Am J Transplant, Volume 18, Suppl 3 Archives - Page 56 of 211 - ATC Abstracts

2018 American Transplant Congress
Implementation of the Lung Allocation Score is Associated with Decreased Mortality in Combined Liver-Lung Allograft Recipients
K. Freischlag,¹ P. Shroder,² B. Ezekian,² M. Mulvihill,² S. Knechtle.²
¹School of Medicine, Duke University, Durham, NC; ²Surgery, Duke University, Durham, NC.
Objective: The current system for simultaneous liver-lung transplant (LLT) generally matches a recipient with a donor based on his or her lung allocation score (LAS),…
2018 American Transplant Congress
Treg Regulate Distinct Lymphatic NFκB Signaling Pathways to Alter Migration and Immunity
W. Piao, Y. Xiong, L. Li, V. Saxena, J. Bromberg.
UMB, MD.
Background: Treg migration to the graft and draining lymph nodes is crucial for graft survival. Little is known about the molecular cues that regulate the…
2018 American Transplant Congress
Clinical Outcomes, Care Needs and Adherence in Long Term Intestine Transplant Survivors ≥10 yrs
B. Kosmach-Park,¹ G. Mazariegos.²
¹Transplant Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ²Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
Background: Although survival has increased significantly for pediatric ITx recipients, continued graft surveillance and monitoring of clinical and psychosocial outcomes are essential. Purpose: Describe clinical…
2018 American Transplant Congress
Impact of High Dose Acyclovir Cytomegalovirus Prophylaxis Failure in Abdominal Solid Organ Transplant Recipients
J. Fose, M. Jorgenson, M. Siodlak, G. Leverson, J. Smith, R. Redfield.
University of Wisconsin Hospital and Clinics, Madison; University of Wisconsin-Madison School of Medicine and Public Health, Madison.
Purpose: To describe the long-term clinical impact of high-dose acyclovir (HD-A, 800 mg 4 times daily) cytomegalovirus (CMV) prophylaxis failure in the seropositive (R+) abdominal…
2018 American Transplant Congress
Bloodstream Infection Caused by Enteric Organisms during the First 6 Months after Intestinal Transplant
J. Simkins,¹ J. Morillas-Rodriguez,¹ M. Morris,¹ L. Abbo,¹ J. Camargo,¹ R. Vianna.²
¹Medicine/Infectious Diseases, University of Miami, Miami; ²Surgery, University of Miami, Miami.
Background: Irreversible intestinal failure can be treated effectively with intestinal transplant (ITx). Infections are common after ITx but data on bloodstream infection (BSI) due to…
2018 American Transplant Congress
Targeting Plasma Cells with Anti-CD38mAb (Daratumumab) and CXCR4 Antagonist (Plerixafor) for Desensitization
J. Kwun,¹ E. Brian,¹ M. Manook,¹ J. Park,¹ K. Freischlag,¹ J. Yoon,¹ J. Yi,¹ M. Stegall,² S. Knechtle.¹
¹Surgery, Duke University, Durham, NC; ²Surgery, Mayo Clinic, Rochester, MN.
[Introduction] Sensitized patients comprise a significant portion (30%) of candidates on the transplant waiting list. Unfortunately for sensitized patients, the presence of donor-specific antibodies (DSA)…
2018 American Transplant Congress
Donor Transmitted Nut Allergy Following Solid Organ Transplantation: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
R. Bag, S. Tlusty, G. Vece, T. Peterson, J. Schaenman, G. Berry, J. Bucio, L. Danziger-Isakov, D. Florescu, D. Goldberg, C. Ho, R. La Hoz, K. Lilly, M. Malinis, A. Mehta, M. Nalesnik, R. Sawyer, L. Strasfeld, P. Wood, N. Theodoropoulos, M. Michaels, C. Wolfe.
DTAC, United Network for Organ Sharing, Richmond.
Introduction: Transplant Acquired Food Allergy may cause fatal allergic reactions, and is an under-recognized and poorly understood. Specifically, nut allergy transfer after solid organ transplantation…
2018 American Transplant Congress
Mycophenolic Acid Reduces BK Polyomavirus Replication in an In Vitro Model of Renal Tubular Epithelial Cells Infection
E. Favi,¹ S. Delbue,² C. Colico,¹ P. Ferrante,² S. Villani,² I. Perna,² N. Mondoni,² A. Giussani,¹ M. Ferraresso.¹
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; ²Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Background. BK virus (BKV) nephropathy is an important cause of allograft failure after kidney transplant. Immunosuppression is a recognized risk factor for BKV replication but…
2018 American Transplant Congress
Increased Expression of CEACAM1 is Cytoprotective during Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation
R. Sosa,¹ J. Nevarez-Mejia,¹ M. Rossetti,¹ A. Zarrinpar,² F. Kaldas,² C. Lassman,¹ B. Naini,¹ N. Datta,² R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,² E. Reed.¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²Surgery, University of California, Los Angeles, Los Angeles, CA.
Background T cell exhaustion has recently been proposed as an alternative mechanism to prevent memory development and tissue damage arising during ischemia-reperfusion injury (IRI) in…
2018 American Transplant Congress
A Phase I/II, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients
S. Jordan,¹ J. Choi,¹ O. Aubert,² M. Haas,³ A. Loupy,² E. Huang,¹ A. Peng,¹ I. Kim,¹ S. Sethi,¹ S. Louie,¹ D. Puliyanda,¹ A. Vo.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Paris Translational Research Center for Organ Transplantation, Necker Hospital, Paris, France; ³Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Delayed graft function (DGF)in kidney allograft recipients is traditionally defined as need for dialysis during the first week after transplantation. DGF is related to…