ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Pancreas Transplant Alone (PTA) Outcome is Best in Brittle Diabetic Patients without Advanced Nephropathy

    M. Laftavi,1 A. Gruessner,2 O. Pankewycz,1 B. Kaylene,2 S. Sidharth,2 R. Gruessner.

    1SUNY Upstate Medical University, Syracuse, NY; 2SUNY Downstate Medical Center, Brooklyn, NY.

    Introduction: Although the overall number of pancreas transplants in combination with or after a kidney transplant have declined, the number of PTA has remained relatively…
  • 2018 American Transplant Congress

    Lab Turnaround Times: A Performance Improvement Project in Post Kidney/Pancreas Transplant Clinic

    M. Farrell, S. Kapadia.

    Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles; Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles.

    Purpose:Patients' routine labs, including immunosuppression drug levels, are drawn with each clinic visit starting at 6am.Because the drug levels are not reported by the time…
  • 2018 American Transplant Congress

    A Transcriptomic Signature in PBMC from Kidney Transplant Recipients at Baseline Predicts Early Acute Rejection

    W. Zhang,1 Z. Yi,1 P. Cravedi,1 L. Li,1 K. Keung,2 C. Wei,1 M. Menon,1 J. Dudley,1 P. O'Connell,2 B. Murphy.1

    1Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; 2Medicine, The University of Sydney, Sydney, Australia.

    Background: Our multi-center study (Genomics of Chronic Allograft Rejection, GoCAR) revealed that early acute rejection (EAR, developed before 6 months post-transplant) is associated with later…
  • 2018 American Transplant Congress

    Skeletons in the Closet? An Insight into Donor Liver Discards in the US

    K. Halazun, A. Rana, G. Roll, P. Tabrizian, V. Agopian, B. Samstein, R. Brown, J. Emond.

    Weill Cornell Medicine, NY, NY.

    Background Liver discards are poorly investigated. Among these discarded livers are potentially useable grafts that could save the lives of many of the 2500-3000 who…
  • 2018 American Transplant Congress

    Natural History and Determinants of Infectious Complications after Kidney Transplantation: A Nationwide Prospective Population Based Cohort

    A. Scelma, M. Perrier, O. Lortholary, S. Girerd, C. Kerleau, V. Garrigues, F. Buron, N. Kamar, C. Legendre, Y. Bouatou, C. Lefaucheur, M. Giral, A. Loupy.

    Paris Transplant Group, Paris, France.

    Background: Although Infectious complications are a major cause of morbidity and mortality in KTR, little is known about their natural history and determinants at a…
  • 2018 American Transplant Congress

    Identification of Noninvasive and Mechanistically-Informative Biomarkers Predictive of Reversal of Acute Cellular Rejection (ACR) in Kidney Allografts

    D. Luan,1 J. Schwartz,2 R. Ding,2 T. Muthukumar,2 D. Dadhania,2 M. Suthanthiran.2

    1University of Michigan, Ann Arbor, MI; 2Weill Cornell Medical College, New York City, NY.

    Objective: We determined whether urinary cell mRNAs predict response to anti-rejection therapy in kidney allograft recipients with Banff grade IA or higher ACR biopsies.Methods: We…
  • 2018 American Transplant Congress

    Balloon-Occluded Retrograde Transvenous Obliteration (BRTO) for the Treatment of Medically Refractory Hepatic Encephalopathy (HE) in Patients with ESLD and Significant Portal-Venous Shunting

    N. Presser, J. DiNorcia, V. Agopian, H. Yersiz, D. Farmer, R. Busuttil, F. Kaldas.

    Liver and Pancreas Transplantation, Dumont-UCLA Liver Transplant Center, Los Angeles, CA.

    Background: Patients with medical refractory HE represent a challenging group of patients. Plagued by repeated hospitalizations, long lengths of stay (LOS) and high healthcare costs,…
  • 2018 American Transplant Congress

    Improved Long-Term Outcomes of Pancreas Transplantation: Analysis of Allograft Half-Lives and Predictive Demographic Factors

    A. Adamusiak, R. Kandaswamy, T. Dunn, S. Riad, E. Finger.

    Department of Surgery Division of Transplantation, University of Minessota, Minneapolis, MN.

    In contrast to other solid organ transplants, the characteristics of long term surviving pancreas transplants have not been well described. Our objective was to measure…
  • 2018 American Transplant Congress

    Engineering Regulatory T Cells with Interleukin (IL-)2 Nanogel for Improved Alloimmune Suppression

    S. Eskandari,1 M. Bandeira Melo,2 J. Assaker,1 A. Mansouri,1 S. Cai,1 B. Al Dulaijan,1 M. Mohamed,1 D. Irvine,2 J. Azzi.1

    1Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 2Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA.

    Clinical trials of adoptively transferred regulatory T cells (TRegs) have been hindered by the short lifespan of these transferred TRegs. Systemic injection of low-dose interleukin…
  • 2018 American Transplant Congress

    Waitlist Survival is Approaching Survival after Kidney Transplantation

    A. Rana, B. Murthy, C. O'Mahony, J. Goss.

    Abdominal Tranplantation, Baylor College of Medicine, Houston, TX.

    Backround: Kidney transplantation confers a significant survival benefit to its recipients. Our objective was to reassess this survival benefit in light of improving outcomes on…
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