ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Procurement Travel Safety: Current Practices, Accident Frequency, Perceptions of Safety and Means to Reduce Risk

    A. Schenk, A. Adams, R. Lynch.

    Emory Transplant Center, Emory University, Atlanta, GA.

    Transplant procurement teams travel extensively. Though considered hazardous, little data on the necessity and risks of this travel exist. We conducted a survey of ASTS…
  • 2018 American Transplant Congress

    Organ Transplant Abuse in China (2): Continued Growth after Gaining International Attention

    G. Yin,1 D. Li,1 M. Li,1 M. Fu.2

    1China Organ Harvest Research Center, Middletown, NY; 2MD Anderson Cancer Center, University of Texas, Houston, TX.

    PurposeThe government of China has responded to allegations that China has been harvesting organs from prisoners of conscience in extrajudicial killings on a large scale…
  • 2018 American Transplant Congress

    Discriminative Accuracy of Physician Assessments of Kidney Transplant Candidate Function by Candidate Age, Sex, and Race

    M. Harhay,1 K. Ranganna,1 L. Levin Mizrahi,1 G. Xiao,1 G. Malat,1 D. Reich,1 S. Guy,1 P. Reese.2

    1Drexel University College of Medicine, Philadelphia, PA; 2Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

    Background: Clinical assessments of patient health status are integral in kidney transplant (KT) waiting list management. Few data exist on the whether the accuracy of…
  • 2018 American Transplant Congress

    Psychosocial Factors Affecting Recipients of Vascular Composite Allotransplantation

    S. Rasmussen, M. Henderson, C. Cooney, J. Shores, W. Lee, D. Segev, G. Brandacher.

    JHU, Baltimore.

    Background: While vascularized composite allotransplantation (VCA) is an increasingly successful therapy, medication non-adherence appears to be an important cause of graft loss. Psychosocial factors predict…
  • 2018 American Transplant Congress

    Parathyroid Cell Xenotransplantation with Ultrapure Alginate Based Microencapsulation Technique

    B. Goncu,1 E. Yucesan,2 H. Basoglu,3 M. Celikten,1 O. Huseyinbas,1 B. Ozdemir,1 N. Ozten Kandas,4 F. Akbas,5 Y. Ersoy,6 E. Aysan.6

    1Bezmialem Vakif University, Experimental Research Center, Istanbul, Turkey; 2Bezmialem Vakif University, Institute of Life Sciences and Biotechnology, Istanbul, Turkey; 3Bezmialem Vakif University, Faculty of Medicine, Department of Biophysics, Istanbul, Turkey; 4Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey; 5Bezmialem Vakif University, Faculty of Medicine, Department of Medical Biology, Istanbul, Turkey; 6Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey.

    Permanent hypoparathyroidism (PH) is a serious clinical condition and unique treatment option is parathyroid allotransplantation (PA). The most important obstacle for PA is an immune…
  • 2018 American Transplant Congress

    NKG2C+CD57+ NK (G2C+57+) Cells Expanded by CMV Infection Are Highly Responsive to Allo-Antibody (Ab)-Mediated NK Cell Stimulation

    B. Shin,1 D. Puliyanda,2 H. Pizzo,2 S. Jordan,2 M. Toyoda.1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; 2Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: Active CMV infection is known to be associated with risk for ABMR in allograft recipients. Ab-dependent cellular cytotoxicity (ADCC) primarily mediated by NK cells…
  • 2018 American Transplant Congress

    Genetic Risk Factors of Post-Transplant Thrombocytopenia in Kidney Allograft Recipients

    D. Min,1 Y. Chang,2 T. Shah.3

    1College of Pharmacy, Western University of Health Sciences, Pomoma, CA; 2National Institute of Transplantation Foundation, Los Angeles, CA; 3Multiorgan Transplantation Center, St. Vincent Medical Center, Los Angeles, CA.

    Background: Posttransplant thrombocytopenia is prevalent after renal transplantation, which is associated with increased risk of bleeding and other complications. The CXC motif chemokine 12 (CXCL12)…
  • 2018 American Transplant Congress

    Kidney Transplantation (KTx) Using Kidneys from Deceased Donors (DD) with Severe AKI Does Not Negatively Impact 1 Year Biopsy Chronic Changes

    A. Kumar, A. Srinivasan, A. Mathur, J. Huskey, H. Khamash, M. Smith, A. Moss, K. Reddy, R. Heilman.

    Mayo Clinic, Phoenix.

    BackgroundDespite the persistent donor shortage, donor kidneys with an acute kidney injury are declined. The aim of this study to determine the difference in biopsy…
  • 2018 American Transplant Congress

    Late Conversion from Calcineurin Inhibitors to Belatacept is Associated with a Sustained Improvement in Kidney Allograft Function

    S. Sethi, J. Choi, A. Vo, R. Najjar, A. Peng, S. Jordan, E. Huang.

    Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.

    Introduction: Belatacept was shown to have longer kidney graft survival and higher eGFR at 7 years than a calcineurin inhibitor (CNI)-based regimen in the BENEFIT…
  • 2018 American Transplant Congress

    Long-Term Effects of Ketoconazole in Rapid Tacrolimus Metabolizers Post-Renal Transplantation

    J. Ching,1 S. Anders,1 M. Janusek,1 L. Hutchinson,1 A. Freeman,1 U. Patel,1 A. Mohammed,4 H. Bohorquez.2,3

    1Department of Pharmacy, Ochsner Clinical Foundation, New Orleans, LA; 2Multi-Organ Transplant Institute, Ochsner Clinical Foundation, New Orleans, LA; 3The University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, LA; 4Academic Center, Ochsner Clinical Foundation, New Orleans, LA.

    Introduction: Genetic polymorphisms in cytochrome P-450 enzymes can cause variations in tacrolimus (tac) metabolism. Ketoconazole (keto), a potent CYP450 and P-glycoprotein inhibitor, can be used…
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