2018 American Transplant Congress
Weight Changes before and after Kidney Donation
IntroductionLiving kidney donors remain at low risk of end stage kidney disease but obese and overweight donors' risk is increased. We aimed to describe the…2018 American Transplant Congress
Donor Deficiency of RIP3 Phosphokinase Activity Shortens Cardiac Allograft Survival in the Setting of Costimulation Blockade
Surgery, Duke University, Durham, NC.
Receptor-interacting protein kinase 3 (RIP3) is critical for necroptosis in the setting of inflammation. It has been shown that kidney and heart allografts deficient in…2018 American Transplant Congress
Pre-Transplant Assessment of AMR Risk by Novel Donor/recipient Non-HLA Variants
1UCSF, San Francisco; 2Johns Hopkins University, Baltimore.
Transplant (tx) injury from antibody mediated (AMR) and T cell mediated (CMR) rejection, limits indefinite survival after HLA mismatched organ tx. AMR is incompletely diagnosed…2018 American Transplant Congress
Mortality and Kidney Transplantation Outcomes among Chronic Dialysis Patients Who Are Seropositive for Hepatitis C Virus
1Univ of Pennsylvania, Philadelphia, PA; 2Univ of Alabama, Birmingham, AL; 3DaVita, Minneapolis, MN.
Hepatitis C virus (HCV) infection is common among patients receiving chronic dialysis. However, few studies have examined both survival on dialysis as well as transplantation…2018 American Transplant Congress
Safety and Efficacy of Tocilizumab (anti-IL6R, TCZ) Therapy in the Treatment of Chronic Antibody Mediated Rejection (cABMR) in Pediatric Renal Transplant Recipients
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA.
Background: Development of de novo Donor specific antibodies (DSA) post renal transplantation puts pediatric patients(pts) at risk for ABMR and allograft failure (Kim JJ AJT…2018 American Transplant Congress
Complex Combined Thoracic/liver Transplant: A Seven Year Experience
Liver and Pancreas Transplant, UCLA, Los Angeles, CA.
Background: While rare, combined Thoracic/Liver transplants are employed with increasing frequency. Consistent data regarding the technical conduct, patient selection and outcomes in this highly complex…2018 American Transplant Congress
The Role of CD46 in Early Islet Engraftment in a Dual Transplant Model
Department of Surgery, Duke University School of Medicine, Durham, NC.
IntroductionMembrane cofactor protein (CD46) is known to attenuate the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46…2018 American Transplant Congress
Recurrence of Immunoglobulin A Nephropathy in Related Donor Kidney Transplant Recipients
BackgroundSecondary to an increase in the graft survival rates in patients undergoing successful kidney transplantation, an increase in the occurrence of recurrent glomerulonephritis has been…2018 American Transplant Congress
Belatacept in Kidney Transplant Recipients with Preformed Donor Specific Anti-HLA Antibodies: Results of the BELACOR Trial
IntroductionAntibody-mediated rejection (ABMR) is currently a critical question in kidney transplant recipient with immunological risk factors such as pre transplant donor-specific anti HLA antibodies (DSA).…2018 American Transplant Congress
Longitudinal Analysis of Community Respiratory Virus Infection in Kidney Transplant Recipients
David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Purpose: Community respiratory viruses (CRVs) cause significant morbidity and mortality in solid organ transplant recipients, but little is known about the epidemiology of CRV infections…
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