ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Redo Kidney Transplant in FSGS

    J. Verbesey, A. Javaid, S. Yi, G. Vranic, A. Gilbert, P. Abrams, S. Ghasemian, J. Moore, B. Thomas, M. Cooper, B. Javaid.

    Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, Washington, DC.

    Objective: Analyze risk of graft failure due to recurrent FSGS in patients with prior failed kidney transplants under consideration for a subsequent transplant.Results: We identified…
  • 2018 American Transplant Congress

    Cannabis Dependence or Abuse before and after Kidney Transplantation: Implications for Post-Transplant Outcomes

    K. Lentine,1 T. Alhamad,2 N. Lam,3 A. Naik,4 F. Koraishy,1 H. Randall,1 D. Segev,5 V. Dharnidharka,2 D. Brennan,5 B. Kasiske,6 R. Ouseph,1 M. Schnitzler.1

    1Saint Louis Univ, St. Louis; 2Washington Univ, St. Louis; 3Univ Alberta, Edmonton, Canada; 4Univ Michigan, Ann Arbor; 5Johns Hopkins, Baltimore; 6Hennepin County Med Ctr, Minneapolis.

    Currently, transplant centers vary in screening practices for marijuana use and requirements for abstinence before kidney transplantationWe examined billing claims and linked SRTR data for…
  • 2018 American Transplant Congress

    Metformin Use after Kidney Transplantation: A Safe Option in Carefully Selected Patients

    F. Koraishy,1 L. Vest,1 Z. Zhang,1 M. Schnitzler,1 V. Dharnidharka,2 D. Axelrod,3 R. Ouseph,1 A. Naik,4 N. Lam,5 H. Randall,1 T. Alhamad,2 D. Segev,3 D. Brennan,3 B. Kasiske,6 G. Hess,7 K. Lentine.

    1Saint Louis Univ, St. Louis; 2Washington Univ, St. Louis; 3Lahey Clinic, Burlington; 4Univ Michigan, Ann Arbor; 5Univ Alberta, Edmonton; 6Johns Hopkins, Baltimore; 7Hennepin County, Minneapolis; 8Symphony Health, Conshohocken.

    Recent guidelines support metformin as a therapeutic option in diabetic patients with mild to moderate renal insufficiency. The frequency and outcomes of metformin use in…
  • 2018 American Transplant Congress

    Development and Validation of a Socioeconomic Kidney Transplant Derailers Index (KTDI)

    J. Peipert,1,2 J. Beaumont,2 M. Robbins,3 A. Paiva,3 C. Anderson,1 A. Waterman.1,2

    1UCLA, Los Angeles, CA; 2Terasaki Research Institute, Los Angeles, CA; 3Univ. of Rhode Island, Kingston, RI.

    Transplant evaluation requires an assessment of socioeconomic challenges patients face that may derail them from obtaining a kidney transplant (KT). We developed and validated a…
  • 2018 American Transplant Congress

    High Frequency of HLA-DQ De Novo Donor Specific Antibodies is Independent of the Number of Mismatches in Heart Transplant

    X. Zhang,1 E. Kransdorf,2 J. Patel,2 J. Kobashigawa.2

    1HLA and Immunogenetics Laboratory/ Comprehensive Transplant Center, Cedars-Sinai Health Systems, Los Angeles, CA; 2Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA.

    Aim: Development of de novo donor specific antibodies (DSA) after heart transplant is associated with an increased risk of allograft failure. The aim of this…
  • 2018 American Transplant Congress

    T-Cell Depletion Does Not Increase the Risk of CMV Infection in Donor-Positive, Recipient-Negative Kidney Transplants Due to the Absence of Preformed CMV-Specific Cell-Mediated Immunity

    M. Jarque,1 H. Kaminski,2 L. Couzi,2 E. Crespo,1 J. Déchanet-Merville,3 S. Luque,1 N. Montero,4 M. Pascual,5 O. Manuel,5,6 P. Merville,2 O. Bestard.1,4

    1Nephrology Lab, IDIBELL, Barcelona, Spain; 2Nephrology Dep, Hôpital Pellegrin, Bordeaux, France; 3National Center of Scientific Research, Bordeaux, France; 4Nephrology Dep, Bellvitge Hospital, Barcelona, Spain; 5Transplantation Center, Lausanne Hospital, Lausanne, Switzerland; 6Infectious Diseases Dep, Lausanne Hospital, Lausanne, Switzerland.

    Kidney transplants (KT) with R-/D+ CMV serostatus receiving T-cell depletion induction are considered as the highest risk population for CMV infection and long-lasting prophylaxis therapy…
  • 2018 American Transplant Congress

    Bortezomib in Late Antibody-Mediated Kidney Transplant Rejection – A Double-Blind Randomized Placebo-Controlled Trial (BORTEJECT Study)

    F. Eskandary,1 H. Regele,2 G. Bond,1 N. Kozakowski,2 M. Wahrmann,1 L. Hidalgo,3 H. Haslacher,4 C. Kaltenecker,1 M-.B. Aretin,5 R. Oberbauer,1 J. Reeve,6 P. Halloran,6 G. Böhmig.1

    1Nephrology and Dialysis, Medical University Vienna, Viena, Austria; 2Institute of Clinical Pathology, Medical University Vienna, Vienna, Austria; 3Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; 4Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria; 5Pharmacy Department, General Hospital Vienna, AKH, Vienna, Austria; 6Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada.

    Background. Antibody-mediated rejection (ABMR) is a leading cause of long-term kidney transplant loss. Optimal treatment of late ABMR is unclear, and our current knowledge is…
  • 2018 American Transplant Congress

    Trends, Patterns, and Recipient Outcomes of Kidney Transplants from Older (>60) Living Donors. A UNOS Database Analysis

    A. Riaz, O. Adebiyi, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.

    Indiana University, Indianapolis.

    Backgroud: The selection of older donors (>60 years) has become more common. Our aim was to analyze the recent national trends of such donors and…
  • 2018 American Transplant Congress

    Comparison of BMI, Waist Circumference and Waist-to-Height Ratio for Identification of Cardiovascular Risk in Pediatric Kidney Transplant Recipients

    K. Sgambat, S. Clauss, A. Moudgil.

    Children's National, Washington DC.

    Background: Children with kidney disease have altered body composition and short stature that may not be accurately assessed by standard methods. The measure of obesity…
  • 2018 American Transplant Congress

    Making Sense of Hepatitis B Reactivation Risk in Anti-HBc Antibody (Ab) Positive Liver Transplant Recipients

    S. Leistman,1 J. Melaragno,1 M. Dokus,2 B. Al-Judaibi,2 T. Babu.3

    1Department of Pharmacy, University of Rochester Medical Center, Rochester, NY; 2Division of Transplantation, University of Rochester Medical Center, Rochester, NY; 3Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY.

    Background: Limited data exists regarding the rates of reactivation of hepatitis B virus (HBV) in anti-HBc Ab positive orthotopic liver transplant (OLT) recipients. Protocols vary…
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