Am J Transplant, Volume 18, Suppl 3 Archives - Page 18 of 211 - ATC Abstracts

2018 American Transplant Congress
Prolongation of Skin Allograft Survival through Dietary Supplementation of Ayrl Hydrocarbon Receptor Ligands
A. Afrazi, L. Owens, J. Fechner, C. O'Driscoll, J. Mezrich.
Transplant Surgery, University of Wisconsin, Madison, WI.
The Aryl Hydrocarbon Receptor (AHR) is a cytosolic transcription factor with numerous endogenous and xenobiotic ligands playing a key role in a number of cellular…
2018 American Transplant Congress
Donor T Cells Undermine the Graft-Protective Effect of DST Plus Anti-CD154
M. Iglesias, M. Chicco, W. Lee, G. Brandacher, G. Raimondi.
Plastic Surgery, Johns Hopkins University, Baltimore, MD.
Costimulation blockade (CoB) regimens are a promising immunomodulatory strategy to prevent transplant rejection. However, their efficacy is affected by multiple factors, including still unknown ones.…
2018 American Transplant Congress
Thymic Irradiation as a Maneuver for Repertoire Exchange in Costimulatory-Blockade-Based Immunotherapy
M. Mulvihill,¹ B. Ezekian,¹ Q. Gao,¹ K. Samy,¹ R. Davis,¹ F. Leopardi,¹ W. Giles,² F-.F. Yin,² C. Willett,² B. Collins,¹ A. Kirk.¹
¹Department of Surgery, Duke University, Durham, NC; ²Department of Radiation Oncology, Duke University, Durham, NC.
Background All successful, prospective clinical tolerance-induction strategies have employed thymic irradiation to achieve chimerism. However, evidence suggests durable chimerism is not required to attain tolerance.…
2018 American Transplant Congress
Human Endothelial-Like Cells Transdifferentiated from Peripheral CD14⁺ Monocytes Inhibit T Cells in Response to Allo-Stimulation
Y. Tanaka, H. Ohdan.
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
We have previously demonstrated that the endothelial cells located in immune-privilege sites, such as livers, suppress T-cells in response to both of direct and indirect…
2018 American Transplant Congress
Heart Transplant across Low or Moderate Level Donor-Specific Antibodies Have Acceptable Outcome
M. Olymbios, J. Patel, R. Levine, S. Dimbil, M. Kittleson, M. Rafiei, X. Zhang, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: The presence of pre-transplant donor specific antibodies (DSA) can reduce the likelihood of a patient (pt) obtaining a compatible donor heart. The proportion of…
2018 American Transplant Congress
Pre-Transplant Memory Patients Even without Detected Antibody Are at Rejection Risk in the First-Year after Heart Transplantation
J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Patients (pts) with prior transplants, blood transfusions, and pregnancies awaiting heart transplantation (HTx) have potential to develop circulating anti-HLA antibodies (HLA Abs). Pts at…
2018 American Transplant Congress
Left Ventricular Assist Devices Complicated by Gastrointestinal Bleeding and Outcomes on Transplant
L. Aurora, O. Sadiq, H. Nemeh, C. Williams.
Internal Medicine, Cardiac Surgery, Cardiology, Henry Ford Hospital, Detroit.
Left Ventricular Assist Devices (LVAD) are becoming the standard of care in advanced heart failure patients. However, despite ongoing advances in this technology, there remains…
2018 American Transplant Congress
The Kidney Allocation System from the Perspective of a Small Program in a Donor Service Area
K. Brown,² S. Hill,² L. Lipscomb,² A. Jones,² S. Hanna,² J. Africa.¹
¹Glickman Institute, Cleveland Clinic, Cleveland, OH; ²Urology and Renal Transplant, Charleston Area Medical Center, Charleston, WV.
This study investigated the impact of the new kidney allocation system (KAS) on a small transplant program (SP) when compared with the 3 other centers…
2018 American Transplant Congress
Exploring the Impact of Recipient Age with Kidney Donor Risk Index and Estimated Glomerular Filtration Rate at One Year Following Kidney Transplant
S. Chan,^1,2,3 M. Chatfield,⁴ K. Baboolal.^2,3
¹Australian and New Zealand Dialysis and Transplant Registry, Adelaide, South Australia, Australia; ²Kidney Health Service, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; ³Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia; ⁴Statistics Unit, Queensland Institute of Medical Research, Brisbane, Queensland, Australia.
Background: Various kidney donor risk indexes (KDRI) have been developed to predict graft survival with various combinations of donor and recipient characteristics. The aim of…
2018 American Transplant Congress
Improving Participation in Non-A1/Non-A1B to B Deceased Donor Program Post Kidney Allocation System (KAS)- A Single Center Experience
H. Khamash, J. Adamski, R. Heilman, A. Mathur, A. Moss, A. Kumar, Q. Lu, K. Reddy.
Mayo Clinic Arizona, Phoenix.
Blood type B kidney transplant candidates have a longer wait time on the deceased donor list, an average of 6 years compared to 3 years…