ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Impact of Pre-Transplant Dialysis on ESRD-Free and Patient Survival in Heart Transplant Alone and in Simultaneous Heart/Kidney Transplant Recipients: UNOS Data Analysis

    S. Akkina, A. Desai, J. Yoo, S. Hou, R. Parasuraman.

    Medicine, Loyola University, Maywood, IL.

    It is well known that chronic kidney disease has significant negative impact on post-transplant survival in heart transplant (HTx) recipients. Here we wanted to evaluate…
  • 2018 American Transplant Congress

    A Protocol for the Management of Alemtuzumab Induced Leukopenia in Kidney Transplant Recipients

    S. Hammad, B. Ravichandran, M. Crist, B. Masters.

    University of Maryland Medical Center, Baltimore.

    Purpose: Leukopenia is a common complication following alemtuzumab induction in kidney transplant recipients (KTR), often limiting its use. Our institution developed a protocol to manage…
  • 2018 American Transplant Congress

    Burden of Infectious Complications after Upper Extremity Allotransplantation: A Matched Cohort Study

    A. Conrad,1,2,3 P. Petruzzo,4,5 J. Kanitakis,6 A. Gazarian,7 L. Badet,3,8 P. Vanhems,3,9 O. Thaunat,1,3,10 E. Morelon,1,3,10 A. Sicard.1,3

    1Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon (HCL), Lyon, France; 2Department of Infectious Diseases and Tropical Medicine, HCL, Lyon, France; 3Claude Bernard Lyon 1 University, Lyon, France; 4Department of Transplantation, HCL, Lyon, France; 5Department of Surgery, University of Cagliari, Cagliari, Italy; 6Department of Dermatology, HCL, Lyon, France; 7Clinique du Parc, Lyon, France; 8Department of Urology and Transplantation, HCL, Lyon, France; 9Infection Control and Epidemiology Unit, HCL, Lyon, France; 10INSERM U1111, International Center for Infectiology Research, Lyon, France.

    This study aimed to assess the infectious risk after upper extremity allotransplantation (UEA), a non-vital transplantation procedure requiring lifelong immunosuppression. A matched cohort study was…
  • 2018 American Transplant Congress

    Solid Organ Transplantation and Data Mining: Risk Factors for Invasive Fungal Disease in Heart Transplant Recipients

    N. Barros, D. Xie, C. Yek, T. Liu, X. Li, B. Adams-Huet, J. Martinez, S. Garg, J. Grodin, R. Morelend, A. Amin, F. Aras, J. Thibodeau, P. Mammen, M. Peltz, M. Drazner, W. Ring, R. Haley, R. La Hoz.

    UT Southwestern, Dallas, TX.

    We created a database of solid organ transplant (SOT) recipients using innovative data mining tools. This study describing the epidemiology of invasive fungal disease (IFD)…
  • 2018 American Transplant Congress

    Detection of Different Gene Expression Profiles in CD8+ T Cells from Chronic High EBV Load Carriers after Pediatric Heart and Liver Transplantation

    M. Yamada,1,2 C. Macedo,2 X. Gu,2 M. Michaels,1,2 M. Green,1,2 C. Nguyen,1,2 U. Chandran,3 B. Feingold,1,2 G. Mazariegos,1,2 D. Metes.1,2

    1Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Thomas E. Starzl Transplantation Institute, Pittsburgh, PA; 3Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA.

    Background: EBV infection and post-transplant lymphoproliferative disorders (PTLD) are life-threatening complications of pediatric solid organ transplantation (Tx). The risk for PTLD varies by transplanted organ,…
  • 2018 American Transplant Congress

    Containment of Carbapenem-Resistant Enterobacteriaceae (CRE) Infections at a Solid Organ Transplant Centre

    A. Mularoni,1 G. Martucci,1 S. Gruttadauria,1 M. Campanella,1 F. Tuzzolino,1 G. Arena,1 A. Arcadipane,1 U. Palazzo,1 A. Luca,1 B. Gridelli,1 P. Grossi.2

    1ISMETT-IRCCS, Palermo, Italy; 2University of Insubria, Varese, Italy.

    Objectives The aim is to describe epidemiology and analyze the effectiveness of the intervention in CRE containment in SOT patients (pts).Methods In 2012 a taskforce…
  • 2018 American Transplant Congress

    Linking Donor Ischemia Reperfusion Injury (IRI) to Costimulatory Blockade Resistant Murine Heart Graft Rejection through Complement-Initiated Necroptosis

    R. Ang, N. Chun, A. Ting, P. Heeger.

    Immunology Institute, Translational Transplant Research, Icahn School of Medicine at Mount Sinai, New York, NY.

    We previously showed that prolonged cold ischemic storage (CIS) of donor B6 hearts results in complement dependent, CTLA4Ig-resistant rejection in BALB/c recipients. In this system,…
  • 2018 American Transplant Congress

    How Safe is Crossing the ABO Blood Group Barrier? A Meta-Analysis to Determine the Additive Risk of ABO-Incompatible Kidney Transplantation

    A. de Weerd, M. Betjes.

    Nephrology and Kidney Transplantation, Erasmus Medical Center, Rotterdam, Netherlands.

    Background ABO blood group-incompatible (ABOi) kidney transplantation is considered a safe procedure, with non-inferior outcomes in large cohort studies. Its contribution to living kidney transplantation…
  • 2018 American Transplant Congress

    Frailty Assessment Pilot Study in Older Kidney Transplant Recipients

    B. Abdalla, B. Hale-Durbin, J. Schaenman, C. Lee, G. Danovitch.

    UCLA, Los Angeles, CA.

    Older patients are more often being considered for kidney transplantation, however many candidates are on the waitlist for several years. We sought to evaluate the…
  • 2018 American Transplant Congress

    Anticoagulation in Pediatric Liver Transplantation; the Pros and Cons

    M. Werner,1 R. de Kleine,1 M. de Boer,1 V. de Meijer,1 R. Scheenstra,2 H-.J. Verkade,2 F. Bodewes,2 S. Bontemps,3 T. Lisman,1 R. Porte.1

    1HPB Surgery & Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; 2Pediatric Gastroenterology & Hepatology, University Medical Center Groningen, Groningen, Netherlands; 3Pediatric Intensive Care, University Medical Center Groningen, Groningen, Netherlands.

    Background: Hepatic artery thrombosis (HAT) and portal vein thrombosis (PVT) are serious causes of morbidity and mortality after pediatric orthotopic liver transplantation (OLT). To minimize…
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