2018 American Transplant Congress
Shikonin Inhibits Th17 Development through Repressing STAT3 Activation
Background: Th17-mediated inflammatory responses are detrimental for allograft acceptance and long-term survival after transplantation. Shikonin is a naphthoquinone pigment isolated from a traditional medicinal herb…2018 American Transplant Congress
Multi-Visceral Transplant in an HIV Positive Recipient – One Year Survival
Surgery, Indiana University School of Medicine, Indianapolis, IN.
Human immunodeficiency virus (HIV) is associated with hypercoagulability and thrombotic events. Highly active anti-retroviral therapy (HAART) has improved long term survival. More patients with HIV…2018 American Transplant Congress
Host Factors and Clinical Spectrum of Adenovirus Infection in Pediatric Solid Organ Transplantation: A Closer Look at the Infant, the Toddler and the Child
Pediatrics, Stanford University, Stanford, CA.
Adenovirus (AdV) is increasingly recognized in solid organ transplants (SOT), with reported mortality exceeding 50%. Characterization of AdV infection in the pediatric SOT population is…2018 American Transplant Congress
T2Candida for Diagnosis of Candidemia in Solid Organ Transplant Recipients
University of Alabama at Birmingham, Birmingham, AL.
Purpose: Candidemia is a critical contributor to morbidity following solid organ transplantation (SOT). The purpose of this study is to evaluate the T2Candida assay (T2)…2018 American Transplant Congress
Analysis of Circulating CD38+/CD138+ Plasma Cells during Development of De Novo Donor Specific Antibody Responses
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Purpose: Donor specific antibodies (DSA) that emerge following transplantation are indicative of allogenic sensitization and a predisposing factor for antibody mediated rejection. Though various methods…2018 American Transplant Congress
Assessing Necroptosis in Brain Dead Kidney Donors: Implications for Predicting Recipient Outcomes
Medicine, University of Alabama at Birmingham, Birmingham, AL.
Introduction: Kidney graft transplant obtained from Brain Dead Donors (BDD) is more frequently associated with development of delayed graft function (DGF) and higher risk of…2018 American Transplant Congress
Targeting Calcium Release-Activated Calcium (CRAC) Channel in Non-Human Primate Kidney Transplantation
[Background] Long-term administration of calcineurin inhibitors (CNIs) successfully controls rejection of transplanted organs. However, the chronic use of these drugs causes organ damage often resulting…2018 American Transplant Congress
Preoperative Antibiotics Treatment Decreases Endoplasmic Reticulum Stress and Protects Liver Transplant from Ischemia-Reperfusion Injury
Department of Surgery, The Dumont-UCLA Transplant Center, Los Angeles, CA.
Ischemia-reperfusion injury (IRI) represents a major risk factor of graft dysfunction in liver transplantation (LT). We have reported a critical role of endoplasmic reticulum (ER)…2018 American Transplant Congress
Donor Specific Antibodies Increase the Risk of Preeclampsia in Pregnant Kidney Transplant Recipients
Weill Cornell-New York Presbyterian, NY, NY.
Kidney transplant recipients are at an increased risk for pregnancy-associated complications including preeclampsia (PEC). Endothelial injury in the placenta is a hallmark of PEC. The…2018 American Transplant Congress
Metabolic Acidosis after Kidney Transplantation: Prevalence, Risk Factors and Graft Outcome in a French Cohort
Nephrology, University Hospital of Montpellier, Montpellier, France.
Background: Metabolic acidosis (MA) lead to several complications in more advanced stages of chronic kidney diseases (CKD) and promotes CKD progression. Acidosis is a common…
American Transplant Congress abstracts