ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Therapeutic Drug Monitoring (TDM) of Suspension (SUS), Extended-Release (ER), and Intravenous (IV) Posaconazole (POS) at a Large Transplant Center

    G. Haidar, R. Shields, C. Clancy, M. Nguyen.

    Medicine, Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA.

    Background: Data on ER and IV POS among organ transplant recipients (OTRs) are limited, and the role of TDM is unclear.Methods: Retrospective study of patients…
  • 2018 American Transplant Congress

    Simultaneous versus Pretransplant Native Nephrectomy in Autosomal Dominant Polycystic Kidney Disease Patients

    M. Eltemamy, A. Crane, M. Elmer-Dewitt, B. Frainey, A. Elshafei, A. Wee, D. Goldfarb, V. Krishnamurthi.

    Cleveland Clinic, Cleveland.

    Introduction: 50% of autosomal dominant polycystic kidney disease (ADPKD) patients will develop ESRD. For those patients who undergo renal transplantation (RT) and require a native…
  • 2018 American Transplant Congress

    Serum Cytokines as Markers of Influenza Infection Outcomes after Transplantation

    A. L'Huillier,1 V. Ferreira,1 C. Hirzel,1 E. Cordero,2 A. Limaye,3 G. Reid,4 J. Englund,3 E. Blumberg,5 A. Humar,1 D. Kumar.1

    1UHN, Toronto, Canada; 2REIPI, Seville, Spain; 3UOWMC, Seattle; 4LUMC, Chicago; 5UPenn, Philadelphia.

    Background:Influenza infection in transplant patients can be severe but factors predictive of outcome in this setting are unclear. The aim of the study was to…
  • 2018 American Transplant Congress

    Factor Analysis (FA) of Renal Transplant Biopsy (KTxBx) Data Enables Objective Assessment of Risk for Subsequent Death Censored Graft Failure (DCGF)

    L. Hunsicker,1 J. Grande,2 J. Cecka,3 A. Matas,4 The DeKaf Consortium.

    1Int. Med., UIowa, Iowa City, IA; 2Pathology, Mayo Clinic, Rochester, MN; 3Immunogenetics, UCLA, Los Angeles, CA; 4Surgery, U Minnesota, Minneapolis, MN.

    We examined the impact of five axes of injury identified by FA in the KTxBx on the hazard for subsequent DCGF in two DeKAF cohorts.Methods:…
  • 2018 American Transplant Congress

    Morbidity Outcomes in Live Kidney Donors in the UK: 15 Year Compartive Cohort Study

    N. Krishnan,1 L. Mumford,3 G. Lipkin,4 S. Fletcher,1 I. Dasgupta,5 P. Gill,6 R. Ryan,7 N. Raymond.8

    1Renal Unit, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; 2Faculty of Health and Life Sciences, Coventry University, Coventry, United Kingdom; 3Statistics and Clinical Studies, Organ Donation and Transplant, National Health Services Blood and Transplant, Bristol, United Kingdom; 4Renal Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; 5Renal Unit, Heart of England Hospitals, Birmingham, United Kingdom; 6Academic Unit of Primary Care, University of Warwick, Coventry, United Kingdom; 7Primary Care, West Midlands, Birmingham, United Kingdom; 8Statistics, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom.

    Understanding risks and long-term outcomes of live kidney donation is essential.To investigate longer-term morbidity outcomes of live kidney donors (LD) compared to healthy controls.Ethics approval…
  • 2018 American Transplant Congress

    Robotic Kidney Transplantation in Obese Recipients: The New Standard?

    I. Tzvetanov, C. Di Bella, K. Tulla, M. Spaggiari, F. Gheza, P. Di Cocco, J. Oberholzer, E. Benedetti.

    Surgery, University of Illinois, Chicago, IL; Surgery, University of Virginia, Virginia, VA.

    Introduction: Obese recipients could potentially benefit from the introduction of minimally invasive techniques for kidney transplantation. We have introduced robotic kidney transplantation for our obese…
  • 2018 American Transplant Congress

    Outcomes of Pediatric Donor Liver Grafts for Adult Transplantation: A National Analysis

    J. Yerxa, Q. Gao, U. Scheuermann, R. Davis, D. Vikraman, A. Barbas.

    Surgery, Duke University, Durham, NC.

    Introduction: Utilization of pediatric donor organs for adult transplant has emerged in recent years in response to organ shortage. In this study, we investigate recipient…
  • 2018 American Transplant Congress

    Cognition and Self-Management in Liver Transplant Recipients

    D. Ko,1 L. Bratzke,2 R. Muehrer.2

    1Vanderbilt University, Nashville; 2University of Wisconsin-Madison, Madison.

    Cognitive impairment in the liver transplant (LT) population could negatively affect one's ability to self-manage. This study examined cognition and its relationship with self-management in…
  • 2018 American Transplant Congress

    Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells

    A. Suah,1 S. Khiew,1 J. Young,1 D. Yin,1 Q. Wang,1 M. Alegre,2 A. Chong.1

    1Surgery, Univeristy of Chicago Medicine, Chicago, IL; 2Medicine, University of Chicago, Chicago, IL.

    Introduction: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models indicates it induces fetal-specific regulatory T cell (Treg) expansion…
  • 2018 American Transplant Congress

    Respiratory Viral Infections Induces Exosomes and Antibodies to Lung Self-Antigens, Kα1Tubulin and Collagen V, Following Human Lung Transplantation

    M. Gunasekaran,1 S. Bansal,1 M. Sharma,1 R. Walia,1 R. Hachem,2 A. Limaye,3 R. Bremner,1 M. Smith,1 T. Mohanakumar.1

    1St. Joseph's Hosp & Med Ctr, Phoenix; 2Washington Univ Sch Med, St. Louis; 3Univ Washington, Seattle.

    Respiratory viral infection (RVI) following human lung transplantation (LTx) increases the risk for chronic rejection. We demonstrated that lung transplant recipients (LTxR) with acute and…
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