Am J Transplant, Volume 18, Suppl 3 Archives - Page 202 of 211 - ATC Abstracts

2018 American Transplant Congress
Antibody-Verified Eplet Mismatches as Determinants of Premature Kidney Transplant Loss
R. Sapir-Pichhadze,¹ X. Zhang,¹ A. Ferradji,¹ A. Madbouly,² S. Fingerson,² K. Tinckam,⁵ H. Gebel,³ H. Cardinal,⁴ B. Foster.¹
¹McGill University, Montreal, Canada; ²National Marrow Donor Program, Minneapolis; ³Emory University Hospital, Atlanta; ⁴CHUM, Montreal, Canada; ⁵University Health Network, Toronto, Canada.
Introduction: HLA matching at the epitope level offers new opportunities to identify compatible donors for transplant candidates. HLAMatchmaker deduces B-cell epitope ('eplets' in HLAMatchmaker) mismatches…
2018 American Transplant Congress
Relationship between Living Kidney Donor Follow-Up GFR and Recipient Graft Loss
C. Holscher,¹ T. Ishaque,¹ C. Haugen,¹ S. DiBrito,¹ K. Jackson,¹ A. Muzaale,¹ A. Massie,^1,2 M. Henderson,¹ J. Garonzik Wang,¹ D. Segev.^1,2,3
¹Johns Hopkins School of Medicine, Baltimore; ²Johns Hopkins School of Public Health, Baltimore; ³Scientific Registry of Transplant Recipients, Minneapolis.
In living kidney transplantation, it is reasonable to believe a donated kidney's function would be associated with the function of the donor's remaining kidney. Indeed,…
2018 American Transplant Congress
The Impact of Donor Specific Alloantibodies on Long-Term Outcomes of Liver Re-Transplantation
Q. Xu,¹ A. Skaro,² V. McAlister.²
¹Department of Pathology and Lab Medicine, University of Western Ontario, London, ON, Canada; ²Department of Surgery, University of Western Ontario, London, ON, Canada.
Despite reports that associate donor specific antibody (DSA) with rejection after liver transplantation, grafts are still allocated according to blood group (ABO) but not human…
2018 American Transplant Congress
Waiting for the Optimal Donor for MCS Patients Awaiting Heart Transplant
J. Kobashigawa, J. Patel, E. Kransdorf, R. Levine, S. Dimbil, E. Passano, L. Czer, J. Moriguchi, F. Arabia.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Patients (pts) bridged with mechanical circulatory support (MCS) may require more optimal donors for best outcome compared to non-bridged transplant recipients. MCS pts have…
2018 American Transplant Congress
Individualized Immunosuppression through Risk-Stratification in Renal Transplantation Preserves Excellent Outcomes at Three Years
J. Dann, A. Agarwal, M. Bradley, J. Geyston, W. Ally.
University of Virginia Health System, Charlottesville, VA.
Risk-stratification of renal transplant recipients based on immunologic risk factors allows for tailored immunosuppression (IS), but long term follow up is limited. This study evaluates…
2018 American Transplant Congress
Chronic Antibody Mediated Rejection in Renal Allografts Shows RNA Transcript Patterns That Evolve with Stage
A. Rosales,¹ B. Adam,² M. Mengel,² T. Oura,¹ M. Matsunami,¹ T. Kawai,¹ A. Cosimi,¹ R. Smith,¹ R. Colvin.¹
¹Massachusetts General Hospital, Boston, MA; ²University of Alberta, Edmonton, AB, Canada.
Purpose. Four stages of chronic antibody mediated rejection (CAMR) in renal allografts have been defined in humans and non-human primates (NHP), beginning with donor specific…
2018 American Transplant Congress
Tacrolimus and Isavuconazole Therapy: What about the Drug Interaction?
C. Gill,¹ N. Mercuro,¹ R. Kenney,¹ A. Jantz,¹ B. Summers,¹ N. Sulejmani,¹ S. Davis.^1,2
¹Henry Ford Hospital, Detroit; ²Wayne State University, Detroit, MI.
Introduction:Isavuconazole (ISV) is a triazole antifungal that is often utilized in solid organ transplant recipients (SOTR) for the treatment of invasive aspergillosis and mucormycosis. Isavuconazole…
2018 American Transplant Congress
Robotic Pancreas Transplantation in Obese Recipients: Preliminary Results
M. Spaggiari,¹ C. Di Bella,¹ P. Di Cocco,¹ F. Gheza,¹ E. Benedetti,¹ I. Tzvetanov,¹ J. Oberholzer.²
¹Surgery, University of Illinois, Chicago, IL; ²Surgery, University of Virginia, Virginia, VA.
IntroductionObesity is considered a relative contraindication to pancreas transplantation due to increased risks of wound and surgical related complications. Robotic surgery has never been applied…
2018 American Transplant Congress
Risk Factors for Invasive Fungal Infections among Lung Transplant Recipients
K. Whitaker, J. Anesi, E. Blumberg, L. Gardo, J. Lee, M. Crespo, C. Bermudez, L. Glaser, M. Wilck.
University of Pennsylvania, Philadelphia, PA.
Objective: Lung transplant (LT) recipients are at high risk of invasive fungal infections (IFI) with an estimated 1-year incidence of 8%. Despite advances in antifungal…
2018 American Transplant Congress
Effect of Acute Vascular Inflammation (v) on Death Censored Graft Failure (DCGF) Following Kidney Transplant (KTx)
J. Grande,¹ L. Hunsicker,² R. LeDuc,³ A. Matas, The DeKAF Consortium.
¹Pathology, Mayo Clinic, Rochester, MN; ²Int. Med., U Iowa, Iowa City, IA; ³Biostatistics and Surgery, U Minnesota, Minneapolis, MN.
The impact of acute vascular inflammation in acute cellular or humoral rejection following KTx, and the effect of isolated vascular inflammatory lesions on late DCGF,…