Am J Transplant, Volume 18, Suppl 3 Archives - Page 191 of 211 - ATC Abstracts

2018 American Transplant Congress
Living Donor Renal Transplantation in Adult Renal Transplant Recipients Varies Markedly across UNOS Networks
A. Brar,¹ A. Gruessner,¹ M. Salifu,¹ R. Gruessner,² N. Sumrani,² D. John,² F. Tedla.¹
¹Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; ²Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY.
Background: Outcome after living donor kidney transplantation (LD) is significantly better than after deceased donor transplantation (DD). Disparities in access to living donor renal transplantation…
2018 American Transplant Congress
Identifying Patients at Risk of Mortality and Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation Using the Pre-Transplant QRISK2 Score
P. Yiannoullou,^1,2 S. Goh,² H. Khambalia,^1,2 Z. Moinuddin,^1,2 A. Summers,^1,2 I. Shapey,^1,2 C. Fullwood,² T. Augustine,^1,2 M. Rutter,^1,2 D. van Dellen.^1,2
¹Transplant, Manchester University Foundation NHS Trust, Manchester, United Kingdom; ²University of Manchester, Manchester, United Kingdom.
Introduction Patients with type 1 diabetes mellitus and renal failure have increased mortality risk. Simultaneous Pancreas and Kidney transplantation (SPKT) provides survival benefit, but premature…
2018 American Transplant Congress
Impact of a Steroid Free Immunosuppressive Regimen on Patient and Graft Outcomes in Pancreas Transplant Recipients
M. Cote,¹ C. Rogers,¹ K. Khwaja,² A. Evenson,² M. Pavlakis,² K. Richards.¹
¹Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA; ²Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA.
Steroids have been an important component of maintenance immunosuppression in solid organ transplant, but their adverse effect profile has led to the development of steroid…
2018 American Transplant Congress
Pregnancies in Female Pancreas Transplant Alone Recipients
P. Patel,¹ D. Kliniewski,² L. Coscia,² D. Armenti,² S. Constantinescu,^2,3 M. Moritz.^1,2,4
¹Surgery, Lehigh Valley Health Network, Allentown, PA; ²Transplant Pregnancy Registry International, Gift of Life Institute, Philadelphia; ³Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA; ⁴Surgery, Morsani College of Medicine, Tampa, FL.
This is the first series report of pregnancies after pancreas transplant alone (PTA). Data were collected by the Transplant Pregnancy Registry International (TPR) via questionnaires,…
2018 American Transplant Congress
Telemedicine Implementation in Organ Transplantation at a Metropolitan Academic Medical Center
D. Tsapepas, H. Li, D. Kohlberg, B. Watts, J. Monteiro, A. Monteiro, N. Jandovitz.
Columbia University / NewYork-Presbyterian Hospital, New York.
Transplant patients represent a complex patient population for which telemedicine may enhance patient access to the healthcare team, patient engagement, patient satisfaction and improved outcomes…
2018 American Transplant Congress
A Novel Conditioning Approach to Establish Chimerism Using Manipulation of JAK-STAT Pathways
H. Xu, A. Merchak, L. Kahn, A. Chhabra, Y. Wen, Y. Huang, S. Ildstad.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
Hematopoietic chimerism establishes donor-specific tolerance to solid organ allografts. Targeting recipient immune cells (T, NK cells and macrophages) can effectively reduce the dose of total…
2018 American Transplant Congress
M-CSF and TNF-α Induce Human MDSCs That Attenuate GVHD
F. Han, C. Ding, Y. Zhao, P. Tian.
Department of Kidney Transplantation, Hospital of Nephropathy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Myeloid-derived suppressor cells (MDSCs) negatively regulate immune response and participate in the induction of prolonged allograft survival in animal models. Human MDSC therapy may be…
2018 American Transplant Congress
Effect of Erythropoietin on Cardiac Allograft Survival in Non-Human Primates
J. O.,¹ K. Robinson,¹ W. Sommer,¹ K. Pruner,¹ J. Paster,¹ M. Hanekamp,¹ A. Dehnadi,¹ I. Rosales,¹ R. Smith,¹ P. Cravedi,² P. Heeger,² G. Benichou,¹ J. Madsen.¹
¹MGH, Boston; ²Icahn School of Medicine at Mount Sinai, New York.
Purpose: Tolerance of cardiac allografts has been achieved in cynomolgus monkeys for the first time via mixed hematopoietic chimerism and donor kidney co-transplantation, but the…
2018 American Transplant Congress
Post-Hoc Analysis of Everolimus Trough Levels around the Onset of Related Adverse Events and Treatment Discontinuation in De Novo Kidney Transplant Recipients from the US92 Study
F. Shihab,¹ Y. Qazi,¹ V. Peddi,¹ D. Shaffer,¹ K. McCague,² D. Patel,² S. Mulgaonkar.¹
¹US92 Study Group, Salt Lake City; ²Novartis Pharmaceutical Corporation, East Hanover.
Purpose: Around 30%-50% of kidney transplant recipients (KTR) on sirolimus discontinue treatment due to drug-related adverse events (AE) and ~23% on everolimus (EVR) discontinue treatment…
2018 American Transplant Congress
Comparison of Continuous Normothermic Ex Vivo Kidney Perfusion to Hypothermic Preservation Methods in Pig Kidneys Donated after Cardiac Death
M. Hamar,^1,2 P. Urbanellis,¹ D. Kollmann,¹ I. Linares,¹ M. Kaths,¹ D. Bagli,³ A. Konvalinka,⁴ I. Mucsi,¹ A. Ghanekar,¹ L. Robinson,² M. Selzner.¹
¹Multi Organ Transplant Program, TGH, Toronto, ON, Canada; ²Division of Nephrology, The Hospital of Sick Children, Toronto, ON, Canada; ³Dept. of Surgery (Urology) & Physiology, The Hospital of Sick Children, Toronto, ON, Canada; ⁴Dept. of Medicine and Institute of Medical Science, UHN and Univ. of Toronto, Toronto, ON, Canada.
Background: Strategies to decrease preservation-related injury in renal grafts donated after circulatory death urgently needed. This highlights the importance of direct comparison of dynamic preservation…