Am J Transplant, Volume 18, Suppl 3 Archives - Page 187 of 211 - ATC Abstracts

2018 American Transplant Congress
Incisional Hernia Repair after Abdominal Solid Organ Transplant and Living Kidney Donation: A Single Institution Experience
C. Kensinger,¹ S. Phillips,² D. Hale,² D. Shaffer,² B. Poulose,² R. Baucom.³
¹University of Wisconsin, Madision; ²Vanderbilt Medical Center, Nashville; ³Baylor University Medical Center, Dallas.
Purpose: The incidence of incisional hernias (IH) requiring operative repair in live kidney donors and abdominal transplant recipients is not well-defined. Therefore, we examined the…
2018 American Transplant Congress
Brincidofovir Was Used to Successfully Treat Adenovirus Infections in Solid Organ Transplant Recipients and Other Immunocompromised Patients
D. Florescu,¹ M. Grimley,² G. Papanicolaou,³ V. Prasad,⁴ E. Vainorius,⁵ G. Chittick,⁵ T. Brundage,⁵ G. Nichols.⁵
¹Univ Nebraska Med Center, Omaha; ²Cincinnati Children's Hosp Center, Cincinnati; ³Memorial-Sloan Kettering Cancer Center, New York; ⁴Pediatric BMT, Duke Univ Med Center, Durham, NC; ⁵Chimerix, Inc., Durham.
Background: Adenovirus (AdV) infections cause significant morbidity and mortality in immunocompromised patients. Brincidofovir (BCV) is an investigational antiviral drug with high in vitro potency against…
2018 American Transplant Congress
Identifying the Specific Causes of Kidney Allograft Loss: A Population Based Study
C. Loheac, O. Aubert, D. VIglietti, N. Kamar, M. Delahousse, C. Lefaucheur, A. Loupy.
Paris Translational Research Center for Organ Transplantation, Paris, France.
Understanding the specific causes of kidney allograft loss is mandatory to improve the longevity of kidney allografts. However, the current literature is limited by the…
2018 American Transplant Congress
Mortality and ESRD in Older Live Kidney Donors with Hypertension
F. Al Ammary,¹ X. Luo,¹ A. Muzaale,¹ A. Massie,¹ D. Brennan,¹ A. Wiseman,² J. Snyder,³ D. Segev.¹
¹Johns Hopkins, Baltimore; ²University of Colorado, Aurora; ³SRTR, Minneapolis.
Hypertension in otherwise healthy screened older kidney donor candidates is viewed as relatively benign, yet the long-term outcome of older donors with hypertension is unclear.…
2018 American Transplant Congress
Use of Surgically Placed Transversus Abdominis Plane (TAP) Block Catheter with Local Anesthetic Infusion in Renal Transplantation
M. Dib,¹ S. Borden,² T. Schell,¹ P. Stahler,¹ T. Al-Qaoud,¹ E. Martinez,¹ E. Grodstein,¹ A. D'Alessandro,¹ J. Odorico,¹ L. Fernandez,¹ J. Mezrich,¹ R. Redfield,¹ D. Foley,¹ D. Al-Adra,¹ D. Kaufman.¹
¹Surgery, University of Wisconsin-Madison, Madison, WI; ²Anesthesia, University of Wisconsin-Madison, Madison, WI.
BackgroundRenal transplant recipients have limitations in pain management, given the nephrotoxicity of NSAIDS and contraindications to regional neuroaxial techniques. Although opioids are widely used post-transplant,…
2018 American Transplant Congress
T Cell Exhaustion Contributes to Operational Tolerance of Liver Allografts in Pediatric Liver Transplant Recipients
B. Ramaswami,¹ M. Marrari,² O. Yoshida,⁵ X. Guo,³ W. Hoffman,³ C. Bentlejewski,² D. Metes,¹ A. Demetris,^1,2 A. Zeevi,² A. Thomson,¹ G. Mazariegos,⁴ G. Chalasani.^1,3
¹Surgery, Starzl Transplantation Institute, Pittsburgh, PA; ²Pathology, University of Pittsburgh, Pittsburgh, PA; ³Medicine, University of Pittsburgh, Pittsburgh, PA; ⁴Children's Hospital, University of Pittsburgh, Pittsburgh, PA; ⁵Gastroenterology, Ehime University Graduate School of Medicine, Toon-shi, Ehime-ken, Japan.
Operational tolerance in the absence of immunosuppression can be successfully attained in pediatric liver transplant recipients. Although DSA are observed in a proportion of operationally…
2018 American Transplant Congress
Medication Adherence: Does Where You Live Matter?
S. Wadhwani,¹ S. Taylor,¹ C. Brokamp,¹ W. Guo,¹ E. Shemesh,² J. Bucuvalas.¹
¹Cincinnati Children's Hospital Medical Center, Cincinnati; ²Mount Sinai School of Medicine, New York.
Background & Objectives: Medication non-adherence remains problematic in pediatric liver transplant (LT)[mdash]estimates suggest that up to 53% of adolescents are non-adherent. We leveraged data from…
2018 American Transplant Congress
Transplantation Tolerance Prevents CMV Reactivation and Preserves Kidney Allograft Function in a D+/R- Transplant Setting
A. Dangi,¹ J-.J. Wang,² M. Burnette,¹ Z. Zhang,² X. Luo.^1,2
¹Division of Nephrology and Hypertension, Department of Medicine, Northwestern University, Chicago, IL; ²Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL.
Background: Immune responses to cytomegalovirus (CMV) infection may precipitate acute/chronic graft rejection in immunocompromised transplant recipients. CMV infection can be primary or its reactivation from…
2018 American Transplant Congress
Upregulated IL-33 in Heart Transplants Modulates Local Myeloid Populations to Protect against Chronic Allograft Rejection
Z. Zhang,¹ Q. Liu,¹ G. Hussey,² J. Dziki,² L. Mathews,¹ H. Dai,¹ G. Dwyer,^1,3 A. Lucas,¹ M. Oberbarnscheidt,¹ S. Badylak,² H. Turnquist.^1,3
¹University of Pittsburgh, Starzl Transplant Institute, Pittsburgh, PA; ²University of Pittsburgh, McGowan Institute for Regenerative Medicine, Pittsburgh, PA; ³Immunology, University of Pittsburgh, Pittsburgh, PA.
Purpose: Interleukin-33 (IL-33) is an “alarmin”, or a self-derived molecule that triggers pleotropic immune responses after release from damaged tissue. Yet, how IL-33 shapes alloresponses…
2018 American Transplant Congress
Multi-Organ (M-O) Prioritization of Kidneys: ? Time for Policy Modification
M. Aeder, N. Turgeon.
Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH; Surgery, Emory University, Atlanta, GA.
The revised Kidney Allocation System (KAS) has been operational for 3 years. The bolus effects seen early following the introduction have abated and a steady…