ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    The Net State of Immunosuppression in Septuagenarian Liver Transplant Recipients: Balancing Rejection and Infection Risks

    J. Casale,1 J. Clark,1 B. Ravichandran,1 J. LaMattina.2

    1Pharmacy, University of Maryland Medical Center, Baltimore; 2University of Maryland School of Medicine, Baltimore.

    Purpose: Careful patient selection and perioperative management have allowed for successful liver transplantation in elderly patients. Elderly patients may be more susceptible to the infectious…
  • 2018 American Transplant Congress

    Clinical Impact of Antecedent Bariatric Surgery on Liver Transplant Outcomes: A Retrospective Matched Case-Control Study

    O. Serrano,1 K. Peterson,1 D. Vock,2 D. Berglund,1 R. Kandaswamy,1 J. Lake,3 T. Pruett,1 S. Chinnakotla.1

    1Surgery, University of Minnesota, Minneapolis, MN; 2Biostatistics, University of Minnesota, Minneapolis, MN; 3Medicine, University of Minnesota, Minneapolis, MN.

    OBJECTIVE: Bariatric surgery (BS) is associated with significant malabsorption and nutritional deficiencies, which can have profound consequences on the liver transplant (LT) patient. The magnitude…
  • 2018 American Transplant Congress

    Outcomes of Liver Transplant in Sequential Eras in Patients with Polycystic Liver Disease at Various Stages of Disease

    C. Desai,1 J. Shurney,1 P. Serrano Rodriguez,1 A. Barritt,1 D. Gerber,1 A. Gruessner.2

    1University of North Carolina, Chapel Hill, NC; 2SUNY Downstate Medical Center, Brooklyn, NY.

    Patients with polycystic liver disease (PLD) receive liver transplants at various time points in their disease process. Some patients receive liver transplant alone (L), some…
  • 2018 American Transplant Congress

    Disparate Risk Factors for Early and Late Death Impact Survival after Lung Transplant

    C. Lehr, E. Blackstone, K. McCurry, L. Thuita, W. Tsuang, M. Valapour.

    Cleveland Clinic, Cleveland, OH.

    Purpose: After implementation of the lung allocation score, there has been improvement in one- and three-year survival but not in five-year survival after lung transplant…
  • 2018 American Transplant Congress

    Aquaporin 4 Blockade Alters T Cell Trafficking through a Novel Mechanism of S1PR1 Regulation

    M. Nicosia,1 R. Fan,1 S. Miyairi,1 A. Beavers,1 G. Farr,2 P. McGuirk,2 M. Pelletier,2 A. Valujskikh.1

    1Immunology, Cleveland Clinic, Cleveland, OH; 2Aeromics LLC, Cleveland, OH.

    The ubiquitous water channels aquaporins mediate a variety of immune functions. We previously demonstrated that aquaporin 4 (AQP4) is expressed by CD4 and CD8 T…
  • 2018 American Transplant Congress

    An Enhanced Educational Program for Kidney Transplant Candidates and Their Supports: Knowledge Gained but Room for Improvement

    E. Clifton, A. Eshelman, D. Kim, A. Patel, P. Williams, D. Nicholson, K. Hogan, E. Rubinstein, D. Ramirez, N. Sadik, M. Jesse.

    Henry Ford Health System, Detroit.

    Given the complexities of transplantation, success relies on both medical and lifestyle management. Patients and their support systems require extensive education on the requirements of…
  • 2018 American Transplant Congress

    Transmission of Rabies through Solid Organ Transplant: A Big Issue in China

    J. Zhang, J. Lin, Y. Tian, L. Ma, W. Sun, L. Zhang, Y. Zhu, W. Qiu, L. Zhang.

    Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

    Purpose To summarize and analyze the clinical characteristic, prophylaxis and treatment of rabies transmitted through solid organ transplant. Methods Four recipients and their donors diagnosed…
  • 2018 American Transplant Congress

    Colistin (COL) in Solid Organ Transplant Recipients (SOTR): Friend or Foe?

    K. Neyra, C. Huauya Leuyacc, C. Kovacs, V. Athans, E. Cober.

    Cleveland Clinic, Cleveland, OH.

    Background: Data on COL use in SOTR are lacking. In other populations, high dose (HD) COL (>4.4mg/kg/day) has been associated with clinical and microbiologic cure…
  • 2018 American Transplant Congress

    Prevalence and Infection-Related Outcomes Associated with Transplant Tourism

    J. Slomovic, S. Humar, D. Kumar, A. Humar.

    Transplant Infectious Diseases, Toronto General Hospital, Toronto, ON, Canada.

    Background:Patients who receive organ transplants via transplant tourism may have a greater risk of complications. We sought to describe the infectious risks associated with this…
  • 2018 American Transplant Congress

    TACI-Ig as a Desensitization Agent in a Rat Model of Antibody Mediated Rejection

    N. Wilson,1 B. Verhoven,2 B. Boldt,2 N. Bath,2 X. Ding,1 R. Redfield III.2

    1Medicine/Nephrology, University of Wisconsin, Madison, WI; 2Surgery/Transplant, University of Wisconsin, Madison, WI.

    We examined the effect of APRIL/BLyS blockade on B cell lineages & donor specific antibody (DSA) in preclinical rodent model as a novel desensitization strategy.…
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