ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion

    Y. Boteon,1,2 R. Laing,1,2 A. Schlegel,2 J. Attard,1,2 L. Wallace,1 A. Smith,2 T. Perera,2 J. Isaac,2 D. Mirza,2 S. Afford,1 H. Mergental.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
  • 2018 American Transplant Congress

    Comparison of Outcomes in African-American and White Primary Kidney Transplant Recipients: A Matched-Pair Analysis

    F. Tedla, A. Brar, D. John, N. Sumrani, R. Gruessner, A. Gruessner, M. Salifu.

    SUNY Downstate Medical Center, Brooklyn, NY.

    Background: Racial differences in clinical and sociodemographic characteristics have been well recognized. This study aims to assess outcomes in African-American (AA) and white primary deceased…
  • 2018 American Transplant Congress

    Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation

    B. Ho,1 S. Montag,1,2 H. Bhagat,3 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Inc., Northbrook.

    Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
  • 2018 American Transplant Congress

    Characteristics and Outcomes of Kidney Transplant Recipients with More Than 25 Years of a Functioning Graft

    S. Parajuli, D. Mandelbrot, F. Aziz, N. Garg, M. Mohamed, B. Muth, B. Astor, A. Djamali.

    University of Wisconsin, Madison.

    Background: There is limited information on clinical characteristics and outcomes of kidney transplant recipients (KTRs) with more than 25 years of graft survival.Methods: We addressed…
  • 2018 American Transplant Congress

    Pump Resistive Index Values and Not Preimplantation Kidney Biopsy Predict Kidney Allograft Survival

    J. Liu,1 A. Blumfield,1 M. Trivedi,1 N. Mishra,1 O. Mohammed,1,2 J. Lin,3 M. Ajaimy,1,2 J. Graham,1,2 J. Rocca,1,2 E. Akalin,1,2 S. Greenstein.1,2

    1Albert Einstein College of Medicine, Bronx, NY; 2Department of Surgery, Montefiore Medical Center, Bronx, NY; 3Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.

    AimTo investigate the relationship between histological findings of preimplantation kidney biopsies and pump resistive index (RI) values during machine preservation and subsequent allograft survival.MethodsWe retrospectively…
  • 2018 American Transplant Congress

    Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation

    S. Rayhill, J. Haldorson.

    U Washington, Seattly.

    There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…
  • 2018 American Transplant Congress

    Safety and Efficacy of Sofosbuvir-Based Direct-Acting Antiviral Agents in Kidney Transplant Recipients with HCV: A Systematic Review and Meta-Analysis

    X. Wang,1 P. Tan,1 T. Xiang,2 Y. Qiu,1 T. Song,1 T. Lin.1

    1Department of Urology/Institute of Urology/Organ Transplantation Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China; 2West China School of Clinical Medicine, Sichuan University, Chengdu, Sichuan Province, China.

    Background: Outcome data on sofosbuvir (SOF)-based therapy in patients with kidney transplantation (KTx) with hepatitis C virus infection are limited with individual studies having a…
  • 2018 American Transplant Congress

    Ten Years of Low-Dose Valganciclovir; Evaluating the Incidence and Risk Factors of CMV in Kidney Transplant Recipients

    S. El Hajj, J. Azzi, M. Kim, S. Gabardi.

    Pharmacy, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Kidney Transplant, Brigham and Women's Hospital, Boston; Kidney Transplant, Brigham and Women's Hospital, Boston.

    Introduction: Cytomegalovirus (CMV) remains one the most clinically relevant and frequent post-transplant infections. Despite the availability of effective antiviral drugs, CMV continues to be of…
  • 2018 American Transplant Congress

    Clinical Significance of Isolated v-Lesions in Kidney Transplantation

    A. Georgalis,1 C. Wehmeier,1 P. Hirt-Minkowski,1 G. Hönger,1 H. Hopfer,2 J. Steiger,1 S. Schaub,1 P. Amico.1

    1Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland; 2Institute for Pathology, University Hospital Basel, Basel, Switzerland.

    Background: Arteritis without significant tubulo-interstitial inflammation (v1-3, but i≤1 and t≤1) is referred by the 10th Banff conference as 'isolated v-lesions'. The clinical significance of…
  • 2018 American Transplant Congress

    New SLK Allocation Policy May Impact Transplant Outcomes in Women

    G. Cullaro,1 R. Hirose,2 J. Lai.1

    1Medicine, University of California, San Francisco, San Francisco, CA; 2Transplant Surgery, University of California, San Francisco, San Francisco, CA.

    Background: Previous SLK allocation was based on serum creatinine(Cr), a metric that disadvantaged women(W) relative to men(M). A SLK policy change utilizes eGFR, which accounts…
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