Am J Transplant, Volume 18, Suppl 3 Archives - Page 55 of 211 - ATC Abstracts

2018 American Transplant Congress
Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus
H. Joharji, A. Al-Jedai, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. El-Siesy, M. Al-Sebayel, H. Al-Ashgar, M. Al-Quaiz, W. Alhomodi, A. Aloubal, A. Almohishir.
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of genotype 4 HCV has shifted to interferon free…
2018 American Transplant Congress
Technical Aspects of Orthotopic Liver Transplantation – A Survey-Based Study within the Eurotransplant, Swisstransplant, Scandiatransplant and British Transplantation Society Networks
Z. Czigany,¹ J. Bednarsch,¹ J. Böcker,¹ F. Meister,¹ I. Amygdalos,¹ W. Schöning,¹ T. Ulmer,¹ X. Rogiers,² P. Dutkowski,³ P-.D. Line,⁴ M. Malagó,⁵ U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Solid Organ Transplantation, University Hospital Gent, Gent, Belgium; ³Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland; ⁴Department of Solid Organ Transplantation, University Hospital Oslo, Oslo, Norway; ⁵Department of Hepatobiliary Surgery and Transplantation, University College London, London, United Kingdom.
Background: Surgical aspects of ortoptopic liver transplantation (OLT) are widely based on low-level evidence as well as on local institutional protocols. Aim of this study…
2018 American Transplant Congress
Defective Innate Immune Response to Opportunistic Pathogens in Cytomegalovirus-Infected Monocytes
P. Sen, A. R. Wilkie, R. Fernandes, R. J. Lane, S. E. Hickman, T. K. Means, E. R. Rosenberg, D. M. Coen, J. A. Fishman, J. El Khoury.
Transplant and Immunocompromised Group, Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA; Department of Biological Chemistry and Pharmacology, Harvard Medical School, Boston, MA.
Human cytomegalovirus (CMV) is the most common infection encountered in transplantation and is an important cause of morbidity and mortality in both solid organ and…
2018 American Transplant Congress
Weight Changes before and after Kidney Donation
A. Bugeja,¹ S. Harris,² J. Ernst,¹ K. D. Burns,¹ G. Knoll,¹ E. G. Clark.¹
¹Medicine, The Ottawa Hospital, Ottawa, ON, Canada; ²Faculty of Science, University of Ottawa, Ottawa, ON, Canada.
IntroductionLiving kidney donors remain at low risk of end stage kidney disease but obese and overweight donors' risk is increased. We aimed to describe the…
2018 American Transplant Congress
Donor Deficiency of RIP3 Phosphokinase Activity Shortens Cardiac Allograft Survival in the Setting of Costimulation Blockade
M. Zhu, K. Samy, L. Lin, J. Wang, L. Cendales, A. Kirk, A. Barbas, T. Brennan.
Surgery, Duke University, Durham, NC.
Receptor-interacting protein kinase 3 (RIP3) is critical for necroptosis in the setting of inflammation. It has been shown that kidney and heart allografts deficient in…
2018 American Transplant Congress
Pre-Transplant Assessment of AMR Risk by Novel Donor/recipient Non-HLA Variants
S. Pineda,¹ T. Sigdel,¹ J. Chen,¹ A. Jackson,² M. Sirota,¹ M. Sarwal.¹
¹UCSF, San Francisco; ²Johns Hopkins University, Baltimore.
Transplant (tx) injury from antibody mediated (AMR) and T cell mediated (CMR) rejection, limits indefinite survival after HLA mismatched organ tx. AMR is incompletely diagnosed…
2018 American Transplant Congress
Mortality and Kidney Transplantation Outcomes among Chronic Dialysis Patients Who Are Seropositive for Hepatitis C Virus
D. Sawinski,¹ F. Kimberly,¹ L. Vincent,¹ S. Justine,¹ B. Colleen,¹ C. Jordana,¹ G. David,¹ L. Jayme,² W. Joe,³ R. Peter.¹
¹Univ of Pennsylvania, Philadelphia, PA; ²Univ of Alabama, Birmingham, AL; ³DaVita, Minneapolis, MN.
Hepatitis C virus (HCV) infection is common among patients receiving chronic dialysis. However, few studies have examined both survival on dialysis as well as transplantation…
2018 American Transplant Congress
Safety and Efficacy of Tocilizumab (anti-IL6R, TCZ) Therapy in the Treatment of Chronic Antibody Mediated Rejection (cABMR) in Pediatric Renal Transplant Recipients
D. Puliyanda, I. Kim, J. Choi, M. Haas, X. Zhang, A. Vo, H. Pizzo, S. Jordan.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA.
Background: Development of de novo Donor specific antibodies (DSA) post renal transplantation puts pediatric patients(pts) at risk for ABMR and allograft failure (Kim JJ AJT…
2018 American Transplant Congress
Complex Combined Thoracic/liver Transplant: A Seven Year Experience
N. Presser, J. DiNorcia, V. Agopian, H. Yersiz, D. Farmer, R. Busuttil, F. Kaldas.
Liver and Pancreas Transplant, UCLA, Los Angeles, CA.
Background: While rare, combined Thoracic/Liver transplants are employed with increasing frequency. Consistent data regarding the technical conduct, patient selection and outcomes in this highly complex…
2018 American Transplant Congress
The Role of CD46 in Early Islet Engraftment in a Dual Transplant Model
Q. Gao, K. Samy, R. Davis, M. Song, A. MacDonald, F. Leopardi, T. How, K. Williams, G. Devi, B. Collins, A. Kirk.
Department of Surgery, Duke University School of Medicine, Durham, NC.
IntroductionMembrane cofactor protein (CD46) is known to attenuate the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46…