2018 American Transplant Congress
Insulin Use after Pancreas Transplant: Implications for Post-Transplant Outcomes
We examined associations of insulin use after pancreas transplant with patient survival, and with kidney graft survival among simultaneous kidney-pancreas transplant (SKPT) recipients, in a…2018 American Transplant Congress
Patient Attitudes and Perceptions of Using Mobile Health Technology for Living Kidney Donor Follow-Up and Care Management
Living kidney donor (LKD) follow-up is imperative to understand and monitor long-term outcomes after living donor nephrectomy, yet donor engagement with transplant hospitals post-donation remains…2018 American Transplant Congress
IL-10 Requirement in In Vitro Expanded Breg-Mediated Allograft Tolerance is Tissue Specific
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Introduction:Regulatory B cells (Bregs) have shown several multiple mechanisms of suppression, including Treg induction and IL-10 production. Consistent with work of other groups on Breg…2018 American Transplant Congress
Immunomodulation of Alloantibody Responses
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
We have shown that i.v. exposure to MHC-mismatched donor PBMC using a novel, mild conditioning protocol results in B-cell tolerance with transient T-cell unresponsiveness. Here…2018 American Transplant Congress
Kidney Allografts Confer Tolerance upon Co-Transplanted Heart Allografts by Promoting Tregs
The same mixed chimerism-based protocol that induces tolerance of nonhuman primate kidney allografts results in rejection of heart allografts. However, when the two organs from…2018 American Transplant Congress
Association between Everolimus Trough Levels, Onset of Related Adverse Events, and Treatment Discontinuation after Liver Transplantation: 24-Month Results from the H2304 Study
Purpose: Evaluation of mammalian target of rapamycin inhibitor (mTORi)-related adverse events (AEs) and drug trough levels (C0) at onset may aid their management in liver…2018 American Transplant Congress
Enhancement of Endogenous omega-3 Protect against Ischemia-Reperfusion Renal Injury in Fat-1 Mice
Introduction : Fat-1 transgenic mice produce [omega]3-Polyunsaturated fatty acids ([omega]3-PUFAs) from [omega]6-Polyunsaturated fatty acids ([omega]6-PUFAs) without a dietary [omega]3-PUFAs supplement, leading to a high accumulation…2018 American Transplant Congress
Liver Biopsy Fibrosis Not Liver Imaging Predicts Survival after Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Hepatic dysfunction is common in patients with cardiomyopathy being evaluated for heart transplant (HT). ISHLT guidelines highlight the need for liver evaluation in patients…2018 American Transplant Congress
Kidney Graft Outcomes in Combined Heart-Kidney Transplantation: A UNOS Database Analysis 2000-2015
Indiana University, Indianapolis.
Background: Combined Heart-Kidney Transplantation (CHKT) is the optimal therapy for patients with advanced renal dysfunction. Our aim was to analyze kidney specific graft outcomes in…2018 American Transplant Congress
Risk of Infection in Treatment of Acute Cellular Rejection in Heart Transplant Recipients
Tampa General Hospital, Tampa, FL; University of North Carolina, Chapel Hill, NC.
There has been no publication of the incidence of infection (infxn) after the treatment of acute cellular rejection (ACR) in heart transplant recipients (HTR). We…
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