Am J Transplant, Volume 18, Suppl 3 Archives - Page 200 of 211 - ATC Abstracts

2018 American Transplant Congress
Programmed Cell Death Ligand 1 (PD-L1) Expression is Associated with Subtypes of Post-Transplant Lymphoproliferative Disorders (PTLD)
N. Rodig,¹ G. Pinkus,² G. Ramos Gonzalez,³ T. Agur,¹ O. Weinberg.⁴
¹Pediatrics, Boston Children's Hospital, Boston, MA; ²Pathology, Brigham and Women's Hospital, Boston, MA; ³Surgery, Boston Children's Hospital, Boston, MA; ⁴Pathology, Boston Children's Hospital, Boston, MA.
Introduction: PD-L1 expression on select tumor cells engages the PD-1 receptor on T cells, inhibiting anti-tumor immune responses. PD-L1 has been detected in cases of…
2018 American Transplant Congress
End Stage Renal Disease after Face Transplant
N. Shockcor,¹ B. Buckingham,¹ W. Hassanein,¹ A. Haririan,¹ S. Roberts,² A. Nam,¹ E. Rodriguez,³ S. Bartlett,¹ R. Barth.¹
¹University of Maryland, Baltimore, MD; ²Ochsner Health Center, Covington, LA; ³New York University, New York, NY.
Purpose Renal failure as an outcome of chronic immunosuppression is a known complication of organ transplantation. We report the first case of end stage renal…
2018 American Transplant Congress
Targeted Donor Complement Blockade after Brain-Death Prevents Delayed Graft Function but Not Progression to Antibody-Mediated Rejection in a Non-Human Primate Model of Kidney Allo-Transplantation
J. Danobeitia,¹ T. Zens,¹ L. Zitur,¹ P. Chlebeck,¹ J. Torrealba,³ D. Burguete, E. Van Amersfoort,² A. Relan,² A. D'Alessandro,¹ L. Fernandez.¹
¹Surgery, University of Wisconsin-Madison, Madison, WI; ²Pharming Group N.V, Leiden, Netherlands.
Introduction: Donor brain death (BD) triggers a complement-mediated inflammatory response linked to renal injury which has been associated to delayed graft function (DGF) and the…
2018 American Transplant Congress
modified DFPP Can Eliminate Donor-Reactive IgG Antibody with Preserving Fibrinogen before Kidney Transplantation
D. Iwami,¹ T. Matsumoto,² K. Hotta,¹ M. Ota,² Y. Chiba,² H. Higuchi,¹ N. Shinohara.¹
¹Renal and Genitourinary Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Hokkaido, Japan; ²Medical Engineering Center, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
BACKGROUND: Elimination of preexisting IgG antibodies against donor antigen is an important role before antibody-incompatible (i.e. ABO-incompatible and donor-specific antibody positive) kidney transplantation. Plasma exchange…
2018 American Transplant Congress
A Novel Score for Predicting Mortality and Graft Failure after Kidney Transplant
C. Parsons, F. Shamoun, S. Patel, S. Cha, R. Heilman, M. Keddis.
Mayo Clinic, Scottsdale.
Purpose:To develop a novel score for predicting mortality and graft failure after kidney transplant.Methods:We reviewed a cohort of 783 kidney transplant recipients and analyzed pertinent…
2018 American Transplant Congress
Development and Validation of FLF-Transplant Score to Predict Mortality of Status 1A Candidates
Z. Guo, B. Chen, Q. Zhao, E. Xin, Z. Zhang, L. Wang, X. He, G. Chen.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Orthotopic liver transplantation (OLT) is the definitive treatment for patients with fulminant liver failure (Status 1A). We aimed to develop a prognostic model for prediction…
2018 American Transplant Congress
Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation. A Study of the United Kingdom Transplant Registry
P. Yiannoullou,^1,2 A. Summers,^1,2 C. Fullwood,² Z. Moinuddin,^1,2 I. Shapey,^1,2 H. Khambalia,^1,2 T. Augustine,^1,2 M. Rutter,^1,2 D. van Dellen.^1,2
¹Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom; ²University of Manchester, Manchester, United Kingdom.
BackgroundPatients with type 1 diabetes mellitus (T1DM) and end-stage renal disease (ESRD) suffer increased cardiovascular morbidity and mortality. Simultaneous pancreas and kidney transplantation (SPKT) improves…
2018 American Transplant Congress
Trends and Policy Influences on Multiple Listing Practices for Kidney Transplantation between 2000 and 2017
M. Decoteau,¹ D. Stewart,² A. Toll,² J. Case,¹ C. Marsh.¹
¹Organ Transplantation, Scripps Green Hospital, La Jolla, CA; ²United Network for Organ Sharing, Richmond, VA.
BACKGROUND: Organ allocation policies continually evolve to address long transplant wait times and a limited donor organ pool. Transplant candidates may list at multiple centers…
2018 American Transplant Congress
Donor Reactive Eomesdermin^hiCD8⁺ T Cells Are Significantly Upregulated Early after Transplant in Kidney Transplant Patients without Rejection
A. Perez-Gutierrez,^1,2 D. Metes,¹ S. Hariharan,¹ A. Thomson,¹ M. Ezzelarab.¹
¹Surgery, Thomas Starzl Transplantation Institute, Pittsburgh, PA; ²Surgery, Transplantation Institute, University of Chicago, Chicago, IL.
IntroductionMemory T cell responses play a critical role in the outcome of allo-transplantation. While the role of the T-box transcription factor Eomesodermin (Eomes) in the…
2018 American Transplant Congress
Examples of the Observer Effect in Transplantation- Unintended Consequences of Regulation and Selected Outcome Metrics
A. Rana, M. Kueht, N. Galvan, R. Cotton, C. O'Mahony, J. Goss.
Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Introduction: The influence of an observer on the phenomena being observed is designated as the observer effect. It is our aim to demonstrate that an…