ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Evaluation of the Use of Oral Valganciclovir for the Treatment of Cytomegalovirus Infections in Pediatric Intestinal Transplant Recipients: A Single Center Review

    M. Henry, M. Vacha, M. Keck, D. Florescu.

    Nebraska Medicine, Omaha, NE.

    Purpose: To evaluate the safety and efficacy of oral valganciclovir in treating cytomegalovirus (CMV) infections in pediatric intestinal transplant recipients (pITR).Methods: This retrospective review included…
  • 2018 American Transplant Congress

    Impact of Influenza Vaccine Implementation by Transplant Pharmacy in Solid Organ Transplant Recipients

    S. Gattis,1 I. Yildirim,1,2 S. Serluco,1 C. McCracken,2 R. Liverman.1

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Emory University School of Medicine, Atlanta, GA.

    Background: In solid organ transplant (SOT) recipients, influenza infection can lead to subsequent graft dysfunction and mortality. In an effort to increase vaccination rates, transplant…
  • 2018 American Transplant Congress

    Bacterial Complications in Liver Transplant Recipients Undergoing Biliary Tract Manipulation: Effect of an Antibiotic Prophylaxis Protocol

    C. Clifford, N. Theodoropoulos, J. Daly, L. Gibson, S. Mehta, H. Malik, A. Bozorgzadeh.

    University of Massachusetts Medical School, Worcester, MA.

    Purpose: The purpose of this study was to evaluate incidence of bacteremia and outcomes in liver transplant recipients that had biliary tract manipulation before and…
  • 2018 American Transplant Congress

    In Vivo Administration of Plerixafor and Bortezomib Results in Bone Marrow Plasma Cell Mobilization and Death While Inducing Biphasic Plasma Cell Apoptosis in Peripheral Blood

    E. Woodle,1 S. Tremblay,1 C. Castro-Rojas,2 S. Knechtle,3 A. Shields,1 R. Alloway,1 H. Singh,2 J. Driscoll,1 D. Hildeman.2

    1U Cincinnati, Cincinnati; 2Cincinnati Children's, Cincinnati; 3Duke, Durham.

    Bone marrow (BM) plasma cells (PC) secreting HLA antibody (Ab) remain a persistent reservoir of donor specific Ab and present a significant hurdle to allograft…
  • 2018 American Transplant Congress

    Potential Impact of DCD Donor Recoveries on Heart Transplantation: Retrospective Analysis of a Limited UNOS Dataset

    J. Lindower,2 M. Farr,1 S. Taylor,2 U. Jorde,3 L. Chen,4 A. Gass,5 L. Truby,1 S. Delair,2 S. Pinney.6

    1New York Cardio-Thoracic Transplant Consortium, Troy, NY; 2Columbia/New York Presbyterian Hospital, New York; 3Montefiore Medical Center, Bronx, NY; 4Rochester University Medical Center, Rochester, NY; 5Westchester Medical Center, Valhalla, NY; 6Mount Sinai Medical Center, New York, NY.

    Purpose: To review the volume and quality of potential DCD (Donation after Cardiac Death) Heart Transplant (HT) donors in the US, evaluate trends over time…
  • 2018 American Transplant Congress

    Evaluation of Drug Action on IgM Memory B Cell Survival and Growth In Vitro; -Application for Individualized Immunosuppression after Kidney Transplants-

    Y. Matsuda,1 K. Takahashi,1 R. Imamura,2 N. Nonomura,2 Y. Yuzawa.1

    1Nephrology, Fujita Health University, Toyoake, Aichi, Japan; 2Urology, Osaka University, Suita, Osaka, Japan.

    (Background)Recently, the establishment of early diagnosis and treatment methods for antibody-mediated rejection (ABMR) has garnered much attention.Strong immunosuppression including desensitization is accompanied by severe side…
  • 2018 American Transplant Congress

    Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion

    Y. Boteon,1,2 R. Laing,1,2 A. Schlegel,2 J. Attard,1,2 L. Wallace,1 A. Smith,2 T. Perera,2 J. Isaac,2 D. Mirza,2 S. Afford,1 H. Mergental.2

    1National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; 2Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.

    Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
  • 2018 American Transplant Congress

    Comparison of Outcomes in African-American and White Primary Kidney Transplant Recipients: A Matched-Pair Analysis

    F. Tedla, A. Brar, D. John, N. Sumrani, R. Gruessner, A. Gruessner, M. Salifu.

    SUNY Downstate Medical Center, Brooklyn, NY.

    Background: Racial differences in clinical and sociodemographic characteristics have been well recognized. This study aims to assess outcomes in African-American (AA) and white primary deceased…
  • 2018 American Transplant Congress

    Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation

    B. Ho,1 S. Montag,1,2 H. Bhagat,3 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Inc., Northbrook.

    Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
  • 2018 American Transplant Congress

    Characteristics and Outcomes of Kidney Transplant Recipients with More Than 25 Years of a Functioning Graft

    S. Parajuli, D. Mandelbrot, F. Aziz, N. Garg, M. Mohamed, B. Muth, B. Astor, A. Djamali.

    University of Wisconsin, Madison.

    Background: There is limited information on clinical characteristics and outcomes of kidney transplant recipients (KTRs) with more than 25 years of graft survival.Methods: We addressed…
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