Am J Transplant, Volume 18, Suppl 3 Archives - Page 173 of 211 - ATC Abstracts

2018 American Transplant Congress
SIRT1-Ikaros Axis Promotes Macrophage M2 Polarization and Protects Liver Graft from Ischemia-Reperfusion Injury
K. Nakamura,¹ S. Kageyama,¹ X. Li,² A. Aziz,¹ R. Sosa,³ E. Reed,³ F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, UCLA, Los Angeles, CA; ²NIEHS, Durham, NC; ³Pathology, UCLA, Los Angeles, CA.
Although pre-clinical studies have reported the efficacy of Sirtuin 1 (SIRT1) to protect livers from ischemia-reperfusion injury, its clinical relevance in liver transplantation (LT) has…
2018 American Transplant Congress
Inflammation in Scarred Areas (I-IFTA) is a Reflection of Parenchymal Injury (Response to Wounding) Not T Cell-Mediated Rejection
P. Halloran, J. Chang, K. Famulski.
Medicine, University of Alberta, Edmonton, AB, Canada.
Inflammation in fibrotic renal parenchyma (i-IFTA) is associated with decreased graft survival but by Banff rules is not diagnostic for rejection. Some researchers believe that…
2018 American Transplant Congress
Validation of a Transplant Knowledge Quiz and Its Impact on Outcomes in Kidney Transplant Recipients
H. Corbo, N. Patel, N. Pilch, V. Rohan, J. Fleming, T. Harrison, J. Hardcopf, B. O'Brien, C. Perez, P. Baliga, H. Meadows, D. Taber.
Medical University of South Carolina, Charleston.
The aim of this study is to determine if transplant quiz scores given prior to discharge were predictive of known patient risk factors and if…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
2018 American Transplant Congress
Do Recent Heart Transplant Patients Need to Reside Close to the Transplanting Center? A Look at the Impact of Commuting Times on Clinical Outcomes
A. Velleca, E. Kransdorf, J. Patel, M. Kittleson, S. Dimbil, R. Levine, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Compliance after heart transplantation (HTx) is crucial to ensure adequate drug dosing and avoidance of complications especially within the first six months. To ensure…
2018 American Transplant Congress
A Population Based Study of Incidence of Post Kidney Transplant Malignancies
D. Sexton,¹ J. O'Neill,² P. O'Kelly,¹ S. Murray,¹ S. Deady,³ E. O'Leary,³ P. Morris,⁴ P. Conlon.¹
¹Department of Nephrology & Transplantation, Beaumont Hospital Dublin, Royal College of Surgeons Ireland, Dublin, Ireland; ²Department of Otolaryngology, Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland; ³National Cancer Registry Ireland, Cork, Ireland; ⁴Department of Oncology, Beaumont Hospital, Dublin, Ireland.
IntroductionWe aimed to report national standardised incidence for malignancy post transplant compared to the general population stratified by solid organ categories. In this study we…
2018 American Transplant Congress
Molecular Assessment of Post-Transplant Glomerular Disease Comparing to Transplant Glomerulopathy
E. Akalin,¹ M. e Silva,² Y. Bao,¹ V. Bontha,³ M. Ajaimy,¹ V. Mas,³ P. [Oacute] Broin.²
¹Montefiore Medical Center, Bronx, NY; ²National University of Ireland Galway, Galway, Ireland; ³University of Virginia, Charlottesville.
Background: Intragraft gene expression profiles of glomerular disease after kidney transplantation has not been well described other than transplant glomerulopathy (TGP) which develops due to…
2018 American Transplant Congress
Differential Effects of Inhibiting Glycolysis on Human Treg Subsets
N. Tanimine, B. Priyadharshini, S. Germana, L. Turka.
Department of Surgery, Massachusetts General Hospital, Boston, MA.
Regulatory T cells (Tregs) are a promising therapeutic tool for inducing transplantation tolerance. Tregs can be divided into those of thymic origin (tTreg) and those…
2018 American Transplant Congress
Variation in Post-Transplant Opiate Prescribing Patterns across Transplant Centers
A. Mathur, D. Ubl, J. Harbell, K. Croome, C. Taner, J. Heimbach, A. Moss, E. Habermann.
Mayo Clinic, Rochester, Phoenix, Jacksonville.
Background: Excess opiate prescribing has led to an epidemic, and evidence to guide abdominal transplant practice is lacking. We aimed to identify variation in opiate…
2018 American Transplant Congress
Humoral Immune Response to Seasonal Influenza Infection in Transplant Recipients
C. Hirzel,¹ V. Ferreira,¹ A. L'Huillier,¹ K. Hoschler,² E. Cordero,³ G. Reid,⁴ J. Englund,⁵ A. Limaye,⁶ A. Humar,¹ D. Kumar.¹
¹UHN, Toronto, Canada; ²Public Health England, London, United Kingdom; ³REIPI, Sevilla, Spain; ⁴LUMC, Chicago; ⁵SCH, Seattle; ⁶UOWMC, Seattle.
Background: Little is known about the serologic response to natural influenza infection in transplant recipients. We describe the hemagglutinin antibody response to influenza A/H1N1 infection…