Am J Transplant, Volume 18, Suppl 3 Archives - Page 17 of 211 - ATC Abstracts

2018 American Transplant Congress
Presentation and Outcomes of Post-Transplant Proliferative Disorder at a Single Institution Pediatric Transplant Center
G. Ramos-Gonzalez,¹ A. Allain,¹ T. Agur,¹ L. O'Melia,¹ S. Staffa,² S. Burchett,¹ B. Siegele,³ O. Weinberg,³ N. Rodig,¹ R. Fawaz,¹ T. Singh,¹ D. Freiberger,¹ K. Heung Bae.¹
¹Pediatric Transplant Center, Boston Children's Hospital, Boston, MA; ²Department of Surgery, Boston Children's Hospital, Boston, MA; ³Department of Pathology, Boston Children's Hospital, Boston, MA.
Purpose: The aim of this study was to characterize features present at the time of post-transplant lymphoproliferative disorder (PTLD) diagnosis, as well as outcomes, following…
2018 American Transplant Congress
Ex-Vivo Subnormothermic Oxygenated Machine Perfusion of Rodent Hindlimb: Feasibility Study to Elongate Preservation Time of Vascularized Composite Allograft
L. Burlage,^1,2 A. Lellouch,^3,4 S. Tessier,¹ C. Pendexter,¹ S. Cronin,¹ M. Schol,³ M. Randolph,³ R. Porte,² L. Lantieri,⁴ C. Cetrulo,³ K. Uygun.¹
¹Surgery, Massachusetts General Hospital/Harvard Medical School, Boston; ²Surgery, University Medical Center Groningen, Groningen, Netherlands; ³Plastic Surgery, Massachusetts General Hospital/Harvard Medical School, Boston; ⁴Plastic Surgery, European George Pompidou Hospital, Paris, France.
PURPOSE: A pressing challenge in the field of VCA is adequate tissue preservation. Static cold preservation, successfully used in field of solid organ transplantation, greatly…
2018 American Transplant Congress
Correlation of Kidney Transplant Human Leukocyte Antigen Eplet Mismatching to De Novo Donor Specific Antibody Production and Post-Transplant Outcomes
R. Samudralwar,¹ K. Szempruch,¹ C. Reuter,³ B. Franz,⁴ R. Lee,¹ E. Weimer,⁴ R. Detwiler,² T. Kozlowski,² J. Schmitz.⁴
¹Department of Pharmacy, Universitty of North Carolina Medical Center, Chapel Hill, NC; ²Department of Surgery, Universitty of North Carolina Medical Center, Chapel Hill, NC; ³Department of Pharmacy, Ochsner Health System, New Orleans, LA; ⁴Department of Pathology, University of North Carolina Medical Center, Chapel Hill, NC.
Human Leukocyte Antigen (HLA) eplet mismatches (EMM) are associated with the development of de novo donor specific antibody (dnDSA) in kidney transplant recipients (KTRs). There…
2018 American Transplant Congress
FSGS Pattern with Podocyte Proliferation and Heavy Proteinuria Combined Late Antibody Mediated Rejection of Renal Allograft: Collapsing Glomerulopathy or Transplant Podocytopathy?
J. Wen, M. Zhang, F. Xu, J. Chen, D. Cheng, X. Ni, X. Li.
National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China.
Background: Collapsing Glomerulopathy is a pathologically and clinically distinct variant of FSGS with poor prognosis.Hemodynamic disturbances may play a role in the development of the…
2018 American Transplant Congress
Machine Learning to Assess Kidney Donor Risk
A. Shah, M. Li, Z. Chen.
Thomas Jefferson University, Philadelphia, PA.
Organ quality estimation is critical in allocation and organ acceptance in renal transplantation. Standard methods determine the likelihood of an outcome of interest utilizing Cox…
2018 American Transplant Congress
High GFR in Kidney Donors is Associated with Increased Risk of Proteinuria and Diabetes
D. Keys, S. Riad, V. Vakil, S. Jackson, D. Berglund, A. Matas.
University of Minnesota, Minneapolis, MN.
Background: Measured glomerular filtration rate (GFR) has been part of the donor evaluation to rule out low GFR donors from taking undue risk for ESRD.…
2018 American Transplant Congress
Steroid Avoidance in Renal Transplant Patients Treated with Everolimus and Low-Exposure Tacrolimus
T. Sandes-Freitas,^1,2 M. Sales,¹ J. Oliveira,¹ M. Oliveira,¹ G. Dantas,² C. Girão,¹ R. Esmeraldo.¹
¹Hospital Geral de Fortaleza, Fortaleza, Ceara, Brazil; ²Universidade Federal do Ceara, Fortaleza, Ceara, Brazil.
Background: Previous studies reported efficacy and safety of steroid-free regimens after kidney transplant (KT). However, there is no robust evidence on this strategy in patients…
2018 American Transplant Congress
Presence of Chronic Vascular Lesions on Allograft Biopsy is Associated with Greater Improvement in Renal Function after Conversion from Tacrolimus to Belatacept
M. Perez-Saez,^1,2 B. Yu,¹ A. Uffing,¹ N. Murakami,¹ J. Azzi,¹ S. El Haji,³ S. Gabardi,³ L. Riella.¹
¹Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; ²Servicio de Nefrologia, Hospital del Mar, Barcelona, Spain; ³Pharmacy Services, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Background: Conversion from tacrolimus to belatacept has been shown to be beneficial for an increasing number of kidney transplant (KT) patients. However, predicting factors for…
2018 American Transplant Congress
Long-Term Outcomes of a Steroid-Free, Belatacept-Based Immunosuppressive Regimen Plus Sirolimus Using Alentuzumab Induction in Renal Transplantation
A. Guasch,¹ A. Ghali,¹ S. Mead,¹ A. Mehta,¹ H. Xu,² A. Kirk.²
¹Emory Transplant Center, Emory University, Atlanta, GA; ²Dept of Surgery, Duke University, Durham, NC.
The toxicities of CNIs and steroids have a negative impact on kidney transplantation. Belatacept is a safe, non-nephrotoxic alternative to CNIs, that may lead to…
2018 American Transplant Congress
Taking Specific Steps to Pursue Living Donor Kidney Transplant is Associated with Greater Odds of Having a Potential Living Donor Identified
A. Ali,¹ D. Toews,¹ N. Singh,¹ A. Ayub,¹ C. Richardson,¹ S. Dano,¹ D. Wong,¹ J. Peipert,² A. Waterman,² M. Novak,¹ I. Mucsi.¹
¹University Health Network, Toronto, ON, Canada; ²David Geffen School of Medicine, UCLA, Los Angeles, CA.
Background:When planning interventions to increase living donor kidney transplant (LDKT), it is important to understand what actions can patients take that are associated with an…