ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Gender Disparities in Need for Dialysis, Access to the Renal Transplant Waitlist and Renal Transplant Survival

    B. Schmidt,1 J. Epping,2 C. Falk,4 S. Geyer,2 A. Melk.3

    1Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; 2Medical Sociology, Hannover Medical School, Hannover, Germany; 3Pediatric Nephrology, Hannover Medical School, Hannover, Germany; 4Institute of Transplantation Immunology, Hannover Medical School, Hannover, Germany.

    A patient with chronic kidney disease undergoes several transition phases, such as start of dialysis, the placement on the transplant waiting list and finally renal…
  • 2018 American Transplant Congress

    Pancreas Outcomes between Living and Deceased Kidney Donor Recipients in Pancreas after Kidney Transplantation

    P. Ventura-Aguiar,1 J. Ferrer,2 I. Revuelta,1 D. Paredes,3 E. De-Sousa,1 J. Rovira,4 E. Esmatjes,5 J. Garcia-Valdecasas,2 F. Oppenheimer,1 F. Diekmann,1 M. Ricart.1

    1Nephrology and Kidney Transplantation Department, Hospital Clinic, Barcelona, Spain; 2Hepatobiliopancreatic and Liver Transplant Department, Hospital Clinic, Barcelona, Spain; 3Organ Transplantation Coordination Department, Hospital Clinic, Barcelona, Spain; 4Laboratori Experimental de Nefrologia I Trasplantament (LENIT), IDIBAPS, Barcelona, Spain; 5Diabetes Unit, Department of Endocrinology and Nutrition, Hospital Clinic, Barcelona, Spain.

    Pancreas outcomes in pancreas after kidney transplantation have been reported as being inferior to those from simultaneous pancreas-pancreas (SPK). The influence of kidney donor (living-…
  • 2018 American Transplant Congress

    Estimation of Beta Cell Function after Total Pancreatectomy with Islet Autotransplantation Using Single Fasting Blood Sample Based Indices and Modified Igls Score.

    J. Gołębiewska,1 P. Bachul,2 L. Basto,2 M. Kijek,2 N. Fillman,2 K. Cieply,2 K. Golab,2 L. Wang,2 M. Tibudan,2 C. Thomas,3 A. Dębska-Ślizień,1 J. Fung,2 P. Witkowski.2

    1Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland; 2Surgery, University of Chicago, Chicago; 3Medicine, University of Chicago, Chicago.

    Background: For precise yet logistically feasible evaluation of beta-cell function after total pancreatectomy with islet autotransplantation (TPIAT), we investigated the utility of indices using only…
  • 2018 American Transplant Congress

    Virtual Encounters: Robust Methods to Manage Your Active Waitlist

    K. Curry, S. Zimmerman, D. Cassidy, S. Gray, V. Rao, V. Rohan, N. Pilch, A. Milling, L. Curry.

    Transplant, MUSC, Charleston, SC.

    Introduction: The ability to ensure all patients are transplant ready and do not have outstanding issues that would diminish post-transplant outcomes is challenging with an…
  • 2018 American Transplant Congress

    The Providers Can't Let Go! An Analysis of an RN Driven Tacrolimus Dose Adjustment Protocol

    Z. Elmaasarani, C. Mardis, L. Gylten, J. Fleming, H. Meadows, N. Patel, C. Perez, D. Taber, V. Rao, V. Rohan, P. Baliga, D. Dubay, N. Pilch.

    MUSC, Charleston.

    Introduction: Tacrolimus (FK) dose adjustment is frequently performed by non-MD staff. Standard protocols to evaluate the ability of non-providers to maintain pts within a goal…
  • 2018 American Transplant Congress

    Myeloid Derived Suppressor Cells Are Induced after Transplantation and Home to the Transplanted Kidney

    Y. Lee, E. Davila, J. Bromberg, J. Scalea.

    Surgery and Immunology, University of Maryland, Baltimore, MD.

    BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are a naturally occurring, heterogeneous population of highly immunosuppressive cells which expand in response to inflammatory conditions such as cancer.…
  • 2018 American Transplant Congress

    Renal Allograft Molecular Pathways Associated with Tolerance Induction in Renal Transplantation

    L. Gallon,1 J. Mathew,1 S. Bontha,2 C. Dumur,2 P. Dalal,1 L. Nadimpalli,1 D. Maluf,2 A. Shetty,1 S. Ildstad,3 J. Leventhal,1 V. Mas.2

    1Department of Medicine-Nephrology, Northwestern University, Chicago, IL; 2Department of Surgery, University of Virginia, Charlottesville, VA; 3Departments of Surgery, Physiology and Immunology, University of Louisville, Louisville, KY.

    Background: Chronic exposure to immunosuppressive agents for organ transplant results in graft nephrotoxicity, infections and malignancies We have established durable immune tolerance in mismatched related…
  • 2018 American Transplant Congress

    Loss of HIF-1α in CD4 T Cell Improve Outcome of Mouse Vascularized Osteomyocutaneous Allotransplantation under Costimulation Blockade

    C-.H. Lin,1,2 M. Anggelia,1,2 H. Yang,3 W. Chuang,4 H. Cheng,1 F-.C. Wei,1,2 G. Brandacher.5

    1PRS, Center for VCA, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 2Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan; 3Nephrology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 5PRS, Johns Hopkins University School of Medicine, Baltimore, MD.

    Background: Allograft survival depends on the balance of effector T cells (Teff) and regulatory T cells (Tregs). Previous study suggested that the balance is controlled…
  • 2018 American Transplant Congress

    Melatonin Prolongs Heart Allograft Survival by Induction of Foxp3+ Regulatory T Cells

    L. Liu, Q. Su, Y. Xiong, Z. Bi, H. Huang, Y. Peng, C. Wang.

    The First Affiliated Hospital of Sun Yet-sen University, Guangzhou, China.

    Objective: This study was aimed to investigate the effect of melatonin on heart allograft survival and explore the underlying mechanism. Methods and Results: Balb/c and…
  • 2018 American Transplant Congress

    New Sensitive Markers for Early Diagnosis of Transplant Glomerulopathy in Kidney Recipients

    Y-.C. Xu-Dubois, K. Louis, C. Jouanneau, D. Buob, N. Ouali, A. Hertig, E. Rondeau.

    U1155, INSERM, Paris, France; Urgences Néphrologiques & Transplantation Rénale, APHP, Hôpital Tenon, Paris, France; Santé Publique, APHP, Hôpital Tenon, Paris, France; Sorbonne Universités, UPMC Université Paris 6, Paris, France.

    Chronic antibody mediated rejection (ABMR) with Transplant glomerulopathy (TG) remains a major contributor of renal graft loss in the long term. New sensitive markers are…
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