ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Persistence and Homing of Autologous Donor-Reactive Ex-Vivo Expanded Regulatory T Cells to Heart Allografts in Lymphodepleted Recipient Monkeys

    M. Ezzelarab, Z. Hong, A. Zahorchak, L. Lien, T. Nakao, H. Dai, D. van der Windt, A. Perez-Gutierrez, J. Bhama, A. Thomson.

    Surgery, Starzl Transplantation Institute, Pittsburgh, PA.

    Background:Infusion of ex vivo expanded regulatory T cells (Treg) is a promising therapy to prevent allograft rejection. Trafficking of Treg to allografts and secondary (2ry)…
  • 2018 American Transplant Congress

    Assessment of Bile Production and Quality during Normothermic Ex Vivo Liver Perfusion to Predict Biliary Injury

    D. Kollmann,1 I. Linares,1 S. Ganesh,1 R. Rosales,1 M. Hamar,1 P. Urbanellis,1 A. Wiebe,1 P. Yip,2 O. Adeyi,2 M. Selzner,1 N. Selzner.1

    1Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada; 2Laboratory Medicine and Pathobiology, University Health Network, Toronto, Canada.

    Background. Liver transplantation (LT) with donation after circulatory death (DCD)-grafts is associated with higher risk for biliary strictures. We evaluated bile production and quality during…
  • 2018 American Transplant Congress

    Urine Podocin mRNA to Nephrin mRNA Ratio as a Marker of "Podocyte Stress" among Kidney Allografts Losing Function

    A. Naik,1 J. Aqeel,1 D. Cibrik,2 M. Samaniego,1 S. Wang,1 M. Chowdhury,1 F. Afshinnia,1 R. Wiggins.1

    1Univ of Michigan, Ann Arbor; 2Univ of Kansas, Kansas City.

    Increasing data supports the hypothesis that long term allograft loss-of-function is associated with progressive glomerulosclerosis (GS). In models of progressive GS the ratio of two…
  • 2018 American Transplant Congress

    Etiologies and Long-Term Outcomes of Acute Kidney Injury in Older Kidney Transplant Recipients

    R. Rodriguez, P. Amechi, V. Rao, D. Taber, M. Posadas Salas.

    Medical University of South Carolina, Charleston, SC.

    Older kidney transplant recipients face challenges of post-transplant complications related to frailty and comorbidity burden. They are particularly vulnerable to acute kidney injury (AKI) due…
  • 2018 American Transplant Congress

    C4d Staining and Graft Survival in Renal Transplant Recipients

    N. Mohiuddin, S. Agarwal, A. Patel, R. Prashar.

    Nephrology and Transplant, Henry Ford Hospital, Detroit, MI.

    Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or chronic antibody mediated rejection (AMR). Data on the significance of variable C4d…
  • 2018 American Transplant Congress

    Outcomes after Kidney Transplant (KTx) from Deceased Donors (DD) Aged ≥ 70

    A. Srinivasan, R. Heilman, H. Khamash, K. Reddy, A. Moss.

    Mayo Clinic, Phoenix.

    Background:There has been an increase in DD aged 70 or greater and transplant centers are reluctant to accept these organs. The aim of this study…
  • 2018 American Transplant Congress

    Kidney Transplantation from Uncontrolled Donation after Circulatory Death, Good Outcomes after Very Long Time

    M. Molina,1 J. Cabrera,2 E. Gonzalez,1 A. Hernandez,1 P. Natalia,1 A. Andres.1

    1Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain; 2Department of Nephrology, Hospital Evangelico, Montevideo, Uruguay.

    Introduction: Kidney transplantation (KT) is the best renal replacement therapy but the shortage of organ is the main limitation. Uncontrolled Donation after Circulatory Death (uDCD)…
  • 2018 American Transplant Congress

    The Role of Pre-Emptive Antibiotic Therapy in Kidney Recipients of Donors with Urine-Only Positive Cultures

    P. Cabrera,1 A. Centeno,1 J. Revollo,1 J. Camargo.2

    1Department of Pharmacy, Jackson Memorial Hospital, Miami, FL; 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL.

    Background: Donor derived infections (DDIs) can lead to significant morbidity and mortality in solid organ transplant patients. In recent years, the disparity between the need…
  • 2018 American Transplant Congress

    Latent Tuberculosis Diagnosis Prior to Kidney Transplantation in a High Burden Country: Improvement with Serological Tests

    V. Garcia, G. Meinerz, C. da Silva, E. Keitel.

    Nephrology and Kidney Transplant Department, ISCMPA, Porto Alegre, Brazil.

    Introduction: Diagnosing and treating tuberculosis after kidney transplantation is challenging, and mortality is high. In an epidemiological study performed at our Center, there was an…
  • 2018 American Transplant Congress

    Diagnostic Performance of Blood Pressure Measurement Modality in Prospective Living Kidney Donors

    S. Armanyous, M. Lioudis, G. Thomas, E. Poggio, J. Augustine.

    Nephrology, Cleveland Clinic, Cleveland, OH.

    Background: Precise blood pressure (BP) measurement to exclude hypertension (HTN) is critical in evaluating living kidney donors (LKDs). 24-hour ambulatory blood pressure monitoring (ABPM) is…
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