ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Preventing Recurrence of Incisional Hernia after Liver Transplantation

    J. Butler, D. O'Brien, J. Kays, C. Kubal, B. Ekser, J. Fridell, R. Mangus, J. Powelson.

    Transplant Surgery, Indiana University, Indianapolis, IN.

    Background: Incisional hernia is a well-known complication of orthotopic liver transplantation (OLT). Although factors that affect incidence of hernia after OLT have been described, recurrence…
  • 2018 American Transplant Congress

    A High Abdominal Aortic Calcification Score by Dual X-Ray Absorptiometry (DXA) is Associated with Cardiovascular Events after Kidney Transplantation

    S. Benjamens,1,2 R. A. Pol,1 A. W. Glaudemans,2 I. Wieringa,3 S. P. Berger,3 S. J. Bakker,3 R. H. Slart.2

    1Surgery, University Medical Center Groningen, Groningen, Netherlands; 2Medical Imaging Center, UMCG, Groningen, Netherlands; 3Nephrology, UMCG, Groningen, Netherlands.

    Introduction: It is unknown whether aortic calcification is associated with increased risk for cardiovascular events in renal transplant recipients. Therefore, this study focused on the…
  • 2018 American Transplant Congress

    Effect of Belatacept on Late Acute Rejection Episodes and Graft Loss in Young Adults between the Ages of 18-24 Years: Post-Hoc Analysis of BENEFIT Study

    A. Moudgil.

    Nephrology, Children National Health System, Washington, DC.

    Background: Recent data suggests higher incidence of late acute rejection (LAR) in young adults (18-24 years of age) causing graft loss just like adolescents due…
  • 2018 American Transplant Congress

    Superiority of Early Everolimus-Based Quadruple Immunosuppression versus Standard Triple Therapy after Lung Transplantation: 12 Months Results from Prospective 4EVERLUNG Study in Germany

    J. Gottlieb, C. Neurohr, J. Müller-Quernheim, H. Wirtz, B. Sill, H. Wilkens, V. Besa, C. Knosalla, M. Junge, C. Capusan, M. Strüber.

    Klinik, Hannover, Germany; Klinik, München, Germany; Klinik, Freiburg, Germany; Klinik, Leipzig, Germany; Klinik, Hamburg, Germany; Klinik, Homburg, Germany; Klinik, Essen, Germany; Klinik, Berlin, Germany; Novartis Pharma, Nürnberg, Germany; Novartis Pharma, Nürnberg, Germany; Klinik, Hannover, Germany.

    The 4Everlung trial was designed to evaluate the benefit of early everolimus (EVR)-based quadruple low immunosuppressive (IS) regimen on kidney function (RF) after LTx.4EVERLUNG is…
  • 2018 American Transplant Congress

    Anti-Angiotensin II Type 1-Receptor Antibodies (AT1R-Ab) Induce a Specific Phenotype of Rejection Distinct from HLA Antibody-Mediated Rejection

    C. Lefaucheur,1 D. Viglietti,1 O. Aubert,1 A. Philippe,2 P. Halloran,3 A. Loupy,1 D. Dragun.2

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2Medical Faculty of the Charité, Berlin, Germany; 3Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    AT1R-Ab have been associated with kidney allograft rejection; however, their ability to induce a specific rejection phenotype, independent of HLA-DSAs, has not been defined.In a…
  • 2018 American Transplant Congress

    Effect of Early Attainment of Everolimus Target Trough Levels on Efficacy-Safety Outcomes in De Novo Kidney Transplant Recipients: 12-Month Results from US92 and TRANSFORM Studies

    F. Shihab,1 Y. Qazi,1,2 V. Peddi,1 D. Shaffer,1 D. Kim,1,2 K. McCague,3 D. Patel,3 S. Mulgaonkar.1,2

    1US92 Study Group, Salt Lake City; 2TRANSFORM Study Group, East Hanover; 3Novartis Pharmaceuticals Corporation, East Hanover.

    Purpose: Attainment of everolimus (EVR) target trough level (C0 3-8ng/mL) is crucial in achieving comparable efficacy-safety with EVR+reduced (r) calcineurin inhibitor regimen (CNI; tacrolimus [TAC]…
  • 2018 American Transplant Congress

    Estimated GFR at Donor Screening and Achieved Measured GFR after Living Kidney Donation

    M. van Londen, J. van der Weijden, S. Bakker, S. Berger, J. Sanders, G. Navis, M. de Borst.

    Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands.

    Study Purpose: Accurate pre-donation renal function estimation is important to minimize the risk of future severe renal function impairment in living kidney donors. Recent studies…
  • 2018 American Transplant Congress

    Hidden Risk of Liver Transplantation for Nonalcoholic Steatohepatitis: A Propensity Score Matched Study

    S. Nagai,1 R. Schilke,1 M. Safwan,1 M. Rizzari,1 K. Collins,1 A. Yoshida,1 M. Abouljoud,1 D. Moonka.2

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI.

    Aim: There is a recent shift in the number of liver transplants (LT) performed in patients with hepatitis C (HCV) to those with non-alcoholic steatohepatitis…
  • 2018 American Transplant Congress

    Temporal and Geographical Trends of Intestinal Transplantation in the USA

    M. Segovia,1 S. Jafri,3 B. Summers,3 T. Schiano,2 T. Pietrowsky,3 A. Al-Osaimi,5 A. Mavis,1 S. Horslen.4

    1Duke Univ, Durham; 2Mt Sinai Hosp, NY; 3Henry Ford Hosp, Detroit; 4Seattle Children's Hosp, Seattle; 5Temple Univ, Philadelphia.

    Intestinal transplantation (IT) is uncommon compared to other organ transplants. We examined the temporal and geographical trends of centers that perform IT in the USAWe…
  • 2018 American Transplant Congress

    Graft Dendritic Cell p40 Homodimers Activate Donor-Reactive Endogenous Memory CD8 T Cells within Higher Risk Allografts

    H. Tsuda, A. Valujskikh, R. Fairchild.

    Immunology, Cleveland Clinic, Cleveland, OH.

    Memory T cells with donor-reactivity pose a major barrier to successful allograft transplantation and tolerance induction. Longer cold ischemic storage (CIS) prior to transplantation promotes…
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