Am J Transplant, Volume 18, Suppl 3 Archives - Page 161 of 211 - ATC Abstracts

2018 American Transplant Congress
Engineering Regulatory T Cells with Interleukin (IL-)2 Nanogel for Improved Alloimmune Suppression
S. Eskandari,¹ M. Bandeira Melo,² J. Assaker,¹ A. Mansouri,¹ S. Cai,¹ B. Al Dulaijan,¹ M. Mohamed,¹ D. Irvine,² J. Azzi.¹
¹Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; ²Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA.
Clinical trials of adoptively transferred regulatory T cells (TRegs) have been hindered by the short lifespan of these transferred TRegs. Systemic injection of low-dose interleukin…
2018 American Transplant Congress
Waitlist Survival is Approaching Survival after Kidney Transplantation
A. Rana, B. Murthy, C. O'Mahony, J. Goss.
Abdominal Tranplantation, Baylor College of Medicine, Houston, TX.
Backround: Kidney transplantation confers a significant survival benefit to its recipients. Our objective was to reassess this survival benefit in light of improving outcomes on…
2018 American Transplant Congress
Few Gender Differences in Attitudes and Experiences after Live Kidney Donation, with Minor Changes over Time
J. Wadström,^1,2 B. von Zur-Mühlen,³ S. Yamamoto.³
¹Department of Transplantation Surgery, Karolinska University Hospital, Huddinge, Sweden; ²Department of Surgery/Transplantation, Hamad Medical Corporation, Doha, Qatar; ³Department of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.
Background: We sought to study gender differences and differences over time with respect to demographics, relation to recipient, donor motives, and experiences of live kidney…
2018 American Transplant Congress
Split/Reduced Liver Grafts in Adult Liver Transplantation, No Longer a Risk for Graft Loss
K. Sasaki, D. Firl, J. McVey, G. Iuppa, M. Fujiki, T. Diago Uso, F. Aucejo, B. Eghtesad, C. Quintini, C. Miller, K. Hashimoto.
General Surgery, Cleveland Clinic, Cleveland, OH.
Objective:Split/reduced graft liver transplantation(SRLT), while widely accepted in pediatrics, remains underutilized in adults. SRLT is considered a negative factor for graft quality(HR;1.52) in liver donor…
2018 American Transplant Congress
Waitlist Outcomes and Access to Liver Transplantation for HIV+ Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,^1,2 C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
Liver disease is a leading cause of death for HIV+ individuals, and the number of HIV+ liver transplant recipients is increasing. However, since UNOS does…
2018 American Transplant Congress
Racing to Activation: Using LEAN Principles to Effectively Manage Your Waitlist with Predicted Improved Outcomes
L. Curry, V. Rao, D. Cassidy, V. Rohan, D. Dubay, N. Pilch, S. Gray.
MUSC, Charleston.
Introduction: In July 2017, our waitlist was approximately 950 pts, 36% which were inactive. One coordinator & one program assistant managed the kidney waitlist. Review…
2018 American Transplant Congress
The Results of the PRISM (Prediction of Rejection In Sensitized Patient Blood SaMples) Trial with a Novel Bioassay
F. Vincenti, A. Schroeder, S.-C. Hseish, J. Liberto, P. Towfighi, C. Koh, T. Sigdel, M. Sarwal.
Surgery and Medicine, University of California San Francisco, San Francisco.
Background. kSORT, a 17 gene blood biomarker, has been retrospectively validated for detection of BPAR and immune quiescence in kidney tx. This is the first…
2018 American Transplant Congress
The Likelihood of Re-Transplantation in Patients Undergoing Allograft Nephrectomy
G. Lucisano,¹ P. Brookes,² E. Santos-Nunez,² N. Firmin,² N. Gunby,² S. Hassan,¹ A. Gueret-Wardle,¹ M. Willicombe,¹ D. Taube.¹
¹Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom.
Introduction: transplant nephrectomy (NX) is a known cause of allosensitisation after graft failure. As yet, there is no consensus for the management of the patient…
2018 American Transplant Congress
Global Expression Profiles of miRNA and Expression Patterns and Localization of the miR-21 in One-Hour Biopsy Specimens of Human Kidney Tansplantation from Donors after Cardiac Death
M. Kusaka,¹ N. Fukami,¹ H. Sasaki,¹ A. Kawai,¹ T. Kenmochi,² T. Ito,² R. Shiroki,¹ K. Hoshinaga.¹
¹Urology, Fujita-Health University, Toyoake/Aichi, Japan; ²Transplant Surgery, Fujita-Health University, Toyoake/Aichi, Japan.
Because of the global shortage of renal grafts, kidney transplantation (KTx) from donors after cardiac death (DCDs) is an alternative way of obtaining KTx from…
2018 American Transplant Congress
Non-Invasive Imaging Modalities for Immune Monitoring of Vascularized Composite Allografts Using a Translational Large Animal Model
J. Etra,¹ K. Cilwa,² G. Furtmueller,¹ A. Leto Barone,¹ K. Kolegraff,¹ E. Elster,¹ W. Lee,¹ G. Brandacher.¹
¹Department of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ²Naval Medical Research Center, Silver Springs, MD; ³Department of Surgery, Uniformed Services, University of Health Sciences and Walter Reed National Military Medical Center, Bethesda, MD.
PurposeImmunological complications and skin rejection remains an obstacle in broadening the applicability of vascularized composite allotransplantation (VCA). Currently, diagnosis of rejection relies on skin biopsies…