ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Immunomonitoring of Operational Tolerance in Intestinal Transplantation

    O. Aguirre, B. Houlihan, T. Fishbein, A. Kroemer.

    Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    A. The purpose of this study is to immunocharacterize the first reported case of intestinal transplant (ITx) operational tolerance, in parallel with a stable ITx…
  • 2018 American Transplant Congress

    The Clinical Efficacy of Seasonal Influenza Vaccination – Characteristics of Two Outbreaks of Influenza A(H1N1) in Immunocompromised Patients

    I. Helanterä,1 R. Janes,2 V-.J. Anttila.3

    1Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; 2Department of Oncology, Helsinki University Hospital, Helsinki, Finland; 3Department of Infectious Diseases, Helsinki University Hospital, Helsinki, Finland.

    A. Background. Influenza A(H1N1) causes serious complications in immunocompromised patients. The efficacy of seasonal influenza vaccination in transplant recipients and patients receiving chemotherapy has been…
  • 2018 American Transplant Congress

    Clostridium difficile Recurrence in Abdominal Organ Transplant Recipients: Metronidazole versus Oral Vancomycin

    A. Moorman,1 S. Todd,1 G. Lyon III,2 H. Triemer.1

    1Department of Pharmaceutical Services, Emory University Hospital, Atlanta, GA; 2Division of Infectious Diseases, Emory University, Atlanta, GA.

    Clostridium difficile infection (CDI) is one of the most common hospital-acquired infections among the general inpatient population with recurrence rates of 20-30% despite appropriate treatment.…
  • 2018 American Transplant Congress

    TACI Polymorphisms Associated with Allograft Rejection in Mice and in Man

    M. Barbosa,1 E. Farkash,2 J. Platt,3 M. Cascalho.3

    1Surgery, University of Michigan, Ann Arbor, MI; 2Pathology, University of Michigan, Ann Arbor, MI; 3Surgery/Microbiology and Immunology, University of Michigan, Ann Arbor, MI.

    Trans-membrane Activator and CAML Interactor (TACI) controls B cell differentiation and memory and exists as numerous allelic variants in healthy individuals. In fact, TACI is…
  • 2018 American Transplant Congress

    UPMC Living Donor Champion Program

    C. Caruso, C. Zell, G. Swaytha, B. Angela, S. Sarah, L. Elaine, P. Susan, W. Travis, H. Abhinav.

    Transplant Services, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Aims: Living donation is a good option to address organ shortage and waitlist mortality, but finding a living donor can be a challenge. The goal…
  • 2018 American Transplant Congress

    Persistence and Homing of Autologous Donor-Reactive Ex-Vivo Expanded Regulatory T Cells to Heart Allografts in Lymphodepleted Recipient Monkeys

    M. Ezzelarab, Z. Hong, A. Zahorchak, L. Lien, T. Nakao, H. Dai, D. van der Windt, A. Perez-Gutierrez, J. Bhama, A. Thomson.

    Surgery, Starzl Transplantation Institute, Pittsburgh, PA.

    Background:Infusion of ex vivo expanded regulatory T cells (Treg) is a promising therapy to prevent allograft rejection. Trafficking of Treg to allografts and secondary (2ry)…
  • 2018 American Transplant Congress

    Assessment of Bile Production and Quality during Normothermic Ex Vivo Liver Perfusion to Predict Biliary Injury

    D. Kollmann,1 I. Linares,1 S. Ganesh,1 R. Rosales,1 M. Hamar,1 P. Urbanellis,1 A. Wiebe,1 P. Yip,2 O. Adeyi,2 M. Selzner,1 N. Selzner.1

    1Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada; 2Laboratory Medicine and Pathobiology, University Health Network, Toronto, Canada.

    Background. Liver transplantation (LT) with donation after circulatory death (DCD)-grafts is associated with higher risk for biliary strictures. We evaluated bile production and quality during…
  • 2018 American Transplant Congress

    Urine Podocin mRNA to Nephrin mRNA Ratio as a Marker of "Podocyte Stress" among Kidney Allografts Losing Function

    A. Naik,1 J. Aqeel,1 D. Cibrik,2 M. Samaniego,1 S. Wang,1 M. Chowdhury,1 F. Afshinnia,1 R. Wiggins.1

    1Univ of Michigan, Ann Arbor; 2Univ of Kansas, Kansas City.

    Increasing data supports the hypothesis that long term allograft loss-of-function is associated with progressive glomerulosclerosis (GS). In models of progressive GS the ratio of two…
  • 2018 American Transplant Congress

    Etiologies and Long-Term Outcomes of Acute Kidney Injury in Older Kidney Transplant Recipients

    R. Rodriguez, P. Amechi, V. Rao, D. Taber, M. Posadas Salas.

    Medical University of South Carolina, Charleston, SC.

    Older kidney transplant recipients face challenges of post-transplant complications related to frailty and comorbidity burden. They are particularly vulnerable to acute kidney injury (AKI) due…
  • 2018 American Transplant Congress

    C4d Staining and Graft Survival in Renal Transplant Recipients

    N. Mohiuddin, S. Agarwal, A. Patel, R. Prashar.

    Nephrology and Transplant, Henry Ford Hospital, Detroit, MI.

    Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or chronic antibody mediated rejection (AMR). Data on the significance of variable C4d…
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