2018 American Transplant Congress
Reliability of Bronchiolitis Obliterans Syndrome Reporting to the OPTN
Background: Chronic rejection of the lung allograft is traditionally classified as bronchiolitis obliterans syndrome (BOS) diagnosed by obstructive airway physiology. The OPTN requires the reporting…2018 American Transplant Congress
Evaluation of Survival and Maintenance Immunosuppression in Elderly Lung Transplant Recipients
Background: Lung transplantation in the elderly is controversial given increased risks and the optimal immunosuppression regimen is not fully understood.Methods: A retrospective cohort study was…2018 American Transplant Congress
TLR2 with TCR Signaling Mobilizes Treg Lymphatic Migration
Background: Regulatory T cells (Treg) express high levels of lymphotoxin (LT) and bind the LT receptor (LTβR) on lymphatic endothelial cells (LEC). This receptor-ligand interaction…2018 American Transplant Congress
How the Spouses (Husbands) of Living Kidney Donors View Kidney Donation: A Grounded Theory Study
Division of Nursing, University of Mount Olive, Mount Olive, NC.
The purpose of this study was to explore the question: What is the process of experiencing living kidney transplant by the spouse of a living…2018 American Transplant Congress
Efficacy of Two Valganciclovir Dosing Strategies in Intermediate and High-Risk Liver Transplant Recipients
Purpose: There is interest in reduced dosing and duration of valganciclovir (VGCV) for cytomegalovirus (CMV) prophylaxis in liver transplant (LT) recipients to minimize side effects…2018 American Transplant Congress
In Vitro Evaluation of Antibiotic Persistence in Pseudomonas aeruginosa and Staphylococcus aureus Isolates from Cystic Fibrosis Patients
UW Hospital & Clinics, Madison; UW School of Pharmacy, Madison.
Purpose: The mechanisms of antibiotic persistence in immunosuppressed populations are not fully understood. Patients with cystic fibrosis (CF), both the pre-transplant and post-transplant phase often…2018 American Transplant Congress
Multi-Targeting Desensitization Therapy Alters Peripheral B-Cell Homeostasis and Suppresses Recall Alloantibody Responses
CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Purpose: Occurring of donor specific antibodies (DSA) is injurious to organ transplant. Development of immunotherapies to suppress DSA, therefore, has been one of the strategic…2018 American Transplant Congress
Pharmacologic Donor Management Influences Liver Transplant Graft Survival and Transplant Admission Length of Stay: An Update
In liver transplantation, donor management is an area that can be modified to improve survival and lower cost. We reviewed the UNOS Standard Transplant Analysis…2018 American Transplant Congress
Characterization of Mesenchymal Stem Cell Phenotype and Its Immunomodulatory Effects during Allo-Specific T Cell Immune-Responses
Department of Surgery, Duke University Medical Center, Durham, NC.
Mesenchymal stem cells (MSCs) have been suggested play an important role in modulating cell-mediated immunity. In the setting of transplantation, allogeneic MSCs could mediate suppressive…2018 American Transplant Congress
The Impact of Pre-Operative Opioid Use on Delayed Graft Function in Adult Kidney Transplant Recipients
Background and Objectives: Opioid use is associated with AKI and ATN through both direct and indirect mechanisms, including alterations in the autonomic nervous system, the…
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