ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    A Pre-Transplant Blood-Based Lipid Signature for Prediction of Antibody-Mediated Rejection in Kidney Transplant Patients

    G. Gupta, S. Bobba, D. Contaifer, P. Kimball, A. King, D. Kumar, M. Levy, J. Stern, D. Wijesinghe.

    Virginia Commonwealth University, Richmond.

    BACKGROUNDThere is a lack of biomarkers for pre-kidney transplant immune risk stratification to avoid over- or under-immunosuppression. Since the circulating lipidome is integrally involved in…
  • 2018 American Transplant Congress

    Comparison of Bortezomib in Addition to Rituximab Based Treatment of Acute Antibody Mediated Rejection in Kidney Transplantation

    A. Mattiazzi,1,2 J. Pagan,1,2 A. Arunachalam,1 I. De la Cruz Alcantara,1 J. Revollo,2 A. Centeno,2 A. Valdes,1,2 G. Guerra.1,2

    1Nephrology & Hypertension, University of Miami, Miami, FL; 2Miami Transplant Institute, Jackson Memorial Hospital, Miami, FL.

    Purpose:The optimal treatment strategy of acute antibody mediated rejection (AMR) in renal allograft recipients remains undefined. The aim of our study was to compare the…
  • 2018 American Transplant Congress

    The Treatment of Antibody-Mediated Rejection in Kidney Transplantation: An Updated Systematic Review and Meta-Analysis

    S. Wan,1,2 T. Ying,1,2 K. Wyburn,1,2 D. Roberts,3,4 M. Wyld,1,2 S. Chadban.1,2

    1Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; 2Sydney Medical School, University of Sydney, Sydney, Australia; 3Department of Renal Medicine, Canberra Hospital and Health Services, Canberra, Australia; 4Medical School, Australian National University, Canberra, Australia.

    Introduction: Current treatment strategies for antibody-mediated rejection (AMR) in kidney transplantation are based on low quality data from a small number of controlled trials. Novel…
  • 2018 American Transplant Congress

    Immunologic Impact of Tocilizumab Treatment in Kidney Transplant Recipients with Allograft Inflammation

    J. Leung, S. Chandran, F. Vincenti, Q. Tang.

    UCSF, San Francisco.

    Background: Proinflammatory cytokine IL-6 increases effector/memory T-cells, induces Th17 cells and prevents the induction of Tregs. IL-6 expression in kidney biopsies is elevated during acute…
  • 2018 American Transplant Congress

    Immuoadsorption-Based Desensitization in Highly Sensitized Patients Awaiting Deceased Donor Kidney Transplantation.

    C. Bureau, P. Galichon, Y. Luque, N. Ouali, E. Rondeau, C. Rafat.

    Urgences Néphrologiques et Transplantation Rénale, Tenon Hospital, APHP, Paris, France.

    An estimated 30% of patients on the waiting list are deemed highly sensitized due to preexisting anti-HLA antibodies often irrevocably precluding kidney transplantation (KT). Immunoadsorption…
  • 2018 American Transplant Congress

    The Effects of Pre-Transplant Pyuria of the Deceased Donor on Post-Transplant Urinary Tract Infections in the Case of Gender Mismatch Transplantation

    Y. Kim,1 S. Park.2

    1Nephrology, Haeundae Paik Hospital, Busan, Korea; 2Nephrology, Busan Paik Hospital, Busan, Korea.

    Introduction: Renal transplantation is one of the best treatment options in patients with end-stage renal diseas. It is reported that kidney transplantation using organs from…
  • 2018 American Transplant Congress

    Transplant Tourism and Invasive Fungal Infection

    F. Al Ismaili,1 A. Metry,3 M. Al Riyami,5 F. Khamis,6 F. Shaheen,7 A. Hola,4 I. Al Salmi.2

    1The Renal Medicine, The Royal Hospital, Muscat, Oman; 2The Renal Medicine, The Royal Hospital, Muscat, Oman; 3The Renal Medicine, The Royal Hospital, Muscat, Oman; 4Histopathology, SQUH, Muscat, Oman; 5Infectious Diseases, The Royal Hospital, Muscat, Oman; 6SCOT, SCOT, RIyadh, Saudi Arabia; 7The Renal Medicine, The Royal Hospital, Muscat, Oman; 8The Renal Medicine, The Royal Hospital, Muscat, Oman.

    Deceased and live-related Renal transplant (RTX) are widespread approved methods throughout the world. In-addition, commercial-RTX has gained an access at certain places driven by financial…
  • 2018 American Transplant Congress

    Metabolic Complications 10-Years after Kidney Transplant

    E. Lorenz, F. Cosio, M. Stegall.

    Mayo Clinic, Rochester.

    Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…
  • 2018 American Transplant Congress

    Direct Oral Anticoagulation Use in Kidney Transplant Recipients

    S. Shaikh,1 M. Samaniego,2 J. Park.2

    1MedStar Georgetown University Hospital, Washington DC; 2Michigan Medicine, Ann Arbor, MI.

    Objective: There is a lack of high-level evidence identifying meaningful outcomes with direct oral anticoagulants (DOACs) in kidney transplant recipients. The primary objective of this…
  • 2018 American Transplant Congress

    Donor TM6SF2 rs58542926 Genotype is a Risk Factor for Liver Graft Steatosis

    I. Mikova,1 M. Neroldova,2 J. Hubacek,2 D. Dlouha,2 L. Kolesar,3 M. Jirsa,2 E. Honsova,4 E. Sticova,4 V. Lanska,5 J. Spicak,1 P. Trunecka.1

    1Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 3Department of Clinical and Transplant Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 4Department of Clinical and Transplant Pathology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 5Medical Statistics Unit, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

    Background & Aims: The rs58542926 c.449C>T (p.E167K) polymorphism in TM6SF2 (transmembrane 6 superfamily member 2) is one of genetic factors predisposing to nonalcoholic fatty liver…
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