Am J Transplant, Volume 18, Suppl 3 Archives - Page 173 of 211 - ATC Abstracts

2018 American Transplant Congress
Lymph Node Stromal Laminins Modulate the Dynamic Balance of the Treg/Th17 Axis
L. Li, T. Simon, W. Piao, Y. Xiong, V. Saxena, T. Zhang, C. Wagner, J. Bromberg.
University of Maryland, Baltimore, MD.
Background: Tolerance and immunity are associated with differential expression of lymph node (LN) stromal laminins α4β1γ1 (411) and α5β1γ1 (511), respectively, which determine how alloreactive…
2018 American Transplant Congress
Clinical Trials and Electronic Health Records
J. Chen, S. Bhattachrya, M. Sirota, M. Sarwal, A. Butte.
Institute for Computational Health Sciences, University of California San Francisco, San Francisco; Deaprtment of Surgery, University of California San Francisco, San Francisco.
Background. Ethnic and gender disparities in solid organ transplantation (tx) have social and clinical implications.General disparities for donor access and complications within clinical-trial, national and…
2018 American Transplant Congress
CMV-Specific CD8+ T-Cell Immune Competence Score as Predictor of Outcome for CMV Infection after Transplantation
A. Meesing,¹ R. Abraham,² R. Razonable.¹
¹Division of Infectious Diseases, Mayo Clinic, Rochester, MN; ²Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Introduction: Control of cytomegalovirus (CMV) infection after solid organ transplantation (SOT) requires a functional immune system. We assessed the utility of a flow cytometric assay…
2018 American Transplant Congress
Daptomycin Minimum Inhibitory Concentration (MIC) of Vancomycin Resistant Enterococcal (VRE) Blood Isolates Correlates with Allograft Failure in Orthotopic Liver Transplant (OLT) Recipients
R. Lee,¹ G. Haidar,² J. Lewis,³ S. Arif,⁴ J. Hand,⁵ E. Holaday,⁶ H. Clauss,⁶ J. Goldman,⁷ A. Nellore.¹
¹University of Alabama at Birmingham, Birmingham, AL; ²University of Pittsburgh Medical Center, Birmingham, AL; ³University of Virginia, Charlottesville, VA; ⁴Duke University, Durham, NC; ⁵Oschner Medical Center, New Orleans, LA; ⁶Department of Internal Medicine, Temple University, Philadelphia, PA; ⁷Temple University, Philadelphia, PA; ⁸Swedish Medical Center, Seattle, WA.
Background: Enterococci are one of the leading causes of nosocomial infection in after OLT. Unfortunately, treatment options for enterococci that are resistant to first-line agents…
2018 American Transplant Congress
Isavuconazole – The Real-World Use Experience
H. Hassouna, V. Athans, K. Brizendine.
Cleveland Clinic Foundation, Cleveland, OH.
Isavuconazole (ISV) is a new triazole approved for treatment of mucormycosis and aspergillosis. Data on its effectiveness outside clinical trials and in patients receiving prior…
2018 American Transplant Congress
BLyS^-/- Rats to Prevent Alloantibody Production
N. Bath,¹ B. Verhoven,¹ N. Wilson,¹ S. Reese,² L. Coons,¹ S. Panzer,² A. Djamali,² R. Redfield.¹
¹Surgery, University of Wisconsin, Madison, WI; ²Medicine, University of Wisconsin, Madison, WI.
Introduction: Antibody mediated rejection (AMR) is a major cause of kidney allograft failure. APRIL (A Proliferation Inducing Ligand) and BLyS (B Lymphocyte Stimulator) are two…
2018 American Transplant Congress
Rhesus-Specific Anti-Thymocyte Globulin as an Adjuvant to Costimulatory-Blockade-Based Immunotherapy
M. Mulvihill,¹ B. Ezekian,¹ Q. Gao,¹ K. Samy,¹ R. Davis,¹ F. Leopardi,¹ A. Belli,² W. Flores,² A. Buzby,² K. Reimann,² B. Collins,¹ A. Kirk.¹
¹Department of Surgery, Duke University, Durham, NC; ²MassBiologics, University of Massachusetts Medical School, Boston, MA.
Background Belatacept targets de novo alloimmune responses with minimal off target effects in renal transplantation, though adjuvant therapy is required to control costimulation-blockade resistant rejection…
2018 American Transplant Congress
The Role of Ex Vivo Normothermic Preservation in Minimizing Postreperfusion Syndrome in Liver Transplantation
A. Hassan, J. Cywinski, Q. Liu, D. Pezzati, D. Yang, L. Liu, G. Iuppa, K. Hashimoto, F. Aucejo, M. Fujiki, B. Eghtesad, S. Irefin, J. Fung, K. Abu-Elmagd, C. Miller, C. Quintini.
Transplant Surgery, Cleveland Clinic, Cleveland.
Background:Graft reperfusion holds a major challenge during liver transplantation. NMP may improve post-reperfusion hemodynamics, reduce vasopressor and blood product transfusion.Methods:15 patients with liver transplantation after…
2018 American Transplant Congress
The Prognostic Implications of Renal Function Recovery and Delayed Graft Function in Kidney Transplantation
S. Sandal, M. Cantarovich, A. Ramankumar, N. Saberi, C. Saw, D. Baran, P. Chaudhury, S. Paraskevas, J. Tchervenkov.
MUHC, Montreal, Canada.
Introduction: Lack of renal function recovery (RFR), 90 days after acute kidney injury (AKI) is a contributor to inferior renal outcomes and mortality. Ischemia and…
2018 American Transplant Congress
Timeline and Histopathological Characteristics of Graft Failure after Kidney Transplantation: What is Preventable and What is Not?
S. Parajuli, F. Aziz, N. Garg, B. Muth, M. Mohamed, W. Zhong, B. Astor, D. Mandelbrot, A. Djamali.
University of Wisconsin, Madison.
Background: There is limited information on the histopathological characteristics of kidney transplant recipients (KTRs) with graft failure at different post-transplant time intervals. Methods:We addressed this…