2018 American Transplant Congress
Quality of Social Support Network and Access to Transplant: What Matters?
Recovery after kidney transplant (KT) requires adequate social support. Caregivers are asked to attend transplant evaluation and complete a caregiver contract. Little is known about…2018 American Transplant Congress
Long-Term Follow-Up of Patients with Primary Sclerosing Cholangitis Undergoing Liver Transplantation with Duct-to-Duct Biliary Reconstruction
Transplant Surgery, Cleveland Clinic, Cleveland, OH.
Background:Reconstruction of biliary drainage after liver transplantation (LTx) in patients with primary sclerosing cholangitis (PSC) has been a matter of controversy. Over the recent years,…2018 American Transplant Congress
T-Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell Generation and Regulatory-T-Cell-Dependent Cardiac Allograft Survival
C5aR2 (C5L2/gp77) is a transmembrane receptor that binds C5a but lacks motifs needed to induce G-protein coupled signal transduction. C5aR2 modulates various inflammatory diseases in…2018 American Transplant Congress
Induction Agents and Post-Transplant Malignancies in Kidney Transplants: An Examination of Outcomes at a Large Volume Center over 20 Years
Division of Transplant Surgery, University of Wisconsin, Madison, WI.
Introduction: Induction agents have a profound effect on the immune milieu at the time of kidney transplantation. However, evaluation of their long-term effects on graft…2018 American Transplant Congress
RNA Expression Profiling of Renal Allografts in a Non-Human Primate Identifies Inflammation as a Risk Factor in Chronic Antibody Mediated Rejection
IntroductionChronic alloantibody mediated rejection (CAMR) is a major risk factor in renal allografts. Some inflammation is commonly identified within CAMR, though mostly low grade, and…2018 American Transplant Congress
The Mark of Zorro: IL35-Coated Exosomes Cross-Dress and Exhaust Recipient T & B Cells during Transplant Tolerance
The folk-hero "Zorro" left his mark on by a sword-slashed "Z". In transplant recipients, rare Tregs also leave a mark on their conventional T &…2018 American Transplant Congress
Comparison of Three Approaches for Laparoscopic Donor Nephrectomy: Transvaginal, Transumbilical Single Site and Retroperitoneal
Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Reduction of burdens to live kidney donors are important. The aim of this study was to compare the surgical outcomes of 3 approaches we…2018 American Transplant Congress
Endothelial Cell Heterogeneity Governs Basal and Inducible Inflammatory Responses Relevant to Allograft Injury
Pathology and Laboratory Medicine, UCLA, Los Angeles, CA.
PurposeTransplanted tissues are differentially susceptible to ischemia/reperfusion and rejection. Endothelial cells (EC) are active regulators of inflammation. But model EC may not adequately reflect the…2018 American Transplant Congress
Validation of an Integrative and Dynamic Prognostic Score for Response to Therapy in Solid Organ Transplants
Paris Translational Center for Organ Transplantation, Paris, France.
Drug development in transplantation has diminished due to the lack of suitable endpoints for predicting graft failure. We sought to validate the performance of an…2018 American Transplant Congress
Pre-Donation Body Mass Index Associations with Outcomes in Living Kidney Donors: A Single Centre Experience
West London Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
Background. Living kidney donor (LD) eligibility criteria have expanded as a result of excellent donor outcomes and increasing organ demand. However, considerable variability exists between…
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