee,¹ G. Malat,¹ G. Xiao,¹ D. Reich,¹ S. Guy,¹ P. Reese.²
¹Drexel University College of Medicine, Philadelphia; ²Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Background: Little is known about the clinical impacts of physical and cognitive impairments on kidney transplantation (KT) candidacy.Methods: We enrolled 170 adults (age> 18 years)…
2018 American Transplant Congress
Challenges in Cultural and Linguistic Discordance in Caring for Somali Kidney Transplant Recipients at a Large-Volume Transplant Center
K. Peterson,¹ O. Serrano,¹ M. Odegard,¹ S. Mongin,² D. Berglund,³ D. Vock,⁴ S. Chinnakotla,¹ T. Dunn,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas.¹
¹Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN; ³Informatics Services for Research and Reporting, Fairview Health Services, Minneapolis, MN; ⁴Division of Biostatistics, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Kidney Transplantation (KT) demands navigation of a complex healthcare system and adherence to lifelong immunosuppression therapy. Cultural and linguistic discordance between patients and providers…
2018 American Transplant Congress
Decline in Pancreas Transplantation Numbers is Accompanied with Lower Publication Rates
S. Benjamens,¹ C. Margreiter,² E. de Koning,³ H. Leuvenink,¹ R. Pol.¹
¹University Medical Center Groningen, Groningen, Netherlands; ²Medical University Innsbruck, Innsbruck, Austria; ³Leiden University Medical Center, Leiden, Netherlands.
Introduction: After several years of growth in many pancreas transplant (PTx) programs, the United Network for Organ Sharing (UNOS) reports a decline in PTx numbers…
2018 American Transplant Congress
Pancreas and Kidney Co-Transplantation in Type II Diabetes: A Single Center Experience
J. Choi, J. Jung, H. Kwon, S. Shin, Y. Kim, D. Han.
Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University Ulsan College of Medicine, Seoul, Korea.
Background: Diabetic CKD patients present increased morbidity and mortality due to cardiovascular complications. Pancreas transplantation can restore insulin independence in patients with type I diabetes…
2018 American Transplant Congress
Trends in Safety Reporting to UNOS by Event Type
A. Doyle,¹ S. Tlusty,² R. Urban,² M. Marvin,³ E. Hollinger,⁵ D. Marshman,⁴ M. Green.⁵
¹Medicine, University of Virginia, Charlottesville, VA; ²UNOS, Ichmond, VA; ³Surgery, Geisinger, Davville, PA; ⁴LifeLink Foundation, Norcross, GA; ⁵Surgery, University of Pittsbugh, Pittsburgh, PA; ⁶Surgery, Rush Medical Center, Chicago, IL.
The UNOS Operations and Safety Committee is charged with reviewing reported patient safety situations, identifying safety gaps, addressing high frequency and high impact events, and…
2018 American Transplant Congress
Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control
S. Dionne,² K. Klama,² H. Rashid,² A. Niedzinski.²
¹Quality Assurance, LABS, Inc., Centennial, CO; ²Infectious Disease, LABS, Inc., Philadelphia, PA.
Background: Our STAT donor-screening lab implemented a new LIMS that is used to manage patient orders, testing and reporting. We intentionally customized the LIMS to…
2018 American Transplant Congress
The Regulatory Role of Plasma Cells (as Bregs) is Counterbalanced by a NOVEL Inflammatory Role in Murine Transplant and Autoimmune Models
Z. Song,^1,2 Y. Zhou,² Q. Ding,¹ D. Rothstein.¹
¹Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh; ²School of Medicine, Tsinghua University, Beijing, China.
Plasma Cells (PCs; B220lowCD138hiBlimp1+Ig+) in LN and spleen were shown to be the major source of B cell lineage IL-10, and absence of PCs worsens…
2018 American Transplant Congress
CD4⁺CD25^bright Regulatory T Cells Prevent Acute Xenogeneic GVHD
Y. Huang, A. Merchak, H. Xu, A. Chhabra, A. Khalil, Y. Wen, M. Binion, M. Badder, L. Kahn, S. Ildstad.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
Graft-versus-host disease (GVHD) is a major complication and limitation to the broad application of hematopoietic stem cell transplantation. Cell therapy has emerged as a promising…
2018 American Transplant Congress
Galangin Promotes Treg Development and Function
F. Liang,¹ H. Fang,¹ R. Zhang,¹ Q. Chen,² J. Ochando,³ Y. Ding,¹ J. Xu.¹
¹Department of Immunology, Capital Medical University, Beijing, China; ²Department of Thoracic Surgery, Chaoyang Hospital, Beijing, China; ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Introduction: FoxP3+ Treg cells are central in controlling immune responses and transplant tolerance. CD73 (ecto-5'-nucleotidase), which serves to convert AMP to adenosine, is essential for…