Am J Transplant, Volume 18, Suppl 3 Archives - Page 24 of 211 - ATC Abstracts

2018 American Transplant Congress
The Impact of Early versus Late Clinical Outcomes on Disparities in African-American Kidney Transplant Recipients
D. Taber, J. Fleming, Z. Su, P. Mauldin, J. McGillicuddy, S. Nadig, V. Rohan, P. Baliga, D. Dubay.
MUSC, Charleston, SC.
Background: It is important to better understand the impact of early and late clinical events on disparities in African-American (AA) kidney transplant (KTX), which will…
2018 American Transplant Congress
Donor Bone Marrow CXCR4+ Foxp3+ Treg Cells Are Essential for Costimulation Blockade-Induced Long-Term Survival of Murine Limb Transplants
L. Wang,¹ Z. Wang,¹ R. Han,¹ G. Ge,¹ L. Levin,² M. Levine,² W. Hancock.^1,2
¹CHOP, Philadelphia; ²UPenn, Philadelphia.
Vascularized composite allotransplantation (VCA) would likely be more widely performed if maintenance immunosuppression was not essential for graft acceptance. Accordingly, we used murine models of…
2018 American Transplant Congress
Improving DCD Livers Graft Function Using CD47 Blockade in the Setting of Normothermic Liver Perfusion
S. Garcia-Aroz,¹ M. Xu,¹ X. Wang,¹ J. Hollingshead,¹ A. Khan,¹ B. Banan,¹ L. Kang,² Z. Zhang,¹ G. Upadhya,¹ Y. Lin,¹ P. Manning,³ W. Chapman.¹
¹Surgery, Washington University, St. Louis; ²Pathology, Washington University, St. Louis; ³Arch Oncology, St. Louis.
Background: Towards the goal of utilizing more livers for transplantation, transplant centers are looking to increase the use of organs from marginal donors. Livers from…
2018 American Transplant Congress
Extended Experience Using Tocilizumab (Anti-IL6R, TCZ) for the Treatment of Chronic Antibody Mediated Rejection (CABMR)
J. Choi,¹ O. Aubert,² S. Louie,¹ N. Ammerman,¹ A. Vo,¹ A. Peng,¹ E. Huang,¹ R. Najjar,¹ D. Puliyanda,¹ S. Sethi,¹ M. Haas,¹ K. Lim,¹ A. Loupy,² S. Jordan.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Paris Translational Center for Organ Transplantation, Paris, France.
Introduction: Disruption of the IL-6/IL-6R pathways may have benefits in treating allograft rejection. We reported our experience with anti-IL-6R (TCZ) as a treatment for CABMR…
2018 American Transplant Congress
Probability of Developing Chronic Kidney Disease 1 Year after Living Donor Nephrectomy Correlates with Baseline Kidney Volume and Function
I. Hall, A. Shaaban, S. Beddhu, F. Shihab.
University of Utah, Salt Lake City, UT.
Purpose: Living kidney donor outcomes are tremendously important, especially given expanding donor eligibility. Relative to other predictors, the relationship between remaining kidney volume and post-donation…
2018 American Transplant Congress
Isolated Pre-Transplant Angiotensin II Type I Receptor Antibodies (AT1R Ab) Are Not Associated with Reduced Graft Function or Hypertension (HTN) in Pediatric Kidney Transplant (Ped KTx) Patients (pts)
H. Pizzo, J. Choi, M. Haas, X. Zhang, E. Kamil, I. Kim, S. Jordan, D. Puliyanda.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Pre-tx donor-specific antibodies (DSA) raises the risk for antibody-mediated rejection (ABMR) and graft dysfunction. The role of AT1R Ab is unclear. In adults, post-tx…
2018 American Transplant Congress
Analyzing Geographic Disparity in the US Heart Allocation System
F. Karami,¹ M. Nayebpour,² M. Gentili,¹ N. Koizumi,² A. Rivard.³
¹Industrial Engineering, University of Louisville, Louisville, KY; ²Schar School of Policy and Government, George Mason University, Arlington; ³Department of Radiology, Cleveland Clinic, Abu Dhabi, United Arab Emirates.
Introduction: In the United States, the system to allocate solid organs for transplantation is regulated and maintained by the United Network for Organ Sharing (UNOS).…
2018 American Transplant Congress
Survey of Rabbit Anti-Thymocyte Globulin Usage for Kidney Transplant Induction Therapy in the United States
K. Foster,¹ A. Dodson,² K. Gutierrez.²
¹Samford University McWhorter School of Pharmacy, Birmingham, AL; ²Comprehensive Transplant Institute, UAB Hospital, Birmingham, AL.
Background: Rabbit anti-thymocyte globulin (rATG) has become the most widely used induction agent in kidney transplantation (KTx) and has recently received FDA approval for this…
2018 American Transplant Congress
Autologous Adipose-Derived Stem Cells with In Vivo Immunomodulatory Properties Can Be Generated in Allograft Recipients under Immunosuppression
A. Sicard,¹ J. Rodriguez,² P. Petruzzo,³ J. Kanitakis,⁴ O. Damour,² L. Badet,⁵ A. Gazarian,⁶ F. Buron,¹ O. Thaunat,¹ K. Tarte,⁷ C. Mesnard,⁷ C. Auxenfans,² E. Morelon.¹
¹Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital, Lyon, France; ²Cells and Tissue Bank, Edouard Herriot Hospital, Lyon, France; ³University of Cagliari, Cagliari, Italy; ⁴Department of Dermatology, Edouard Herriot Hospital, Lyon, France; ⁵Department of Urology and Transplantation, Edouard Herriot Hospital, Lyon, France; ⁶Clinique du Parc, Lyon, France; ⁷University Hospital of Rennes, Rennes, France.
PurposeTo determine if it is possible to generate mesenchymal stem cells (MSC) with potent in vivo immunomodulatory properties in allograft recipients under immunosuppression, we analyzed…
2018 American Transplant Congress
A Retrospective Review of De Novo Coccidioidomycosis among Remote Solid Organ Transplant Recipients in Arizona
T. Zangeneh,¹ J. August,¹ N. Beatty,¹ K. Asbury,² L. Mi,² J. Blair.²
¹Medicine/Division of Infectious Diseases, University of Arizona/Banner University Medical Center/Valley Fever Center for Excellence, Tucson, AZ; ²Medicine/Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, AZ.
Background: Solid organ transplant (SOT) recipients residing in a Coccidioides-endemic region that acquire infection are at risk for complicated and protracted infection. Following transplantation, prophylaxis…