Am J Transplant, Volume 18, Suppl 3 Archives - Page 24 of 211 - ATC Abstracts

2018 American Transplant Congress
A Novel Preservation Solution for Lung That Improves Cell Viability and Tissue Architecture
J. Friedman,¹ M. Samamrco,¹ L. Marrero,¹ B. Bunnell,¹ D. Spyropoulos.²
¹Tulane University, New Orleans; ²MUSC, Charleston.
Backgroud: Only 20% of donor lungs are used for transplant and 10 y survival of recipients is low. Many patients die within 30 d of…
2018 American Transplant Congress
Gr1^– Macrophages Play Critical Roles in Liver Inflammation Resolution after IRI via Efferocytosis
M. Ni,^1,2 H. Wang,^1,2 R. Busuttil,¹ J. Kupiec-Weglinski,¹ X. Wang,² Y. Zhai.¹
¹Surgery, David Geffen School of Medicine-UCLA, Los Angeles, CA; ²Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiansu, China.
Inflammation resolution is an integral part of liver ischemia reperfusion injury (IRI), which affects not only the severity of tissue damage, but more importantly its…
2018 American Transplant Congress
Histone Deacetylase-6 Inhibition Mitigates Liver Ischemia-Reperfusion Injury and Acetaminophen Toxicity in Mice
S. Concors,¹ D. Murken,¹ D. Aufhauser,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,⁴ W. Hancock,^3,4 M. Levine.^1,2
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Surgery, Children's Hospital of Philadelphia, Philadelphia, PA; ³Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ⁴Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Ischemia/reperfusion injury (IRI) leads to poor outcomes and early graft loss in liver transplantation. Understanding the mechanisms of liver IRI may aid in prevention…
2018 American Transplant Congress
CD19+ Cell Ratio as a Predictive Marker of Antibody Mediated Rejection in ABO Incompatible Kidney Transplantation
K. Unagami,¹ R. Maenosono,² M. Furusawa,² Y. Kakuta,² M. Okumi,² H. Ishida,² K. Tanabe,² K. Nitta.¹
¹Nephrology, Tokyo Women's Medical University, Tokyo, Japan; ²Urology, Tokyo Women's Medical University, Tokyo, Japan.
Background: Rituximab has been suggested to deplete B cells and decrease the possibility of antibody mediated rejection (AMR) in ABO-incompatible living kidney transplantation (ABO-ILKT). We…
2018 American Transplant Congress
The Impact of Pre-Transplant Donor Specific Antibodies (DSA) on AMR Rates in HIV-Infected Kidney Transplant Recipients Inducted with IL-2 RA
S. Farouk, B. Rollins, V. Delaney, N. Singh, V. Sehgal, R. Kent, M. Menon, R. Shapiro, S. Florman, G. DeBoccardo.
Recanati Miller Transplant Institute, Icahn School of Medicine at Mt. Sinai, New York, NY.
Background: 1-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. We report the…
2018 American Transplant Congress
Antibody Mediated Kidney Transplant Rejection Treated with Bortezomib – Case Series from a Single Center
G. Piecha,¹ R. Król,² H. Karkoszka,¹ A. Wiecek.¹
¹Department of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland; ²Department of General, Vascular and Transplantation Surgery, Medical University of Silesia, Katowice, Poland.
Acute antibody mediated kidney transplant rejection (ABMR) is not a frequent complication but may have a catastrophic consequences for graft survival. Between January 2015 and…
2018 American Transplant Congress
Mid-Term Outcome of Donor Specific Antibody Positive Deceased Donor Kidney Transplantation with Peri-Transplant Desensitization
K. Osickova,¹ P. Hruba,² J. Slatinska,¹ A. Slavcev,² J. Fronek,² E. Honsova,² O. Viklicky.¹
¹Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; ²Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Donor specific HLA-antibodies (DSA) remain a large barrier to successful kidney transplantation and there is a limited knowledge about desensitization strategies in deceased donor programs.Anti…
2018 American Transplant Congress
Desensitization to Facilitate Matching in a Large, National Kidney Paired Exchange Clearinghouse
C. Holscher,¹ A. Thomas,¹ K. Jackson,¹ C. Haugen,¹ M. Ronin,² A. Waterman,^3,4 A. Massie,^1,5 J. Garonzik Wang,¹ D. Segev.^1,5
¹Johns Hopkins School of Medicine, Baltimore; ²National Kidney Registry, New York; ³David Geffen School of Medicine at UCLA, Los Angeles; ⁴Terasaki Research Institute, Los Angeles; ⁵Johns Hopkins School of Public Health, Baltimore.
In kidney paired exchange (KPE) programs, the use of incompatible transplantation has been necessary to prevent long waiting times for sensitized candidates and to facilitate…
2018 American Transplant Congress
Tuberculosis among Kidney Transplant Patients Compared to Dialysis and Non-Dialysis CKD Patients over a Decade Period
A. Metry, I. Al Salmi, F. Al Ismaili, A. Hola, F. Shaheen, I. Al Salmi.
The Renal Medicine, The Royal Hospital, Muscat, Oman; The Renal Medicine, The Royal Hospital, Muscat, Oman; The Renal Medicine, The Royal Hospital, Muscat, Oman; The Renal Medicine, The Royal Hospital, Muscat, Oman; SCOT, SCOT, Riyadh, Saudi Arabia; The Renal Medicine, The Royal Hospital, Muscat, Oman.
USRDS showed that 1.2% & 1.6% incidences of tuberculosis-TB in patients on peritoneal dialysis and hemodialysis-HD, respectively. Kidney transplant-KTX patients have higher rates.We studied the…
2018 American Transplant Congress
Regression of Left Atrial Diameter after Kidney Transplantation is Associated with Prolonged Survival: An Observational Study
A. Kainz,¹ F. Regele,¹ M. Kammer,² A. Beer,³ R. Steringer-Mascherbauer,⁴ T. Binder,⁵ R. Oberbauer.¹
¹Nephrology, Medical University of Vienna, Vienna, Austria; ²CeMSIIS, Medical University of Vienna, Vienna, Austria; ³Nephrology, Medical University of Innsbruck, Innsbruck, Austria; ⁴Cardiology, Ordensklinikum Linz, Linz, Austria; ⁵Cardiology, Medical University of Vienna, Vienna, Austria.
BackgroundThe risk of cardiovascular death in patients on dialysis is dramatically elevated but can be reduced by renal transplantation. We previously showed that left atrial…