2018 American Transplant Congress
Validation of an Integrative and Dynamic Prognostic Score for Response to Therapy in Solid Organ Transplants
Paris Translational Center for Organ Transplantation, Paris, France.
Drug development in transplantation has diminished due to the lack of suitable endpoints for predicting graft failure. We sought to validate the performance of an…2018 American Transplant Congress
Pre-Donation Body Mass Index Associations with Outcomes in Living Kidney Donors: A Single Centre Experience
West London Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
Background. Living kidney donor (LD) eligibility criteria have expanded as a result of excellent donor outcomes and increasing organ demand. However, considerable variability exists between…2018 American Transplant Congress
Do Reconstruction Techniques for Two Renal Arteries Affect Long-Term Graft Survival after Living Donor Renal Transplantation?
Transplant Surgery, UCSF, San Francisco, CA.
Background: Living donor kidneys with two arteries can be revascularized using various techniques depending on anatomy. We hypothesized that the revascularization technique could impact long-term…2018 American Transplant Congress
The Financial Impact of the Opioid Epidemic on Kidney Transplantation Readmissions
Research has demonstrated increased annual medical costs in patients who abuse opioids, estimated at up to $18,000 per patient and $29 billion overall in the…2018 American Transplant Congress
Development of an Individualized Online Shared Decision Making Tool for Kidney Transplant Candidates
Background: Inadequate knowledge hinders informed decision making in kidney transplant candidates. We conducted qualitative interviews and focus groups with patients and providers to inform development…2018 American Transplant Congress
Robust Hematopoietic Mixed Chimerism and Donor-Specific Skin Allograft Tolerance after Non-Genotoxic Anti-CD117 Immunotoxin Conditioning and Donor Bone Marrow Allotransplantation
Establishing hematopoietic chimerism enables donor-specific allograft tolerance; however, chimerism protocols typically require either genotoxic conditioning or mega-doses of donor bone marrow cells (BMC), impeding clinical…2018 American Transplant Congress
Macrophage Depletion of RCMV-Latently Infected Allografts Ameliorates Accelerated Chronic Cardiac Rejection
1Abdominal Organ Transplantation, OHSU, Portland, OR; 2VGTI, OHSU, Portland, OR.
PurposeLatent donor rat cytomegalovirus (RCMV) infection accelerates chronic rejection (CR) in a heterotopic rat heart transplant model. RCMV latency is associated with an influx of…2018 American Transplant Congress
No Kidney Left Behind: Are We Maximizing Utilization of Deceased Donors with AKI?
Renal Transplantation, Columbia University, New York City, NY.
Introduction: Kidneys from donors with elevated terminal creatinine (Cr) and acute kidney injury (AKI) can be transplanted safely, yet many of these organs are not…2018 American Transplant Congress
Temporal Changes in the Characteristics and Sensitization of Kidney Paired Donation Registrants
In order to utilize a willing but incompatible living donor, candidates must either proceed with incompatible transplantation or find a more compatible match using kidney…2018 American Transplant Congress
Diagnostic Value and Confounding Factors of Urinary Biomarkers in the Non-Invasive Screening of Renal Allograft Inflammation
IntroductionThe value of urinary biomarkers has already been demonstrated in diagnosing acute rejection of the renal allograft, but confounding factors, which may interfere with their…
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