2018 American Transplant Congress
Unraveling the Neuroimmunological Pathways Surrounding Brain Death: Systematic Study of Clinically Relevant Serum Biomarker Changes during Donor Management from Admission to Procurement
Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Donation after brain death (BD) remains an important source of transplanted organs worldwide and it has been shown that BD causes a hostile environment with…2018 American Transplant Congress
Tacrolimus Metabolism in Subjects with Potentially Absent CYP3A Activity
Purpose: Tacrolimus (TAC) is a well-known cytochrome P450 (CYP) 3A4 and 3A5 substrate. Common single nucleotide polymorphisms (SNPs) in these genes are significantly related to…2018 American Transplant Congress
Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy
Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…2018 American Transplant Congress
Intentional Transplantation of Hepatitis C Positive Livers into Hepatitis Negative Recipients- Report of the First Case-Series in the World
Dept. of Surgery, Univ of Massachusetts, Worcester, MA.
Background: The current disparity between supply and demand of liver grafts has dramatically increased the waiting time and mortality on the waiting list. The recent…2018 American Transplant Congress
A Novel Approach to Preserve Pancreatic Islet Grafts in Extrahepatic Space for Reversal of Diabetes Using Parathyroid Gland Co-Transplantation
Intro: Islet transplantation can cure type 1 diabetes; however, multiple donors are needed due to extensive perioperative loss of islets away from their native blood…2018 American Transplant Congress
DSA with TCMR Identifies High Risk Renal Transplant Recipients That Can Be Predicted by Proinflammatory Transitional B Cells
Starzl Transplant Inst., Univ. of Pittsburgh, Pittsburgh.
Post-transplant DSA is strongly associated with poor graft outcomes but has limited predictive value. In this prospective study we aimed to risk-stratify patients with early…2018 American Transplant Congress
Hard-To-Place Kidney Offers: System- Level Predictors of Discard
Background: Deceased-donor kidney discard rates remain high. Inefficiencies in the allocation of hard-to-place kidneys may be contributing to discard suggesting that system-level factors represent opportunities…2018 American Transplant Congress
Donor Safety in Obese Patients: 1038 Consecutive Robotic Living Donor Nephrectomies
1Surgery, University of Illinois, Chicago, IL; 2Surgery, University of Virginia, Virginia, VA.
Laparoscopic donor nephrectomy has been a widely accepted technical improvement in kidney transplantation. Since 2000, we have introduced robotic living donor nephrectomy (RLDN) in our…2018 American Transplant Congress
Post-Transplant Outcomes under the New HCC Exception Policy
Surgery, Johns Hopkins Medical Institute, Baltimore, MD.
In October 2015, OPTN implemented a new policy for liver allocation, under which hepatocellular carcinoma (HCC) patients receive exception points only after a 6-month delay.…2018 American Transplant Congress
HIV, HBV, and HCV Screening with NAT and Serology in the OPO Setting
1UMass Memorial Medical Center, Worcester, MA; 2Northwestern University, Chicago, IL.
Background:In December 2014, the Organ Procurement & Transplantation Network updated policy to mandate screening with nucleic acid tests (NAT) for hepatitis C virus (HCV) in…
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