ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immune Regulatory Proteins in Lung Transplant Recipient with Primary Graft Dysfunction

    M. Sharma, S. Biswas Roy, R. Walia, A. Omar, R. Bremner, M. Smith, T. Mohanakumar.

    Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix.

    Background: Circulating exosomes isolated from lung transplant recipients (LTxRs) with acute or chronic rejection contains lung self-antigens (SAgs), K alpha 1 tubulin (Kα1T) and collagen…
  • 2018 American Transplant Congress

    Treatment of Active Chronic Antibody-Mediated Rejection with Rituximab, IVIG and Plasma Exchange

    G. Piñeiro,1 J. Rovira,2 E. De Sousa-Amorim,1 J. Villarreal,1 M. Sole,3 I. Revuelta,1 M. Lozano,4 E. Palou,4 F. Oppenheimer,1 J. Campistol,1 F. Diekmann.1,2

    1Nephrology and Renal Transplantation, Hospital Clinic de Barcelona, Barcelona, Spain; 2Laboratori Experimental de Nefrologia i Trasplantament (LENIT), Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain; 3Pathology, Hospital Clinic de Barcelona, Barcelona, Spain; 4Apheresis Unit, Hemotherapy and Hemostasis, Hospital Clinic de Barcelona, Barcelona, Spain; 5Immunology, Hospital Clinic de Barcelona, Barcelona, Spain.

    Chronic antibody-mediated rejection (cABMR) and transplant glomerulopathy (TG) are main features associated with long-term graft loss. Despite its clinical significance, the available evidence on treatment…
  • 2018 American Transplant Congress

    Association of Health Literacy with Adverse Outcomes among Kidney Transplant Candidates and Recipients

    F. Warsame, C. Haugen, J. Garonzik-Wang, N. Desai, D. Crews, T. Purnell, M. McAdams-DeMarco, D. Segev.

    Johns Hopkins University, Baltimore, MD.

    Limited health literacy (LHL) is known to adversely affect health outcomes in patients managing chronic illness. We aimed to examine the association between LHL, listing,…
  • 2018 American Transplant Congress

    Outcomes in Liver and Combined Liver-Kidney Retransplantation

    D. Sonnier, D. Bruce, H. Bohorquez, E. Bugeaud, I. Carmody, A. Cohen, A. Mathur, J. Seal, G. Loss.

    Department of Surgery/Transplantat, Ochsner Clinic, New Orleans, LA.

    Many centers consider liver retransplantation controversial due to poor outcomes and high resource requirement. In the setting of renal failure and high MELD, many are…
  • 2018 American Transplant Congress

    Providing Actual Echocardiographic Images to Centers Markedly Increases Transplantation of Deceased Donor Hearts

    J. Trageser, C. Wainaia, L. Stocks, R. Steiner.

    Organ Procurement, Lifesharing of San Diego, San Diego, CA.

    US transplant centers are cautious in accepting deceased donor hearts (DDHs). Even in previously healthy, young brain dead donors, wall motion and other echographic abnormalities…
  • 2018 American Transplant Congress

    Impact of Antecedent Malignancy on Kidney Transplant Outcomes: Patient, Graft, and Cancer-Free Survival

    O. Serrano,1 S. Mongin,2 D. Berglund,1 D. Vock,3 S. Chinnakotla,1 T. Dunn,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas.1

    1Surgery, University of Minnesota, Minneapolis, MN; 2Biostatistical Design and Analysis Center, Clinical and Translational Science Institute, Minneapolis, MN; 3Biostatistics, University of Minnesota, Minneapolis, MN.

    OBJECTIVE: Non-skin pretransplant malignancy (NSPTM) has historically been considered a relative contraindication to kidney transplantation (KT). In addition to the conventional risk factors for cancer,…
  • 2018 American Transplant Congress

    “Majority Rules”: A Method to Reduce Variability in Diagnosing Antibody Mediated Rejection in Renal Allograft Biopsies Using Banff 2013

    B. Smith,1 L. Cornell,1 M. Smith,2 C. Cortese,3 X. Geiger,3 C. Schinstock,1 W. Kremers,1 M. Stegall.1

    1Mayo Clinic, Rochester, MN; 2Mayo Clinic, Scottsdale, AZ; 3Mayo Clinic, Jacksonville, FL.

    Introduction: The Banff 2013 criteria for diagnosing antibody-mediated rejection (ABMR) includes three lesions: glomerulitis (g), peritubularitis (PTC), and chronic glomerulopathy (cg). The poor reproducibility of…
  • 2018 American Transplant Congress

    Therapeutic Drug Monitoring (TDM) of Suspension (SUS), Extended-Release (ER), and Intravenous (IV) Posaconazole (POS) at a Large Transplant Center

    G. Haidar, R. Shields, C. Clancy, M. Nguyen.

    Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.

    Background: Data on ER and IV POS among organ transplant recipients (OTRs) are limited, and the role of TDM is unclear.Methods: Retrospective study of patients…
  • 2018 American Transplant Congress

    Simultaneous versus Pretransplant Native Nephrectomy in Autosomal Dominant Polycystic Kidney Disease Patients

    M. Eltemamy, A. Crane, M. Elmer-Dewitt, B. Frainey, A. Elshafei, A. Wee, D. Goldfarb, V. Krishnamurthi.

    Cleveland Clinic, Cleveland.

    Introduction: 50% of autosomal dominant polycystic kidney disease (ADPKD) patients will develop ESRD. For those patients who undergo renal transplantation (RT) and require a native…
  • 2018 American Transplant Congress

    Serum Cytokines as Markers of Influenza Infection Outcomes after Transplantation

    A. L'Huillier,1 V. Ferreira,1 C. Hirzel,1 E. Cordero,2 A. Limaye,3 G. Reid,4 J. Englund,3 E. Blumberg,5 A. Humar,1 D. Kumar.1

    1UHN, Toronto, Canada; 2REIPI, Seville, Spain; 3UOWMC, Seattle; 4LUMC, Chicago; 5UPenn, Philadelphia.

    Background:Influenza infection in transplant patients can be severe but factors predictive of outcome in this setting are unclear. The aim of the study was to…
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