Am J Transplant, Volume 18, Suppl 3 Archives - Page 52 of 211 - ATC Abstracts

2018 American Transplant Congress
Comparison of Temperatures for Optimal Preservation of Donor Kidneys during Oxygenated Pulsatile Perfusion
R. Bhattacharjee,¹ M. Richard-Mohamed,² A. Ruthirakanthan,³ R. Mayer,² S. Luke,³ H. Sharma,² M. TunAbraham,² B. Alharbi,² A. Haig,² P. Luke.^1,2,3
¹Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Western University, Canada, London, ON, Canada.
Background. The current methods of preserving DCD renal allografts in either static cold solution or hypothermic pulsatile perfusion are unable to adequately protect the kidney…
2018 American Transplant Congress
The Superiority of Plasma Enriched Perfusate for Assessment of Donor Kidneys in an Ex-Vivo Normothermic Perfusion (EVNP) Setting
J. Palma, I. Palma, Y. Smolin, A. Perry, J. Sageshima, R. Perez.
Surgery, Transplant Division, UC Davis Health System, Sacramento, CA.
EVNP has been used to assess and repair marginal organs prior to transplantation but the optimal perfusate composition is unknown. We hypothesize that EVNP with…
2018 American Transplant Congress
Consistency of DCD Procurement Procedures across Organ Procurement Organizations – Preliminary Findings
G. Mitro,¹ A. Ortiz,² R. Warnock,³ P. Wiederhold,³ K. Jiles,³ J. Ortiz.¹
¹University of Toledo College of Medicine, Toledo, OH; ²University of California Los Angeles, Los Angeles; ³Life Connection of Ohio, Toledo, OH.
Intro: Variation among procedures across Organ Procurement Organizations (OPOs) may account for discrepancies in outcomes associated with the use of deceased after cardiac death (DCD).…
2018 American Transplant Congress
Cognitive Impairment and Graft Loss in Kidney Transplant Recipients
A. Thomas,¹ J. Ruck,¹ A. Shaffer,¹ C. Haugen,¹ H. Ying,¹ F. Warsame,¹ N. Chu,¹ M. Carlson,¹ A. Gross,¹ S. Norman,² D. Segev,¹ M. McAdams-DeMarco.¹
¹JHU, Baltimore; ²University of Michigan, Ann Arbor.
Cognitive impairment is common in end-stage renal disease patients and impedes adherence to complex treatment regimens. Given the complexities of post-transplant immunosuppression, we hypothesized that…
2018 American Transplant Congress
Urinary Sulfate Excretion and Late Graft Failure in Renal Transplant Recipients
M. Said,¹ A. Post,¹ I. Minovic,¹ M. van Londen,¹ H. van Goor,² D. Postmus,³ M. Heiner-Fokkema,⁴ E. van den Berg,¹ A. Pasch,⁵ G. Navis,¹ S. Bakker.¹
¹Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands; ²Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands; ³Department of Epidemiology, University of Groningen, Groningen, Netherlands; ⁴Department of Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands; ⁵Department of Biomedical Research, University of Bern, Bern, Switzerland.
BackgroundHydrogen sulfide (H2S), produced from the metabolism of dietary sulfur-containing amino acids, is allegedly a potential renoprotective compound. High 24h urinary excretion of pathway intermediate…
2018 American Transplant Congress
Histogenomics: Molecular Profiling of Kidney Biopsies Predict Delayed Graft Function
P. Rao,¹ D. Deo,¹ B. Fyfe-Kirschner,² R. Siderits.²
¹NJ Sharing Network, New Providence, NJ; ²Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
IntroductionHistologic assessments of donor renal biopsies for percentage global glomerulosclerosis, interstitial fibrosis and arterial sclerosis can predict renal graft failure post-transplant.The morphologic evaluation of renal…
2018 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85 in Older Recipients
A. Nickkholgh,¹ A. Agarwal,¹ A. Nishio Lucar,² K. Brayman,¹ A. Doyle,² J. Oberholzer.¹
¹Dept. of Surgery, University of Virginia Health System, Charlottesville, VA; ²Dept. of Internal Medicine, University of Virginia Health System, Charlottesville, VA.
Background: High kidney donor profile index (KDPI >85%) organs can grant earlier access to transplantation particularly for those who are frail, have limited waiting time…
2018 American Transplant Congress
Pre-Existing Allograft Diabetic Nephropathy from Diabetic Donor is Reversible after Kidney Transplantation in Non-Diabetic Recipient
K. Hotta,¹ D. Iwami,¹ H. Harada,² Y. Fukasawa,² H. Okada,¹ H. Higuchi,¹ T. Hirose,² N. Fukuzawa,² N. Shinohara.¹
¹Hokkaido University Hospital, Sapporo, Japan; ²Sapporo City General Hospital, Sapporo, Japan.
【Introduction】The shortage of kidney donor has limited the treatment of patients with end-stage kidney disease. To use diabetic donor with normal renal function is would…
2018 American Transplant Congress
Treatment of HCV Infection in Renal Transplant Recipients
M. Rial, L. Tana, C. Alonso, H. Curcio, E. Chulluyan, D. Casadei.
Renal Transplant Unit, Instituto de Nefrologia Nephrology, Buenos Aires, Argentina.
HCV infection is associated to chronic hepatitis, cirrhosis, hepatic carcinoma and increased incidence of diabetes. Combination of new antiviral drugs have demonstrated utility in liver…
2018 American Transplant Congress
BK Nephropathy in Non-Kidney Transplant Patients, a Case Series and Systematic Review of the Literature
A. Shah,¹ V. Kumar,² B. Laskin,^2,3 D. Sawinski,^1,2 J. Hogan.^1,2
¹Division of Nephrology, Hospital of the University of Pennsylvania, Philadelphia; ²Perelman School of Medicine, Philadelphia; ³Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia.
Background: BK virus is highly seroprevalent but clinical disease typically occurs only in immunocompromised persons, most notably leading to significant morbidity in patients with kidney…