Am J Transplant, Volume 18, Suppl 3 Archives - Page 52 of 211 - ATC Abstracts

2018 American Transplant Congress
Differences in Preservation Solution Formulas and Its Effects on Early Graft Function
J. Brooks, P. Wiederhold, K. Jiles, A. Chiodo Ortiz, M. Dewey, M. Bailey, N. Koizumi, E. Rady, J. Ortiz.
University of Toledo Medical Center, Toledo, OH; University of California-Los Angeles, Los Angeles, CA; Life Connection of Ohio, Maumee, OH; George Mason University, Fairfax, VA.
Introduction: Machine perfusion has proven benefits and is common practice among transplant centers. However, the formulas of preservation solutions vary between organ procurement organizations (OPOs).…
2018 American Transplant Congress
Viability Outcomes for Donor Livers Discarded Due to Steatosis Following Extra-Corporeal Machine Perfusion of the Liver
Y. Boteon,^1,2 R. Laing,^1,2 D. Neil,² A. Schlegel,² J. Attard,^1,2 G. Reynold,¹ P. Muiesan,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Steatosis is the main reason for discarding donor livers worldwide. Ex-vivo machine perfusion offers superior preservation for marginal organs and permits viability testing during…
2018 American Transplant Congress
Early Utilization of Telehealth in Kidney Transplantation
T. Young, D. Hricik, E. Sanchez, N. Sarabu.
Transplant Institute, University Hospitals of Cleveland, Cleveland, OH.
Introduction: Telehealth is an emerging strategy to improve outcomes and decrease emergency department visits and readmissions. Utility of telehealth in kidney transplantation hasn't been much…
2018 American Transplant Congress
Donor Specific Antibodies and Clinical Outcomes in Kidney Transplant Recipients
S. Wan,^1,2 S. Chadban,^1,2 K. Wyburn.^1,2
¹Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²Sydney Medical School, University of Sydney, Sydney, Australia.
BACKGROUND: Donor specific antibodies (DSA) have been implicated in the development of acute rejection (AR) and graft dysfunction in kidney transplant recipients (KTx). However, limited…
2018 American Transplant Congress
Multiparametric MRI for Assessment of Renal Transplant Fibrosis: A Pilot
M. Menon, O. Bane, S. Lewis, R. Khaim, S. Florman, P. Kennedy, S. Hectors, V. Delaney, F. Salem, B. Taouli.
Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, New York, NY.
Fibrosis in renal allografts confers risk of progression to allograft loss. The gold standard for evaluating renal fibrosis remains allograft biopsy, which is invasive, prone…
2018 American Transplant Congress
Outcomes of Very Old Kidney Recipients of Grafts from Very Old Donors
H. Trujillo, A. García, T. Cavero, B. Redondo, C. Moliz, T. Bada, E. González, M. Praga, A. Andrés.
Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
Aims: Describe the outcomes of very old kidney recipients of grafts from very old donors. Identify pretransplant clinical factors associated with graft and recipient survival.Methods:…
2018 American Transplant Congress
APOL1 Long-Term Kidney Transplantation Outcomes Network (APOLLO)
G. Guerra,¹ E. Poggio,² M. Ortigosa-Goggins,¹ M. Doshi,³ B. Freedman,⁴ D. Reboussin,⁴ P. Kimmel,⁵ APOLLO Investigators.
¹Miami Transplant Institute, Miami, FL; ²Cleveland Clinic, Cleveland, OH; ³University of Michigan, Ann Arbor, MI; ⁴Wake Forest School of Medicine, Winston-Salem, NC; ⁵NIDDK, Bethesda, MD.
Two renal-risk variants in the apolipoprotein L1 gene (APOL1) are powerfully associated with a spectrum of non-diabetic chronic kidney diseases in populations with recent African…
2018 American Transplant Congress
Multi-Drug Resistant Urinary Tract Infections Following Renal Transplant: Risk Factors and Patient Outcomes
D. Hooker,¹ K. Gutierrez,² K. Foster,¹ A. Dodson.²
¹Samford University McWhorter School of Pharmacy, Birmingham, AL; ²Comprehensive Transplant Institute, UAB Hospital, Birmingham, AL.
Background: Urinary tract infections (UTIs) are the most common infection after kidney transplant (KTx) resulting in significant morbidity and mortality. The reported incidence of UTIs…
2018 American Transplant Congress
Klotho, HMGB-1 and Kynurenine as Marker for Injury and Function in Renal Transplantation
M. Stangl,¹ D. Abendroth.²
¹Transplant Center Munich, Klinikum Großhadern, LMU Munich, Munich, Germany; ²Surgery, University of Ulm, Ulm, Germany.
Brain death is associated with immune activation and tissue injuries, counter regulated by activation of the tryptophan pathway producing kynurenine (Kyn). High mobility group box…
2018 American Transplant Congress
Delayed Achievement of Therapeutic Tacrolimus Levels after Renal Transplantation is Not Associated with Increased Incidence of Early Acute Rejection: Single-Center Results
R. Marshall, J. Brandenberger, A. Cantafio, J. Halldorson, R. Bakthavatsalam, A. Dick, S. Rayhill, J. Reyes, J. Perkins.
Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA.
Induction therapy followed by maintenance with a calcineurin inhibitor aims to minimize the incidence of early rejection and optimize the potential for allograft function. However…