Am J Transplant, Volume 18, Suppl 3 Archives - Page 167 of 211 - ATC Abstracts

2018 American Transplant Congress
Phosphoproteomic Analysis of Mouse Hepatic Ischemia/Reperfusion Injury
A. Zarrinpar,² S. Duarte,¹ Y. Lai.²
¹Surgery, University of California, Los Angeles, CA; ²Surgery, University of Florida, Gainesville, FL.
Introduction: Hepatic ischemia/reperfusion injury (IRI) is a major risk factor for acute rejection and early graft dysfunction in liver transplantation. The large and complex landscape…
2018 American Transplant Congress
Early versus Late Cytomegalovirus Prophylaxis after Kidney Transplant
M. Harris, J. Byrns, J. Gommer, M. Laub, M. Ellis.
Duke University Hospital, Durham, NC.
Background: Prophylaxis against cytomegalovirus (CMV) is recommended in high-risk patients (CMV D+/R-) and those who are CMVR+ and getting T-cell depletional therapy. It is unclear…
2018 American Transplant Congress
Early Blockade of Toll-Like Receptor 4 Reduces Ischemia-Reperfusion Injury and Improves Islet Transplantation Outcomes
C. Chang,¹ M. Lawrence,² R. Kane,¹ B. Naziruddin.³
¹Institute of Biomedical Studies, Baylor University, Waco; ²Baylor Scott & White Research Institute, Dallas; ³Baylor Simmons Transplant Institute, Dallas.
Purpose: Inflammatory damage to islets during isolation is a major hurdle for success in transplantation. We investigated the safety and therapeutic potential of pharmacological blockade…
2018 American Transplant Congress
Is KDPI Valid for Hepatitis C Aviremic Kidneys?
L. Sibulesky,¹ C. Kling,¹ C. Blosser,² C. Johnson,² A. Limaye,² R. Bakthavatsalam,¹ N. Leca,² J. Perkins.¹
¹Surgery, University of Washington Medical Center, Seattle, WA; ²Medicine, University of Washington Medical Center, Seattle, WA.
KDRI is an estimate of post-transplant kidney graft failure. It is based on ten donor factors that independently affect transplant outcomes, including HCV status from…
2018 American Transplant Congress
The Impact of Rituximab Dose on Hepatitis B Virus Reactivation in HBsAg-Negative/anti-HBc-Positive Kidney Transplant Recipients
J. Lee,¹ J. Park,² Y. Jung,¹ D. Kim,¹ J. Lee,¹ S. Song,³ J. Lee,⁴ J. Lee,¹ B. Kim,⁵ M. Kim,¹ S. Kim,¹ Y. Kim,¹ K. Huh.¹
¹Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Internal Medicine (Gastroenterology), Yonsei University College of Medicine, Seoul, Korea; ³Surgery, Ewha Womans University, School of Medicine, Seoul, Korea; ⁴Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Korea; ⁵Internal Medicine (Nephrology), Yonsei University College of Medicine, Seoul, Korea.
Background: Hepatitis B virus (HBV) reactivation is well-recognized complication of rituximab. Although use of rituximab for sensitized patients continues to increase in kidney transplantation, the…
2018 American Transplant Congress
mTOR Inhibition with Everolimus in De Novo Living Donor Liver Transplantation – 24-Months Results from the H2307 Pivotal Trial
L. Jeng,¹ S. Lee,¹ A. Soin,¹ S. Uemoto,¹ D. Maluf,¹ J. Emond,¹ M. Meier,² J. Kochuparampil,² C. Sips,² S. Kaneko,³ G. Levy.¹
¹H2307 Study Group, Taichung, Taiwan; ²Novartis Pharma AG, Basel, Switzerland; ³Novartis Pharma KK, Tokyo, Japan.
Purpose: Everolimus (EVR) with reduced-dose tacrolimus (rTAC) has been shown to be efficacious in preventing graft rejection and improving renal function in deceased-donor liver transplant…
2018 American Transplant Congress
EVLP on Donor Lungs: National Trends and Outcomes
R. Lehman,¹ R. Carrico,¹ K. Uccellini,¹ K. Chan,² T. Whelan.³
¹United Network for Organ Sharing, Richmond, VA; ²Univ of Michigan, Ann Arbor, MI; ³Medical Univ of South Carolina, Charleston, SC.
Purpose: The OPTN/UNOS added fields to the deceased donor registration form on 3/31/2015 to capture the intent to utilize ex vivo lung perfusion (EVLP) on…
2018 American Transplant Congress
Islet Xenotransplantation: A Quest for Clinically Available Immunosuppression Regimens
Q. Gao, R. Davis, M. Mulvihill, M. Song, F. Leopardi, M. Ribeiro, T. How, G. Devi, B. Collins, A. Kirk.
Department of Surgery, Duke University Medical Center, Durham, NC.
IntroductionThe field of porcine islet xenotransplantation has made significant progress in non-human primate studies in recent years. However, one major barrier preventing clinical translation of…
2018 American Transplant Congress
Thirty-Six Consecutive Kidney Transplants in Recipients with Atypical Hemolytic Uremic Syndrome: A Single-Centre Experience
E. Favi,¹ G. Ardissino,² D. Cresseri,³ J. Brocca,¹ S. Testa,⁴ F. Tel,⁴ A. Giussani,¹ C. Colico,¹ C. Beretta,¹ M. Ferraresso.¹
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; ²Centre for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Milan, Italy; ³Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy; ⁴Pediatric Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.
Background. Due to high recurrence rate, poor kidney transplant (KTx) survival has been reported for recipients with atypical hemolytic uremic syndrome (aHUS). More recently, prophylaxis…
2018 American Transplant Congress
Marijuana Use Should Not Preclude Consideration for Kidney Transplantation
K. Fabbri, T. Anderson-Haag, A. Spenningsby, A. Israni, R. Nygaard, P. Stahler.
Hennepin County Medical Center, Minneapolis, MN.
Purpose: Policies for transplant eligibility for tobacco and marijuana (MJ) users vary among transplant centers. The aim of this study was to compare the impact…