ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Immune Modulatory Effect of Thalidomide and Dexamethasone Co-Treatment on Murine Splenocytes

    E. Kim,1,2 J. Kim,1 K. Huh,1,3 Y. Cho,1 M. Kim,1,3 Y. Kim,1,3 B. Kim.1,4

    1The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; 2Brain Korea 21 PLUS Project for Medical Science, Yonsei University, Seoul, Korea; 3Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea; 4Department of Internal Medicine, Nephrology, Yonsei University College of Medicine, Seoul, Korea.

    Thalidomide (TM) is known to have anti-inflammatory effects and dexamethasone (DX) is also well known to reduce inflammation and inhibit inflammatory cytokine production. Clinically, combinatorial…
  • 2018 American Transplant Congress

    Pumping Donor Kidneys Reduces DGF and Improves Allograft Survival without Affecting Rejection Rates

    M. Samoylova, A. Nash, T. Brennan.

    Surgery, Duke University, Durham, NC.

    Recent evidence suggests that hypothermic machine perfusion of donor kidneys reduces delayed graft function (DGF), but data is sparse on its effect on allograft rejection.…
  • 2018 American Transplant Congress

    Implementation of Intensive Standardized Follow-Up in Kidney Transplant Recipients

    A. Crane, M. Eltemamy, T. Coy, P. Babbar, A. Sun, D. Jacobsen, M. Ponziano, E. Poggio, A. Wee, R. Fatica, V. Krishnamurthi.

    Cleveland Clinic, Cleveland.

    Introduction & Objective: Kidney transplant recipients have higher rates of prolonged hospitalization and readmission rates. We aimed to identify modifiable predictors of 30-day readmission and…
  • 2018 American Transplant Congress

    Association between Genetic Polymorphisms of Fc Gamma Receptor Genes (FcgR) and the Development of Donor Specific Antibodies (DSA) after Kidney Transplant

    D. Min,1 Y. Chang,2 T. Shah.3

    1College of Pharmacy, Western University of Health Sciences, Pomona, CA; 2National Institute of Transplantation Foundation, Los Angeles, CA; 3Multi-Organ Transplant Center, St. Vincent Medical Center, Los Angeles, CA.

    Background: Antibody mediated rejection (AMR) is one of the most important barriers to improve long-term kidney transplant outcomes. The presence of donor specific antibodies (DSA)…
  • 2018 American Transplant Congress

    Antiproteinuric Effect of Spironolactone in Renal Transplantation: Effectiveness and Clinical Outcomes

    M. Sousa, C. Do Valle, G. Rivelli, L. Camargo, R. Zollner, M. Mazzali.

    University of Campinas, Campinas, Sao Paulo, Brazil.

    Background: aldosterone is involved in development of fibrosis in kidney transplantation. Blockade of aldosterone receptor appears to be effective in treatment for chronic allograft dysfunction,…
  • 2018 American Transplant Congress

    Kidney Transplantation (KTx) Using Kidneys from Deceased Donors (DD) with Severe Acute Kidney Injury (AKI) Requiring Renal Replacement Therapy (RRT)

    A. Srinivasan, R. Heilman, A. Kumar, H. Khamash, M. Smith, K. Reddy, A. Moss.

    Mayo Clinic, Phoenix.

    Background:Transplant centers are reluctant to accept kidneys from DD with severe AKI necessitating utilization of RRT. The aim of this study is to determine the…
  • 2018 American Transplant Congress

    Predictors of Kidney Transplant Recipient Readmissions

    A. Crane, M. Eltemamy, D. Jacobsen, T. Coy, A. Sun, P. Babbar, M. Ponziano, E. Poggio, A. Wee, R. Fatica, V. Krishnamurthi.

    Glickman Urology and Nephrology, Cleveland Clinic, Cleveland.

    Introduction: Readmission rates for kidney transplant recipients is high and widely variable with a range of 18-47% nationwide. We aimed to characterize kidney transplant patients…
  • 2018 American Transplant Congress

    One-Year Outcomes in Patients with Advanced Liver Fibrosis or Compensated Cirrhosis from Chronic Hepatitis C Receiving Kidney Transplant Alone

    P. Brown, F. Kumssa, D. Venkat.

    Henry Ford Hospital, Detroit.

    Background: Hepatitis C (HCV) was difficult to treat post-kidney transplant prior to the direct acting antiviral (DAA) era. As such patients with advanced fibrosis and…
  • 2018 American Transplant Congress

    Serum Beta-(1,3)-D-Glucan as a Case-Finding Tool during an Outbreak of Pneumocystitis jirovecii Pneumonia in Abdominal Transplant Patients

    J. Mittal, J. Mogollon, K. Cowman, P. Nori, V. Muggia, G. Minamoto, Y. Puius.

    Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY.

    Background: Pneumocystis jirovecii pneumonia(PJP) in solid organ transplant (SOT) recipients carries significant morbidity and mortality. There is mounting evidence for ongoing risk of PJP in…
  • 2018 American Transplant Congress

    Reduced Ratio of FoxP3/ RORγt Gene Expression, in Peripheral Blood, is Associated with Acute Allograft Rejection in Recipients with Kidney Transplantation

    R. Dhital,1,2 R. Minz,3 M. Minz,1,4 A. Sharma,1 R. Nada,5 S. Singh,1 D. Kenwar,1 S. Anand.3

    1Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; 2Vaccines and Immunity, Nationwide Children's Hospital, Columbus, OH; 3Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India; 4Organ Transplantation, Fortis Hospital, Mohali, Punjab, India; 5Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, UT, India.

    Introduction:FoxP3 has been well established as an indispensable protein that is required in the development and function of regulatory T cells. On the other hand,…
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