ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    The Effect of Perioperative Antiplatelet/Anticoagulant Therapy on the Incidence of Early Postoperative Thromboembolic Complications and Bleeding in Kidney Transplantation – A Dual Center Retrospective Cohort Study of 2000 Kidney Transplant Recipients

    T. van den Berg,1 R. Minnee,2 G. Nieuwenhuijs-Moeke,3 S. Bakker,4 R. Pol.1

    1Department of Surgery, University Medical Center Groningen (UMCG), Groningen, Netherlands; 2Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; 3Department of Anesthesiology, UMCG, Groningen, Netherlands; 4Department of Internal Medicine-Nephrology, UMCG, Groningen, Netherlands.

    Thromboembolic complications (TECs) are dreaded complications after kidney transplantation (KTx). Consequences are severe and can result in delayed graft function or even graft loss. Perioperative…
  • 2018 American Transplant Congress

    Survival Benefit of Partial Grafts in Pediatric Candidates with Acute Liver Failure Awaiting Liver Transplantation: SRTR Analysis over 26 Years

    D. Firl, K. Sasaki, C. Quintini, B. Eghtesad, C. Miller, K. Hashimoto.

    CCF, Cleveland.

    Objective: Pediatric fulminant hepatic failure (PFHF) is a devastating condition which portends a poor prognosis without liver transplantation (LT). In comparison to adult candidates, there…
  • 2018 American Transplant Congress

    Declining Number of Pancreas after Kidney Transplants Despite Significant Improvement in Outcome

    A. Gruessner,1 M. Laftavi,2 O. Pankewycz,2 R. Gruessner.1

    1SUNY Downstate Medical Center, Brooklyn, NY; 2SUNY Upstate Medical University, Syracuse, NY.

    Introduction: The number of whole organ pancreas transplants declined significantly over the past 15 years. The largest decrease was seen in pancreas after kidney (PAK)…
  • 2018 American Transplant Congress

    Taking Your Center's Temperature: Using a Heat Map to Target Your Transplant-Specific Education for Regulatory Compliance

    J. Anderson, D. Cassidy, D. Dubay, P. Hart, A. Hauser, N. Pilch.

    Medical University of South Carolina, Charleston.

    Background: Large, multi-organ transplant centers struggle with implementation of a comprehensive strategy for development and execution of a Transplant-specific education plan. Regulatory requirements for staff…
  • 2018 American Transplant Congress

    Allogeneic T Follicular and T Conventional Responses Assessed by Proliferation, Cytokine Production, and TCR Clonality

    C. Macedo,1 M. Yamada,1 X. Gu,1 M. Suchoroski,2 D. Hamm,2 M. Kaplan,2 D. Metes.1

    1Thomas E. Starzl Transplantation Institute, Pittsburgh; 2Adaptive Biotechnologies, Seattle.

    Background: Human CD4+ T cell allo-immunity plays pivotal roles during cellular and humoral allograft rejection. Our previous analysis showed that allo-reactive precursors were present in…
  • 2018 American Transplant Congress

    Trends in Liver Transplantation with Older Liver Donors in the United States

    C. Haugen, X. Luo, A. Thomas, C. Holscher, J. Garonzik-Wang, M. McAdams-DeMarco, D. Segev.

    Surgery, JHU, Baltimore.

    As the US population ages, older liver donors (OLDs) represent a potential expansion of the donor pool. Historically, grafts from OLDs have been associated with…
  • 2018 American Transplant Congress

    Gut Microbiota Dysbiosis is an Independent Risk Factor for Development of Urinary Tract Infections in Kidney Transplantation

    J. Lee,1 A. Sholi,1 C. Gong,1 M. Magruder,1 S. Albakry,1 E. Edusei,1 B. Botticelli,1 D. Dadhania,1 M. Lubetzky,1 Y. Taur,2 L. Ling,2 E. Pamer,2 M. Suthanthiran.1

    1Weill Cornell, NY, NY; 2Memorial Sloan Kettering, NY, NY.

    INTRODUCTION. We examine the relationship between the gut microbiota and development of Escherichia and Enterococcus urinary tract infections (UTIs).METHODS. We recruited 170 kidney transplant recipients…
  • 2018 American Transplant Congress

    Validating Molecular Microscope Readings and Estimating Agreement with Histology

    P. Halloran, J. Reeve, The INTERCOMEX Study Group.

    ATAGC, Edmonton, Canada.

    We previously described a microarray diagnostic system (MMDx) for rejection in 1208 kidney transplant biopsies (J. Reeve et al. JCI Insight 2 (12), 2017). The…
  • 2018 American Transplant Congress

    Donation after Circulatory Death Donor Liver Transplantation without Ischemic Cholangiopathy: Is It Time to Expand DCD Liver Donor Pool?

    C. Kubal,1 P. Mihaylov,1,2 B. Ekser,1 A. Cabrales,1 J. Fridell,1 R. Mangus.1

    1Transplant Surgery, Indiana University, Indianapolis; 2Division of General Surgery, IRCCS Policlinico San Matteo Foundation, University of Pavia, Lombardy, Italy.

    Background: To prevent ischemic cholangiopathy (IC) after liver transplantation (LT), a protocol optimizing peri-operative conditions along with thrombolytic (tissue plasminogen activator) donor flush during DCD…
  • 2018 American Transplant Congress

    Ablation of Both mTOR and STAT3 in T Cells Induces Heart Transplant Acceptance in Donor Skin-Sensitized Mice

    A. Xie,1,2 W. Chen.2,3

    1Division of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China; 2Center for Immunobiology and Transplantation Research, Houston Methodist Research Institute, Houston, TX; 3Department of Surgery, Weill Cornell Medical College of Cornell University, New York, NY.

    Allogeneic memory T cell response precludes the induction of transplant acceptance; how this process is regulated at the molecular level remains unclear. Both mTOR and…
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