Am J Transplant, Volume 18, Suppl 3 Archives - Page 39 of 211 - ATC Abstracts

2018 American Transplant Congress
New Onset Diabetes after Kidney Transplant: Comparisons of Risks Associated with Various Steroid-Containing Calcineurin Inhibitor and Sirolimus Regimens
A. Santos, Jr.,¹ M. Casey,¹ K. Alquadan,¹ X. Wen,² C. Chen,³ A. Gutierrez-Mena,¹ K. Womer.¹
¹College of Medicine, Univ. of Florida, Gainesville, FL; ²College of Pharmacy, Univ. of Rhode Island, Kingston, RI; ³College of Pharmacy, Univ. of Florida, Gainesville, FL.
INTRODUCTION: We aimed to examine the risk of new onset diabetes after transplant (NODAT) associated with the following maintenance immunosuppression regimens in kidney transplant recipients…
2018 American Transplant Congress
Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation
E. Hsu,² J. Ge,¹ J. Bucuvalas,³ J. Lai.¹
¹UC-San Francisco, San Francisco, CA; ²Seattle Children's Hospital, Seattle, WA; ³Cincinnati Children's Hospital, Cincinnati, OH; ⁴University of California San Francisco, San Francisco, CA.
Background:The current liver allocation algorithm for livers from deceased pediatric (<18y; “pedi“) donors prioritizes adults listed locally/regionally over children listed nationally. We sought to understand…
2018 American Transplant Congress
Obesity is Not Associated with Worse Outcomes for Type 2 Diabetic Simultaneous Pancreas-Kidney (SPK) Transplant Recipients
R. Forbes, S. Niederhaus, A. Fox, J. Fridell, P. Abrams, O. Olaitan, F. Kandeel, R. Urban, M. Curry, J. Odorico.
Pancreas T2D Subcommittee, UNOS, Richmond.
BACKGROUND: Per current SPK allocation policy, Type 2 Diabetic (T2D) candidate waiting time is contingent on a body mass index (BMI, kg/m2) less than or…
2018 American Transplant Congress
Legal Status, Criminal History, and Substance Use in Listing Decisions
G. Lee, A. Wall, J. Maldonado, D. Magnus.
School of Medicine, Stanford University, Stanford, CA; Stanford University Medical Center, Stanford, CA.
Background: Psychosocial criteria constitute absolute and relative contraindications to listing, which can bar patients from access to organ transplantation at a program. Refusing to list…
2018 American Transplant Congress
Single-Cell Analysis of Graft Infiltrating T-Cells in Cardiac Allograft Vasculopathy
M. Habal, A. Myung, H. Yan, S. Rao, S. Lin, P. Colombo, C. Marboe, S. Restaino, A. Han, M. Farr, E. Zorn.
Medicine, Columbia University Medical Center, New York, NY.
Background: Cardiac allograft vasculopathy (CAV) remains a leading cause of death after heart transplant.T-cells are thought to play a central role, yet the mechanism by…
2018 American Transplant Congress
Unraveling the Neuroimmunological Pathways Surrounding Brain Death: Systematic Study of Clinically Relevant Serum Biomarker Changes during Donor Management from Admission to Procurement
K. Bera, M. LoFaro, H. Huang, S. Maslau, R. Ploeg.
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Donation after brain death (BD) remains an important source of transplanted organs worldwide and it has been shown that BD causes a hostile environment with…
2018 American Transplant Congress
Tacrolimus Metabolism in Subjects with Potentially Absent CYP3A Activity
A. Scheibner,¹ R. Remmel,² D. Schladt,³ W. Oetting,¹ W. Guan,⁴ B. Wu,⁴ C. Door,⁵ A. Israni,⁵ P. Jacobson.¹
¹Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN; ²Medicinal Chemistry, University of Minnesota, Minneapolis, MN; ³Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; ⁴Biostatistics, University of Minnesota, Minneapolis, MN; ⁵Department of Medicine, Hennepin County Medical Center, Minneapolis, MN.
Purpose: Tacrolimus (TAC) is a well-known cytochrome P450 (CYP) 3A4 and 3A5 substrate. Common single nucleotide polymorphisms (SNPs) in these genes are significantly related to…
2018 American Transplant Congress
Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy
M. Banas,¹ S. Neumann,² P. Pagel,² D. Chittka,¹ V. Pfahlert,² B. Banas.¹
¹Department of Nephrology, University Hospital Regensburg, Regensburg, Germany; ²numares HEALTH, Regensburg, Germany.
Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…
2018 American Transplant Congress
Intentional Transplantation of Hepatitis C Positive Livers into Hepatitis Negative Recipients- Report of the First Case-Series in the World
P. Martins, B. Movahedi, A. Ahearn, A. Bozorgzadeh.
Dept. of Surgery, Univ of Massachusetts, Worcester, MA.
Background: The current disparity between supply and demand of liver grafts has dramatically increased the waiting time and mortality on the waiting list. The recent…
2018 American Transplant Congress
A Novel Approach to Preserve Pancreatic Islet Grafts in Extrahepatic Space for Reversal of Diabetes Using Parathyroid Gland Co-Transplantation
C. Ward, G. Faleo, G. Nair, Q. Duh, M. Hebrok, W. Chang, P. Stock, Q. Tang.
UCSF, San Francisco, CA.
Intro: Islet transplantation can cure type 1 diabetes; however, multiple donors are needed due to extensive perioperative loss of islets away from their native blood…