2018 American Transplant Congress
Alveolar Macrophages Derived from MCMV Latently Infected Donors Drives the Viral Reactivation and Dissemination Following the Orthotopic Left Lung Transplantation in Mice
Background: The incidence of cytomegalovirus (CMV) disease is higher in lung transplants, than in other SOT recipients, especially in high-risk D+/R- recipients. Using a murine…2018 American Transplant Congress
Mitochondrial Autophagy Proteins Bnip3 and Nix Maintain Memory B Cell Survival
Despite the use of immunosuppressive drugs, allograft rejection remains a major hurdle for the long-term success of organ transplants. Burgeoning evidence implicates memory B cells…2018 American Transplant Congress
The First Series of Ischemia-Free Liver Transplantation in Human
BACKGROUND&AIMS: Ischemia and reperfusion injury (IRI) is known as an inevitable event leading to early and late graft failure. We have performed the first case…2018 American Transplant Congress
Thymoglobulin Induction in HIV Positive Kidney Transplant Recipients: Report on Transplant and HIV Outcomes
Piedmont Transplant Institute, Piedmont Atlanta Hospital, Atlanta, GA.
Introduction: Kidney transplant outcomes in HIV positive recipients are similar to HIV negative recipients. However, high published rates of acute rejection are a challenge. There…2018 American Transplant Congress
Quality of Social Support Network and Access to Transplant: What Matters?
Recovery after kidney transplant (KT) requires adequate social support. Caregivers are asked to attend transplant evaluation and complete a caregiver contract. Little is known about…2018 American Transplant Congress
Long-Term Follow-Up of Patients with Primary Sclerosing Cholangitis Undergoing Liver Transplantation with Duct-to-Duct Biliary Reconstruction
Transplant Surgery, Cleveland Clinic, Cleveland, OH.
Background:Reconstruction of biliary drainage after liver transplantation (LTx) in patients with primary sclerosing cholangitis (PSC) has been a matter of controversy. Over the recent years,…2018 American Transplant Congress
T-Cell Expression of C5a Receptor 2 Augments Murine Regulatory T Cell Generation and Regulatory-T-Cell-Dependent Cardiac Allograft Survival
C5aR2 (C5L2/gp77) is a transmembrane receptor that binds C5a but lacks motifs needed to induce G-protein coupled signal transduction. C5aR2 modulates various inflammatory diseases in…2018 American Transplant Congress
Induction Agents and Post-Transplant Malignancies in Kidney Transplants: An Examination of Outcomes at a Large Volume Center over 20 Years
Division of Transplant Surgery, University of Wisconsin, Madison, WI.
Introduction: Induction agents have a profound effect on the immune milieu at the time of kidney transplantation. However, evaluation of their long-term effects on graft…2018 American Transplant Congress
RNA Expression Profiling of Renal Allografts in a Non-Human Primate Identifies Inflammation as a Risk Factor in Chronic Antibody Mediated Rejection
IntroductionChronic alloantibody mediated rejection (CAMR) is a major risk factor in renal allografts. Some inflammation is commonly identified within CAMR, though mostly low grade, and…2018 American Transplant Congress
The Mark of Zorro: IL35-Coated Exosomes Cross-Dress and Exhaust Recipient T & B Cells during Transplant Tolerance
The folk-hero "Zorro" left his mark on by a sword-slashed "Z". In transplant recipients, rare Tregs also leave a mark on their conventional T &…
American Transplant Congress abstracts