2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…2018 American Transplant Congress
Comparison of Outcomes in African-American and White Primary Kidney Transplant Recipients: A Matched-Pair Analysis
SUNY Downstate Medical Center, Brooklyn, NY.
Background: Racial differences in clinical and sociodemographic characteristics have been well recognized. This study aims to assess outcomes in African-American (AA) and white primary deceased…2018 American Transplant Congress
Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…2018 American Transplant Congress
Characteristics and Outcomes of Kidney Transplant Recipients with More Than 25 Years of a Functioning Graft
University of Wisconsin, Madison.
Background: There is limited information on clinical characteristics and outcomes of kidney transplant recipients (KTRs) with more than 25 years of graft survival.Methods: We addressed…2018 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85: The Organ is Not Wholly to Blame
Background: High kidney donor profile index (KDPI)>85% organs are increasingly discarded, suggesting missed opportunities to provide patients the benefits of transplantation. Herein, we report the…2018 American Transplant Congress
Donor Acute Kidney Injury Does Not Affect Fibrosis on 1 Year Post-Transplant Kidney Biopsy
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.
PurposeThe use of kidneys from deceased donors with acute kidney injury (AKI) at the time of donation is a potential method by which to expand…2018 American Transplant Congress
Impact of Direct Antiviral Therapy for Hepatitis C on Acute Rejection and DSA Formation in Kidney Transplant Recipients
Cleveland Clinic, Cleveland, OH.
Background: Hepatitis C virus infection (HCV) has historically portended a poor outcome after kidney transplantation. With recent advent of direct antiviral agents (DAA), there has…2018 American Transplant Congress
Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant
Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…2018 American Transplant Congress
Prevalence of Metabolic Syndrome (MetS) and Insulin Resistance in Living Kidney Donors
Houston Methodist Hospital, Houston, TX.
Living kidney donors (LD) are routinely evaluated for components of MetS such as diabetes (T2D), hypertension (HTN), and hyperlipidemia (HLD). MetS is associated with T2D,…2018 American Transplant Congress
Belatacept-Refractory CD8+CD28–CD38hi Effector/Memory T Cells Are Targeted by mTOR Inhibition Leading to a Preferential Loss of CD40L
Calcineurin inhibitors (CNIs) and corticosteroids (CSS) have substantial untoward side effects, most notably nephrotoxicity. Consequently, the FDA approved belatacept for maintenance immunosuppression. We recently completed…