Am J Transplant, Volume 18, Suppl 3 Archives - Page 205 of 211 - ATC Abstracts

2018 American Transplant Congress
Human Atrial Natriuretic Peptide (hANP) in Cold Storage of Donation after Cardiac Death Livers: A New Tool for Protecting Vascular Endothelia?
Y. Nigmet,¹ K. Hata,¹ Y. Okamura,¹ I. Tamaki,¹ T. Tsuruyama,² H. Hirao,¹ T. Kubota,¹ J. Kusakabe,¹ J. Yoshikawa,¹ T. Goto,¹ T. Tajima,¹ H. Tanaka,¹ S. Uemoto.¹
¹Department of Surgery, Division of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University, Kyoto, Japan; ²Center for Anatomical, Pathological, and Forensic Medical Research, Kyoto University, Kyoto, Japan.
Aim: Current critical shortage of donor organs has led to acceptance of donation after cardiac death (DCD) livers for transplantation. Human atrial natriuretic peptide (hANP)…
2018 American Transplant Congress
Increased Length of Stay of the Donor Decreases Heart Transplant Recipient Survival
H. Copeland,¹ R. Talluri,² A. Panos,¹ R. Cochran,¹ L. Creswell,¹ D. Baran.³
¹Surgery, University of Mississippi Medical Center, Jackson, MS; ²Biostatistics, University of Mississippi Medical Center, Jackson, MS; ³Cardiology, Sentara Heart Hospital, Norfolk, VA.
Purpose: We hypothesize that the longer the cardiac donor is in the hospital prior to procurement, the worse the heart transplant (tx) recipient outcome for…
2018 American Transplant Congress
Less Induction Therapy Means Fewer Early Readmissions with No Change in Rejection or Infection
S. Kush, K. Boyle, J. Gray, S. Rega, I. Feurer, A. Shah, J. Lindenfeld.
Vanderbilt University Medical Center, Nashville, TN.
PURPOSE:In heart transplant, induction may allow for delay of calcineurin inhibitor initiation and renal recovery. Literature comparing lymphocyte-depleting and non-depleting induction conflicts in rejection rate…
2018 American Transplant Congress
Late Donor-Specific Antibody (Especially Class II) Development is Associated with an Increased Risk for Cardiac Allograft Vasculopathy
E. Kransdorf, J. Patel, M. Kittleson, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Development of donor-specific antibodies (DSA) following heart transplantation (HTx) impacts rejection, cardiac allograft vasculopathy (CAV), and survival. In addition, the timing of Ab development…
2018 American Transplant Congress
Temporal Changes in Impact of HLA Mismatch among Pediatric Kidney Transplant Recipients
J. Ruck, A. Massie, N. Desai, D. Segev, J. Garonzik-Wang.
Johns Hopkins University School of Medicine, Baltimore, MD.
U.S. pediatric deceased-donor kidney transplantation (pDDKT) allocation now deemphasizes HLA matching to improve equality in access to transplantation, but other national systems still consider HLA…
2018 American Transplant Congress
Informatics Tools for Mapping Molecular HLA Typing Data to UNOS Antigen Equivalencies
N. Kaur,¹ E. Kransdorf,² M. Pando,³ M. Maiers,⁴ L. Gragert.^1,4
¹Tulane University School of Medicine, New Orleans; ²Cedars-Sinai Heart Institute, Los Angeles; ³Baylor Scott and White, Temple; ⁴National Marrow Donor Program / Be The Match, Minneapolis.
Introduction:Molecular HLA typing must be converted to antigen equivalencies for entry into the UNOS database, UNet. Maintaining an up-to-date mapping table for this purpose has…
2018 American Transplant Congress
Immunosuppression and the Risk of Dementia among Older Kidney Transplant Recipients
M. McAdams DeMarco,¹ C. Haugen,¹ S. Bae,¹ K. Lentine,² D. Segev.¹
¹JHU, Baltimore; ²SLU, St. Louis.
Background: Older recipients have a high burden of dementia after kidney transplantation (KT). Factors contributing to post-KT dementia may include long-standing kidney disease, comorbid vascular…
2018 American Transplant Congress
Optimal Anti-Thymocyte Globulin Dose for Induction Immunosuppression in Kidney Transplantation
A. Mitrokhin, J. Goldman, B. Trivedi, V. Vidyasagar, N. Vadivel, M. Hart.
Organ Transplant Program, Swedish Medical Center, Seattle, WA.
Anti-thymocyte globulin (ATG) is used as induction immunosuppression in kidney transplantation to prevent allograft rejection. ATG causes dose-dependent lymphocyte depletion, yet optimal dose is unknown.…
2018 American Transplant Congress
Radioisotopic Evaluation of Glomerular Filtration Rate (GFR) before and 1 Year after Kindey Donation for Transplantation: The Concept of Estimated Renal Functional Reserve (eRFR)
V. Cantaluppi,¹ G. Guglielmetti,¹ M. Mora,¹ A. Airoldi,¹ F. Orsini,² M. Quaglia,¹ G. Sacchetti,² C. Ronco.³
¹Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy; ²Nuclear Medicine Unit, Maggiore della Carità University Hospital, Novara, Italy; ³Nephrology, Dialysis and Kidney Transplantation Unit, International Renal Research Institute (IRRIV), Vicenza, Italy.
Kidney donors (KD) develop a partial loss of renal function defined as Acute Kidney Injury (AKI). Recovery from AKI is due to renal functional reserve…
2018 American Transplant Congress
High Prevalence of Kidney Transplant-Associated Thrombotic Microangiopathy after ABO-Incompatible Kidney Transplantation: Risk Factors, Rapid Clinical Diagnosis, and Prompt Successful Treatment
K. Tanabe,¹ M. Okumi,¹ K. Unagami,² Y. Kakuta,¹ M. Inui,¹ H. Ishida.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
BackgroundKidney transplant-associated thrombotic microangiopathy (KTA-TMA) is a multifactorial inflammatory disorder and thrombotic disease of the microvasculature. It is characterized by hemolytic anemia, thrombocytopenia, and acute…