ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Outcomes of Kidney Transplant Recipients with Early Allograft Inflammation: A Prospective Study

    R. Mehta, S. Tandukar, P. Sood, C. Puttarajappa, C. Wu, N. Shah, A. Tevar, S. Hariharan.

    University of Pittsburgh Medical Center, Pittsburgh.

    The impact of early allograft inflammation is unclear. We prospectively studied changes in renal function and histology in a cohort of patients who received a…
  • 2018 American Transplant Congress

    Liver Transplantation with or without Left Renal Vein Ligation: Comparative Study of 105 Cases

    M. Perosa,1 H. Noujaim,1 J. Branez,1 L. Mota,1 B. Zeballos,1 R. Santos,1 A. Watanabe,2 G. Ferreira,2 A. Moraes,2 A. Silvestre,3 G. Martinho,4 N. Siqueira,5 T. Genzini.1

    1Abdominal Organ Transplantation, Leforte Hospital, Sao Paulo, Brazil; 2ICDF Hospital, Brasilia, Brazil; 3Medical School, Sao Camilo, Sao Paulo, Brazil; 4Medical School, Santa Casa, Sao Paulo, Brazil; 5Hospital das Clínicas, Rio Branco, Acre, Brazil.

    The presence of large spontaneous splenorenal shunts (SSRS) is a risk factor for low portal flow and graft dysfunction after liver transplantation (LT). Left renal…
  • 2018 American Transplant Congress

    The Learning Curve in 100 Consecutive Live Liver Donors Undergoing Pure Laparoscopic Right Hepatectomy

    K. Suh, S. Hong, K. Yoon, J-.M. Lee, J-.H. Cho, N-.J. Yi, K. Lee.

    Surgery, Seoul National University College of Medicine, Seoul, Korea.

    Introduction: Laparoscopic donor hepatectomy is evolving as a new option in live liver donor surgery considering donor's cosmetic and functional demand. However, laparoscopic donor major…
  • 2018 American Transplant Congress

    Advancement in Perioperative Outcomes of Living Donors in Pure Laparoscopic Right Hepatectomy

    Y. Choi, H. Han, Y. Yoon, J. Cho, B. Lee.

    Department of Surgery, Seoul National University, College of Medicine, Seongnam, Republic of Korea.

    Background In the early period, laparoscopic liver resection was applied in limited cases, but now the number of cases and its application is rapidly increasing.…
  • 2018 American Transplant Congress

    Mitochondrial Quality Control through PGC-1α in Syngenic Mouse Heart Transplant

    A. Cherry,1 K. Porter,1 H. Suliman,1 J. Wang,2 M. Mulvihill,2 A. Kirk.2

    1Anesthesiology, Duke University, Durham, NC; 2Surgery, Duke University, Durham, NC.

    Intro: Impaired mitochondrial function plays a role in graft dysfunction after transplant, and recovery is facilitated by mitochondrial quality control (MQC). Two key elements of…
  • 2018 American Transplant Congress

    Noninvasive Quantization of Intra-Renal Allograft C4d Deposition with Targeted Ultrasound Imaging

    T. Liao,1 Y. Zhang,1 J. Ren,2 H. Zheng,1 H. Zhang,2 X. Liu,1 T. Yin,2 Q. Sun.1

    1Organ Transplantation Research Institute, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; 2Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Antibody-mediated rejection (AMR) has emerged as the major cause of renal allograft dysfunction. C4d, a specific marker of AMR diagnosis, was strongly recommended for routine…
  • 2018 American Transplant Congress

    Building a Third-Party VST Bank from Scratch- The Cincinnati Experience

    A. S. Nelson,1 D. Heyenbruch,2 X. Zhu,3 S. M. Davies,1 C. Lutzko,3 C. Bollard,4 P. Hanley,4 T. Leemhuis,2 L. Danziger-Isakov,5 M. S. Grimley.1

    1Bone Marrow Transplant & Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 2Hoxworth Blood Center, Univeristy of Cincinnati, Cincinnati, OH; 3Experimental Hematology & Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 4Proram for Cell Enhancement and Technologies for Immunotherapy, Children's National Health System, Washington, DC; 5Depatment of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    BackgroundViral infections remain a challenge to treat and significantly contribute to morbidity and mortality. Virus specific T cells (VSTs) have shown clinical efficacy, with minimal…
  • 2018 American Transplant Congress

    Precision (re)Phenotyping of Histologically Stable Kidney Transplants

    D. Rychkov,1 T. Sigdel,2 M. Sirota,1 M. Sarwal.2

    1Institute for Computational Health Sciences, UCSF, San Francisco, CA; 2Department of Surgery, UCSF, San Francisco, CA.

    Background: Acute Rejection (AR) is the main cause of the renal failure within one year after transplantation (tx). Its earlier diagnosis is crucial for a…
  • 2018 American Transplant Congress

    Carfilzomib and Belatacept Reduces DSA and Prolongs Survival in a Highly Sensitized Rhesus Model of Kidney Transplantation

    B. Ezekian, J. Kwun, P. Schroder, M. Manook, J. Yoon, M. Mulvihill, K. Freischlag, J. Cochran, K. Kroning, J. Yi, S. Knechtle.

    Duke Transplant Center, Duke University Medical Center, Durham, NC.

    Purpose:Sensitized kidney transplant (KT) recipients have poor access to transplantation and inferior outcomes when transplanted. Conventional methods of desensitization remove donor specific antibody (DSA) temporarily,…
  • 2018 American Transplant Congress

    Identification of Exosomal Isletokines Released by Pancreatic Islets in Response to Inflammatory Stress

    P. Saravanan,1 G. Yoshimatsu,1 R. Bhattacharjee,1 C. Chang,1 C. Darden,1 B. Naziruddin,2 M. Lawrence.1

    1Islet Cell Lab, Baylor Scott & White Research Institute, Dallas, TX; 2Transplantation, Baylor Simmons Transplant Institute, Dallas, TX.

    Purpose: To identify isletokines released by exosomes from human islets that have been exposed to hypoxic or inflammatory conditions and define stress signaling pathways that…
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