2018 American Transplant Congress
Temporal Trends, Predictive Factors, and Regional Differences in Discard of Increased-Risk Kidneys
Surgery, Maine Medical Center, Portland, ME.
Purpose: Public Health Service (PHS) criteria designate certain deceased donors (DD) as entailing increased risk (IR) for disease transmission, and these constitute an expanding proportion…2018 American Transplant Congress
Living Kidney Donation: Impact of Transplant Center Labor, Organization, and Resources
Purpose: Impact of transplant center program size, staffing, and organization on LKD outcomes is unknown. This study describes the labor inputs, organization, and resources available…2018 American Transplant Congress
Financial Burden of Liver Transplant vs Resection for HCC
Surgery, Indiana University, Indianapolis, IN.
There is considerable commentary regarding liver transplant vs resection for the treatment of hepatocellular carcinoma (HCC). While liver transplant provides longer survival when compared to…2018 American Transplant Congress
Donor Derived Transmissions in 2016-2017: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
DTAC, United Network for Organ Sharing, Richmond, VA.
The DTAC evaluates unanticipated potential donor-derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of donor transmission. Reporting policy…2018 American Transplant Congress
Reducing No-Show Rate and Filling Cancelled Appointments: Multi-Faceted Interventions Markedly Reduced Time to Kidney Transplant Evaluation
Piedmont Transplant Institute, Piedmont Atlanta Hospital, Atlanta, GA.
Introduction: Time from referral to appointment for kidney transplant evaluation is an important metric. Demands of dialysis schedules and transportation logistics typically lead to high…2018 American Transplant Congress
Everolimus with Reduced Calcineurin Inhibitor Exposure in De Novo Kidney Transplant Recipients: Efficacy and Safety Outcomes from the TRANSFORM Study
1TRANSFORM Study Group, Livingston; 2Novartis Pharma AG, Basel, Switzerland.
Purpose: Everolimus (EVR)-facilitated calcineurin inhibitor (CNI) reduction regimens help prevent long-term CNI nephrotoxicity in kidney transplant recipients (KTxRs). TRANSFORM (NCT01950819) is the largest study in…2018 American Transplant Congress
Circulating Follicular Helper T Cells (cTfh) in Renal Transplantation: Utility as Rejection Biomarker
Introduction: Antibody (Ab) mediated rejection is responsible for 30-50% of renal graft failures. Follicular helper T cells (Tfh) are required for the differentiation of B…2018 American Transplant Congress
DNA Methylation Age and Differential Patterns of DNA Methylation in Older Compared with Younger Kidney Transplant Recipients
David Geffen School of Medicine at UCLA, Los Angeles, CA.
Introduction: Older transplant recipients experience increased rates of infection and death, but decreased rates of rejection, suggesting a role of immune dysfunction. Analysis of DNA…2018 American Transplant Congress
AT1R Antibody Analysis: High Proportion of Non-Specific Reactivity?
INTRODUCTION:The angiotensin II type 1 receptor (AT1R) is expressed on vascular endothelium. AT1R antibodies (Ab) have been studied to examine their relevance in renal and…2018 American Transplant Congress
Whole-Transcriptome Sequencing to Identify Macaque Immune Gene Variants
Macaque monkeys are critical in transplantation studies, yet macaque genomics lags significantly behind human genomics. While reliable genotyping methods have been developed for some macaque…
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